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INTRODUCTION: Synaptic dysfunction and loss are pathological hallmarks of neurodegenerative diseases. Neuronal pentraxin 2 (NPTX2), a presynaptic protein involved in synaptic plasticity, has been linked to cognitive decline in Alzheimer's disease (AD) and other neurodegenerative disorders. METHODS: We developed and validated a novel single molecule array (Simoa) for NPTX2 in cerebrospinal fluid, w
ACTA ARCHAEOLOGICA LUNDENSIA SERIES IN 8°, No. 72 ACTA ARCHAEOLOGICA LUNDENSIA SERIES IN 8°, No. 72 Bygd, by och bostad runt Uppåkra Landskapet med sin centralplats Redaktör Mats Roslund uppåkrastudier 13 Tryckt med bidrag från Ebbe Kocks Stiftelse. © Institutionen för Arkeologi och Antikens Historia Grafisk form: Stilbildarna i Mölle/Frederic Täckström Omslagsbild: ”Geographisk charta öfwer härti
Germany is generally considered to be a country that is free trade friendly and had, at the start of the TTIP negotiations, a majority in favour of TTIP. Now however, Germany has amongst the lowest levels of public support of TTIP of all EU member states, while a majority at the same time remain positive of international trade and even increased trade with the US. Previous studies have shown that
Parallel trade in goods is generally viewed as a positive phenomenon within the EU as a consequence of the principle free movement of goods: When traders buy goods in one part of the common market at a low price and transfer it to a higher priced area, allowing them to undercut those prices, then this will enhance competition, drive down prices and give consumers more choice- an overall positive e
Introduction: Beverage consumption is a modifiable risk factor for type 2 diabetes (T2D), but there is insufficient evidence to inform the suitability of substituting 1 type of beverage for another. Objective: The aim of this study was to estimate the risk of T2D when consumption of sugar-sweetened beverages (SSBs) was replaced with consumption of fruit juice, milk, coffee, or tea. Methods: In the
The geochemistry of the metavolcanic rocks from the Granjeno Schist in northeastern Mexico indicates an origin in different tectonic environments: mid-ocean ridge and ocean island. High ratios of Hf/Th and Th/Nb (4.4-14 and 0.08-0.15), low ratios of LaN/YbN and LaN/SmN (0.74-1.7 and 0.60-1.4) and depleted LREE patterns in metabasalt display mid-ocean ridge characteristics. In contrast, the pattern
Dynamic glucose enhanced (DGE) chemical exchange saturation transfer (CEST) MRI is an emerging imaging technique that provides a molecular-specific type of image contrast, based on magnetic labelling of exchangeable protons. The technique enables the use of biodegradable sugars as contrast agents, and such compounds are believed to have less side effects than conventional MRI contrast agents. Howe
Vegetation productivity is a critical indicator of global ecosystem health and is impacted by human activities and climate change. A wide range of optical sensing platforms, from ground-based to airborne and satellite, provide spatially continuous information on terrestrial vegetation status and functioning. As optical Earth observation (EO) data are usually routinely acquired, vegetation can be m
Multidrug-resistant Pseudomonas aeruginosa is an increasing clinical problem worldwide. The aim of this study was to describe the first outbreak of a Verona integron-borne metallo-ß-lactamase (VIM)-2-producing P. aeruginosa strain in Sweden and its expansion in the region. A cluster of multidrug-resistant P. aeruginosa appeared at two neighbouring hospitals in 2006. The isolates were characterized
C-reactive protein (CRP)/Albumin ratio (CAR) seems to mirror disease severity and prognosis in several acute disorders particularly in elderly patients, which we aimed to study. As method we use a prospective study design; the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS; n = 912, women 50%; mean age 70 years, baseline 2001 and 2004, median follow-up 15.0 years, end of fo
Predicting live birth after the first IVF/ICSI treatment is challenging, as many factors may interact to affect IVF/ICSI outcomes. Adenomyosis is one factor that impacts live birth rates. Machine learning algorithms have been shown valuable for detecting complex dependencies and predicting outcomes in different clinical settings. We aimed to develop a prediction model for live birth after IVF/ICSI
Meddelanden från HT-biblioteken | februari 2025 Meddelanden från HT-biblioteken | februari 2025 Publicerad den 15 februari 2025 Foto: Sarah Giboni I denna månads nyhetsbrev informerar vi om LU:s nya bibliotekssöktjänst Finn som ska lanseras till hösten. Vi informerar också om ett nytt avtal för inköp av tryckt litteratur, en introduktion till EndNote och, i vanlig ordning, om våra öppna laboration
https://www.htbibl.lu.se/article/meddelanden-fraan-ht-biblioteken-februari-2025/ - 2026-07-11
The electrochemical communication between microorganisms and electrodes has substantial implications both for basic understanding of biological electron transfer as well as in diverse applications, such as, microbial electrochemical system (MES), microbial biosensors and in production of valuable chemicals. In these systems the extracellular electron transfer (EET) from microbial metabolism to ele
Background and AimsThe island of Gotland in the Baltic Sea has had no contact with surrounding continental areas since the withdrawal of the Weichselian ice sheet at approx. 17 ka BP. Plants present on Gotland must have arrived by long-distance dispersal, so populations are expected to exhibit reduced levels of genetic diversity compared with populations on surrounding mainlands. However, orchids
BackgroundTumour deposits are a prognostic factor for overall survival and distant metastasis in lymph node-negative colorectal cancer. However, the current TNM staging system does not account for the presence of tumour deposits in lymph node-positive colorectal cancer, or for the presence of multiple deposits. This study aimed to investigate the prognostic effect of tumour deposit count in patien
