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Many water treatment processes used to improve the quality of drinking- and wastewater directly or indirectly affect, or are affected by, the activity of microbes. These activities can improve water quality, presenting sustainable alternatives to mechanical or chemical processes. As water is distributed, it is also changed by microbes. Harnessing the potential of microbes to improve water quality

Title: Rules, roles and risks- A study on occupational health and safety in the construction sector Author: Tova Westerlund Supervisor: Radhlinah Aulin Examiner: Anne Landin Aim & goal: The purpose of this report has been to investigate occupational health and safety risks in the construction sector, how responsibility roles relate to these risks, and the impact of Arbetsmiljöverkets regulatio

The first years of life are a critical period of development, and circumstances during this period can affect individuals throughout life. But to what extent do disadvantaged circumstances in childhood affect individual wellbeing in later life and for whom? Can interventions in childhood break adversity over the life course? For whom are interventions most effective and why? This thesis aims to in

Savanna ecosystems of the Sahel are heavily affected by climate change, leading to drier subtropical regions. These ecosystems play a fundamental role in food security of the region, so that an improved understanding of how these ecosystems are affected by these weather events is thereby critical. Several studies have assessed the herbaceous production level, dynamics during the rainy season, and

This study explores the use of manganese ore, iron-carbon particles (Fe-C), and gravel as anode fillers in electroactive constructed wetlands (ECWs) to treat wastewater containing pharmaceuticals and personal care products (PPCPs) including ciprofloxacin (CIP), ofloxacin (OFL), and naproxen (NPX), while also assessing bioelectricity production. Although the presence of PPCPs reduced pollutant remo

Streptococcus pyogenes is one of the most common bacteria infecting humans. One of the factors contributing to the disease-causing properties is the secreted streptococcal cysteine proteinase, SpeB, which degrades several host proteins in connective tissue and circulation. SpeB activity depends on the transformation from an inactive precursor, zymogen, into a mature proteinase. We show that

Background: Ocrelizumab is a humanized anti-CD20 antibody with increased antibody-dependent cellular cytotoxicity compared with rituximab. This phase I/II study evaluated its safety and efficacy in patients with relapsed/refractory follicular lymphoma (FL) after prior rituximab therapy. Design and methods: Forty-seven patients were treated in three dose cohorts and received eight infusions every 3

The aecA and aecB loci map at 250 and 290 degrees, respectively, on the Bacillus subtilis chromosomal genetic map. The aecB locus has been proposed as the structural gene for aspartokinase II. From DNA sequence analyses and comparisons to the sequence of the aspartokinase II gene, it can be concluded that the structural gene for aspartokinase II is located close to sdh at 250 degrees and cannot be

Introduction: Although many surgeons have adopted the use of biologic and biosynthetic meshes in complex abdominal wall hernia repair, others have questioned the use of these products. Criticism is addressed in several review articles on the poor standard of studies reporting on the use of biologic meshes for different abdominal wall repairs. The aim of this consensus review is to conduct an evide

Authors of a recent paper demonstrate that, like ERMES (ER-mitochondria encounter structure) in fungal cells, PDZD8 (PDZ domain containing 8) tethers mitochondria to the ER in mammalian cells. However, identifying PDZD8 as a "functional ortholog" of yeast Mmm1 (maintenance of mitochondrial morphology protein 1) is at odds with the phylogenetic data. PDZD8 and Mmm1 are paralogs, not orthologs, whic

High northern latitudes are of special importance for the global carbon budget as they store large amounts of organic matter in the soil and are expected to be the most strongly affected by climate change. Here we investigate carbon exchange in the subarctic mountain birch forest growing on the limit where tree growth is possible. The study sites are located close to the Abisko village in norther

The type III receptor tyrosine kinase FLT3 is frequently mutated in acute myeloid leukemia. Oncogenic FLT3 mutants display constitutive activity leading to aberrant cell proliferation and survival. Phosphorylation on several critical tyrosine residues is known to be essential for FLT3 signaling. Among these tyrosine residues, Y842 is located in the so-called activation loop. The position of this t

In this dissertation, we discuss how buyers practice purchasing strategies in an asymmetric power situation favoring suppliers, and how their purchasing strategies practiced impact their purchasing power and buyer-supplier relationships. Organizations enter exchange relationships to access required resources not produced internally, and are exposed to uncertainty from not being able to fully contr