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An activity-based vocabulary for Voice Output Communication Aids (VOCAs) was designed and evaluated through a user-centred, iterative design process, using expressions from the Gothenburg Spoken Language Corpus as well as other recorded, natural conversations. The growth and development of the vocabulary, called Phrases, was closely linked to its evaluation. The iterative design process included p
Service discovery is central in pervasive middleware systems, built on top of the communication substrate using the more fundamental mechanisms for device discovery. In mobile pervasive systems devices come and go, and switch network frequently, demanding support for device discovery across heterogeneous networks. We present the design of a device discovery mechanism for the PalCom middleware that
The results of a search for an excited bottom-quark b* in pp collisions at root s = 7 TeV, using 4.7 fb(-1) of data collected by the ATLAS detector at the LHC are presented. In the model studied, a single b*-quark is produced through a chromomagnetic interaction and subsequently decays to a W boson and a top quark. The search is performed in the dilepton and lepton + jets final states, which are c
Hypoxic preconditioning is thought to rely on gene products regulated by hypoxia-inducible factor (HIF)-1. Here, we show that the HIF-1 target gene cyclin-dependent kinase inhibitor 1, p21(WAF1/CIP1), is essential for neuroprotection by hypoxic/aglycemic or erythropoietin preconditioning using wild-type and p21(WAF1/CIP1)-deficient neurons. Furthermore, overexpression of wild-type p21(WAF1/CIP1) o
We report the development of a high-level bacterial expression system for the Alzheimer's disease-associated amyloid beta-peptide (A beta), together with a scaleable and inexpensive purification procedure. A beta(1-40) and A beta(1-42) coding sequences together with added ATG codons were cloned directly into a Pet vector to facilitate production of Met-A beta(1-40) and Met-A beta(1-42), referred t
Rating scales are increasingly the primary outcome measures in clinical trials. However, clinically meaningful interpretation of such outcomes requires that the scales used satisfy basic requirements (scaling assumptions) within the data. These are rarely tested. The SF-36 is the most widely used patient-reported rating scale. Its scaling assumptions have been challenged in neurological disorders
Following the fragmentation of a 550 MeV u(-1)primary beam of Ni-58, time-and energy-correlated gamma decays from isomeric states in neutron-deficient nuclei in the 1f(7/2) shell have been identified using the GSI fragment separator in combination with the RISING Ge-detector array. The results on isomers in the mirror pairs Ti-43(22)21-Sc-43(21)22 (I-pi = 3/2(+) and 19/2(-)), Cr-45(24)21-Sc-45(21)
This doctoral thesis explores the implications of establishing tradable certificate schemes for improving energy efficiency (so-called ‘Tradable White Certificate’ [TWC] schemes). Carrying out different case studies, a set of complementary evaluation methods is applied in conducting ex-ante and ex-post evaluation studies. To analyse the attributes and complexities of TWC schemes, the thesis focuse
We have compared the predictions of ligand-binding affinities from several methods based on end-point molecular dynamics simulations and continuum solvation, i.e. methods related to MM/PBSA (molecular mechanics combined with Poisson-Boltzmann and surface area solvation). Two continuum-solvation models were considered, viz. the Poisson-Boltzmann (PB) and generalised Born (GB) approaches. The non-el
This paper investigates the gains harvested through base station cooperation in the up-link for a multi-user (MU) Multiple-Input Multiple-Output Orthogonal Frequency Division Multiplexing (MIMO-OFDM) system, operating in a real indoor environment. The base stations perform joint detection using an iterative receiver that carries out multi-user detection and channel estimation via soft information
A tree-ring-width chronology of Pinus tabulaeformis from Kalaqin, Inner Mongolia was developed using modern dendrochronological techniques. Based on the results of correlation function analysis, the total precipitation from the previous August to current July was reconstructed for 1771-2008 AD with an explained variance of 49.3%. The reconstruction correlated well with the dryness/wetness series d
The cliff-edge hypothesis introduces the counterintuitive idea that the trait value associated with the maximum of an asymmetrical fitness function is not necessarily the value that is selected for if the trait shows variability in its phenotypic expression. We develop a model of population dynamics to show that, in such a system, the evolutionary stable strategy depends on both the shape of the f
The 2009 Kidney Disease: Improving Global Outcomes (KDIGO) clinical practice guideline on the monitoring, management, and treatment of kidney transplant recipients is intended to assist the practitioner caring for adults and children after kidney transplantation. The guideline development process followed an evidence-based approach, and management recommendations are based on systematic reviews of
Title: HR Analytics for Competitive Advantage: Bringing organisational value while empowering the HR profession Authors: Elin Engsfelt & Louise Rosén Fång Supervisor: Rikard Larsson Problem definition: The HR profession has throughout history, and still has, a legitimacy problem, where the HR department typically becomes administrative support, rather than a strategic business partner. Purp
The Arctic faces massive challenges, and scholars estimate that parts of the Arctic are warming six times faster than the global mean. Consequently, the regions’ valuable resources are becoming more accessible due to climate change. These resources are argued as necessary for meeting global sustainable development challenges. Many scholars are additionally concerned that economic policy goals are
The Swedish government has set the goal of achieving carbon-neutrality by 2045. The production of cement currently accounts for 8% of CO2 emissions worldwide, with a similar figure also true of Sweden. A clear government strategy is therefore needed to work with and provide support to the cement industry for decarbonisation. The most developed pathway for cement decarbonisation in the literature i
The aim of the study at had was to explore the potential of Natural Capital Accounting (NCA) to integrate environment into business decision-making. In order to fulfill the aim, the research was split into three main parts. First, the existing views on what constitutes NCA were reviewed through a literature analysis of grey literature, and the working definition established. The study found that t
Separating valuable minerals from waste rock is an important step in the production of metals. This is for copper ore done through a process called flotation. A flotation series consists of tank cells in series where the minerals are collected in a froth on top of the cells. The level control of the flotation cells is important in order to be able to collect the froth. The first four flotation cel
Environmental tax measures have the potential to be great tools for achieving sustainable development goals in the EU. The different dimensions of sustainability need to be balanced in order to achieve sustainable development goals. In the EU, tax law has been focussed too much on the economic dimension, and too little on the environmental dimension, which could lead to environmental sustainabilit
