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The transcriptional coregulator NAB2 is a target gene for the Wilms' tumor gene 1 protein (WT1) in leukemic cells

The Wilms' tumor gene 1 (WT1) is recurrently mutated in acute myeloid leukemia. Mutations and high expression of WT1 associate with a poor prognosis. In mice, WT1 cooperates with the RUNX1/RUNX1T1 (AML1/ETO) fusion gene in the induction of acute leukemia, further emphasizing a role for WT1 in leukemia development. Molecular mechanisms for WT1 are, however, incompletely understood. Here, we identif

Rules and Tools in the Battle against Superbugs - A call for integrated strategies and enhanced international collaboration to promote antimicrobial drug development

The lack of treatments during the recent Ebola and Zika outbreaks dramatically exposed the vulnerability of the global health system and the dire consequences thereof. But even where therapies against infectious diseases had been available, an additional threat has gained world-wide attention: antimicrobial resistance (AMR). A growing number of microbial organisms are becoming resistant to availab

Coronary Angiography and Intervention in Women Resuscitated From Sudden Cardiac Death

Background Coronary artery disease is the primary etiology for sudden cardiac arrest in adults, but potential differences in the incidence and utility of invasive coronary testing between resuscitated men and women have not been extensively evaluated. Our aim was to characterize angiographic similarities and differences between men and women after cardiac arrest. Methods and Results Data from the

Translanguaging Practices in English Language Teaching in Scandinavian Contexts

With the over-arching aim of contributing to the development of evidence-based teaching practices, this colloquium provides a forum for scholars doing research on language practices in the teaching of English as a foreign/second language (L2) in mainstream schools in Scandinavia. In Sweden, the English teaching profession has long been guided by monolingual, English Only, ideology, particularly at

The illusion of routine as an indicator for job automation with artificial intelligence

The resurgence of artificial intelligence (AI) has empowered organizations to concentrate their research efforts on enhancing decision-making and automation capabilities. This is being pursued with the goal of increasing productivity, whilst reducing costs. With this, it is perceived that the jobs within these organizations that are considered subject to ‘routine’, or repetitive and mundane tasks,

StanceXplore: Visualization for the Interactive Exploration of Stance in Social Media

The use of interactive visualization techniques in Digital Humanities research can be a useful addition when traditional automated machine learning techniques face difficulties, as is often the case with the exploration of large volumes of dynamic—and in many cases, noisy and conflicting—textual data from social media. Recently, the field of stance analysis has been moving from a predominantly bin

Röd Stjärna över Sverige. Folkrepubliken Kina som resurs i den svenska vänsterradikaliseringen under 1960- och 1970-talen

The aim of this study is to assess and analyze the image of revolutionary China in the eyes of Swedish leftwing travelers and activists during the heyday of Maoism, and how these traveler’s and activist’s reports and texts were used to promote friendship activism with China. Of particular interest is how the euphoric view of China in the west, during the Cultural revolution, was promoted and also

New Paradigms in Telemedicine: Ambient Intelligence, Wearable, Pervasive and Personalized

After decades of development of information systems dedicated to health professionals, there is an increasing demand for personalized and non-hospital based care. An especially critical domain is cardiology: almost two third of cardiac deaths occur out of hospital, and victims do not survive long enough to benefit from in-hospital treatments. We need to reduce the time before treatment. But sympto

Film Funding Developments in the EU: Effects of public film support on a small national cinema (invited paper presentation)

In the cinemas of small European nations, infrastructural support systems aimed at endorsing and strengthening audiovisual production, tend to play an increasingly pivotal role. Since additional systems have been added, with the intent to, for instance, encourage co-production or to attract filming and post-production work to assorted places – and always coming with various provisions attached – o

A Methodology for Measurements of Basic Parameters in a xDSL System

In order to qualify a subscriber loops for xDSL transmission, basic parameters like transfer function, scattering parameter S11 and characteristic impedance should be known. The aim of this paper is to present a test methodology for measurements of these basic parameters. The characteristic impedance is measured by open/short method and it is compared with the terminated measurement method defined

Managing risks in supply chains - an article review and Appendix

Background: A number of trends during the last decade, like globalisation, outsourcing, single sourcing, leanness and agility, have made the supply chain more vulnerable and “supply chain risk management” has become a research area of its own. Objective: To characterize the existing scientific knowledge and scientific knowledge creation within supply chain risk management as it is presented in the

Multimodal transportation in Eastern Europe: a Ukrainian legislative perspective

Multimodal transportation in the European continent is an integral part of cross border trade and in particular the use of sea and river carriers. The phenomenon of short sea shipping has reached a level of importance of which all European states must take cognisance. One of the policies associated with this issue is the development of the motorways of the sea. While Ukraine is not yet a part of t

A Mean-Variance Based Index for Dynamic Context Data Lookup

A primary functionality of context aware applications is the retrieval of different types of context data from various context sources and adapting their behavior accordingly. In order to facilitate context aware application development, a context aware middleware must provide an effective context data management and lookup strategy. The use of a traditional index for indexing dynamic context data

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Popular Abstract in Swedish Som ett skepp uti vilda havet, den kristna församlingen i ärkebiskop Laurentius Petris verk I 1593 års Uppsala mötes "förening om läran, ceremonier och kyrkotukt" finns följande avsnitt : Thernäst bejake och vederkännes vi oss alldeles vele holle vidh the Apostoliske, Niceniske och Athanasii symbola, såsom och vidh then äldste, rätte och oförrandrede Ausburgiske confeThe aim of this thesis is to present the ecclesiology of Laurentius Petri, a former student at Wittenberg who was archbishop of Uppsala from 1531 to his death 1573. He had a decisive role in the founding of the Church of Sweden, especially through his Swedish Church Ordinance(1571). Nevertheless most of his seventy-three writings are little known and have been rarely studied. Chapter one st