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Background and purpose: To evaluate the efficacy and safety of boron neutron capture therapy (BNCT) for glioblastoma multiforme (GBM) using a novel protocol for the boronophenylalanine-fructose (BPA-F) infusion. Patient and methods: This phase II study included 30 patients, 26-69 years old, with a good performance status of which 27 have undergone debulking surgery. BPA-F (900 mg BPA/kg body weigh

External Thermal Insulation Composite Systems (ETICS) represent a popular modern facade for reducing energy consumption, particularly in retrofit applications. Insulation - typically in the form of either EPS (expanded polystyrene) or mineral wool - is applied to the exterior of buildings using mortar adhesive, and then coated with a final layer of sand-cement render and glass fibre reinforcement.

On Zn-polluted soils, populations of the ectomycorrhizal basidiomycete Suillus bovinus exhibit an elevated Zn tolerance when compared to populations on non-polluted sites. To elucidate the mechanism of Zn tolerance, the time-course of Zn uptake was studied in isolates with contrasting Zn tolerance. Unidirectional fluxes and subcellular compartmentation of Zn were investigated through radiotracer f

AIMS: Catheter ablation is considered the treatment of choice for many tachyarrhythmias, but convincing 'real-world' data on efficacy and safety are lacking. Using Swedish national registry data, the ablation spectrum, procedural characteristics, as well as ablation efficacy and reported adverse events are reported. METHODS AND RESULTS: Consecutive patients (≥18 years of age) undergoing catheter a

Energy security, climate change and air pollution are all motivations for further development of fuel cells. Still, technical problems relating to water management, continue to hinder the marketability of polymer electrolyte fuel cells (PEFCs). The impact of dynamic contact angle (CA) boundary conditions, according to the Kistler model, is evaluated in this paper with the VOF approach, focusing on

Two electrotechnologies: pulsed electric fields (PEF) and moderate electric field (MEF) in combination with vacuum impregnation of glycerol as cryoprotectant were used to increase the freezing tolerance of rocket leaves. Rocket leaves were treated with PEF using a nominal field strength of 1200 V/cm or MEF at different combinations of voltage and frequency. Leaves were then immersed in a glycerol

Simple but robust approaches were used to reveal the quantitative and statistically significant influence of the Southern Oscillation Index (SOI) on monthly precipitation at five stations distributed over South Korea and Fukuoka, Japan. The monthly precipitation data were transformed into non-exceedence probability time series. SOI is classified into five categories. Correlation between the catego

Electronic coherence signatures can be directly identified in the time–frequency maps measured in two-dimensional electronic spectroscopy (2DES). Here, we demonstrate the theory and discuss the advantages of this approach via the detailed application to the fast-femtosecond beatings of a wide variety of electronic coherences in ensemble dimers of quantum dots (QDs), assembled from QDs of 3 nm in d

Small-angle X-ray scattering tensor tomography, which allows reconstruction of the local three-dimensional reciprocal-space map within a three-dimensional sample as introduced by Liebi et al. [Nature (2015), 527, 349-352], is described in more detail with regard to the mathematical framework and the optimization algorithm. For the case of trabecular bone samples from vertebrae it is shown that the

Abstract in UndeterminedWe suggest a method of analyzing the sustainability conditions for forestry from three major realms: environmental, social, and economic. The tools and methods were tested at sites in Sweden. Assessments were made for the long-term sustainability concerning the impact of present management practices on the balances of nutrients in monocultures and mixed-species stands. In t

The concept of sharing is commonly employed in brand narratives of platform-based start-ups to recruit users. This paper examines sharing as a brand ideology and how it is enacted by companies in the startup phase of business. As the sharing start-ups’ business model is dependent on transaction fees generated on the platforms, traction (i.e. a high volume of users) is critical for success. By anal

Glaciers are one of the main sources of freshwater in cold regions. The glacier melting process can significantly impact the glacier mass balance (GMB) and contribute a large amount of runoff in cold regions. This study applied the recently developed semi-distributed glacio-hydrological conceptual model (FLEXG) to understand the glacier melting process and the effect of topography on GMB in the To

We consider a multiqubit system of atoms or ions with two computational ground states and an interacting excited state in the so-called blockade regime, such that only one qubit can be excited at any one time. Examples of such systems are rare-earth-ion-doped crystals and neutral atoms trapped in tweezer arrays. We present a simple laser excitation protocol that yields a complex phase factor on an

This thesis consists of five chapters which focus on panel data theory. Four of them analyze explicit panel data models and one chapter deals with time series forecasting model, where external panel data help us estimate unobserved explanatory variables. The broad topics discussed in the thesis include i) simplification of distribution of a statistical test under double asymptotics, ii) eliminatio

Can the economic legacy of highly skilled groups persist long after they were uprooted from their homelands? To answer this question, we study long-term sub-national development in Turkey after the mass expulsions of the Armenian and Greek communities of the Ottoman Empire in the early 20th century. Since these events led to an almost complete and permanent removal of both communities from Turkey

The viability of wild bee populations and the pollination services that they provide are driven by the availability of food resources during their activity period and within the surroundings of their nesting sites. Changes in climate and land use influence the availability of these resources and are major threats to declining bee populations. Because wild bees may be vulnerable to interactions bet

The Proton Exchange Membrane (PEM) fuel cell has been investigated for a long time because it has a high power density, low emission, wide choice of fuel sources, etc. However, the performance of a stack of PEM cells degrades with respect to that of a single cell. This is mainly due to the introduction of the manifold in which supplies the reactants to individual cells. The manifold can induce an