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Summary: Existing approaches to modelling antibody concentration data are mostly based on finite mixture models that rely on the assumption that individuals can be divided into 2 distinct groups: seronegative and seropositive. Here, we challenge this dichotomous modelling assumption and propose a latent variable modelling framework in which the immune status of each individual is represented along
Hairy cell leukemia is an uncommon hematologic malignancy characterized by pancytopenia and marked susceptibility to infection. Tremendous progress in the management of patients with this disease has resulted in high response rates and improved survival, yet relapse and an appropriate approach to retreatment present continuing areas for research. The disease and its effective treatment are associa
Desferrioxamine-B (DFOB) is a bacterial trihydroxamate siderophore and probably the most studied to date. However, the manner in which DFOB adsorbs at mineral surfaces and promotes dissolution is still under discussion. Here we investigated the adsorption and dissolution reactions in the goethite-DFOB system using both in situ infrared spectroscopic and quantitative analytical methods. Experiments
Two new carboxylate-containing polydentate ligands have been synthesized, the symmetric ligand 2,6-bis[N-(N-(carboxylmethyl)-N-((1-methylimidazol)methyl)amine)methyl]-4-methylphenolate (BCIMP) and the corresponding asymmetric ligand 2-(N-isopropyl-N-((1-aminomethyl)-4-methylphenol (ICIMP). The ligands have been used to prepare model complexes for the active site of the dinuclear nickel enzyme urea
The mobilization of fatty acids from rat and human fat cells is selective according to molecular structure, and notably carbon atom chain length. This study aimed at examining whether the release of individual fatty acids from triacylglycerols (TAG) by hormone-sensitive lipase (HSL) plays a role in the selectivity of fatty acid mobilization. Recombinant rat and human HSL were incubated with a lipi
These final results from DELPHI searches for the Standard Model (SM) Higgs boson, together with benchmark scans of the Minimal Supersymmetric Standard Model (MSSM) neutral Higgs bosons, used data taken at centre-of-mass energies between 200 and 209 GeV with a total integrated luminosity of 224 pb(-1). The data from 192 to 202 GeV are reanalysed with improved b-tagging for MSSM final states decayin
The review and Paper I present applications of economics to the use of alcohol. The review considers the demand for alcohol. The first paper also considers taxes and other alcohol policy measures, social costs and economic evaluations. In Paper II, an Almost Ideal Demand System Model is used for the study of the demand for alcoholic beverages in Sweden during the years 1985-1995. The results indi
New interactive information and communication technology (ICT) has opened up new possibilities in the field of distance education. The traditional distance education organisations are challenged by conventional universities who have developed into dual mode institutions using interactive ICT. This challenge from conventional universities may also involve a conceptual challenge - from distribution
Gluconobacter oxydans (ATCC 621) were permeabilized with toluene and then lyophilized. This crude enzyme preparation was used to reduce eleven ketones to (S)-alcohols with high enantiomeric excess (for most alcohols 93%-99% e.e.). The coenzyme NADH was regenerated either by adding a second enzyme, formate dehydrogenase, and its substrate, formate, or with 2-butanol as a second substrate for the G.
This paper critically examines Rwanda’s Gender Strategy for the Mining Sector through the lenses of Bacchi’s What is the Problem Represented to be (WPR) approach and feminist political ecology (FPE) concepts. Against the backdrop of Rwanda’s post-genocide development journey, the study investigates how gender (in)equality is problematised, (re)presented, and promoted within the context of res
Ecosocialist theorists increasingly call for nationalisation programmes to nationalise fossil fuel industry giants in order to orchestrate a just transition on a timetable compatible with pulling the emergency brake on climate collapse. Yet few such programmes exist. Synthesising utopian- and eco-socialist theoretical frameworks, this thesis uses class conflict informed participatory backcasting t
This thesis investigates the possibility of leveraging eBPF to audit containerized workloads to produce data equivalent to AppArmor auditing, with the goal of later using that data to automatically generate AppArmor profiles to protect those workloads. The report presents several challenges posed by the restrictive nature of eBPF as well as how these challenges were addressed in the implementation
This thesis studies organizational change in the peacebuilding organization the School for Peace. It asks the question: What shapes organizational change in the School for Peace? Being located in Israel’s only peace bubble, the School for Peace presents as an unusual case of peacebuilding in unique conditions. To understand reasons for change and evolvement of the organization’s practice – as well
This thesis investigates the narratives Icelandic politicians use to discuss crime, particularly focusing on themes of cultural purity and danger. The study aims to understand how these narratives influence public perception and policy. Politicians often frame crime as a significant threat to societal norms and values, using various rhetorical strategies to evoke emotions such as fear and urgency.
Denna avhandling handlar om teoretisk partikelfysik. Partikelfysik handlar om elementarpartiklar och hur dessa växelverkar med varandra, dvs vilka krafter som verkar mellan dem. Detta är hur materien ser ut på den minsta skala vi har kunnat studera experimentellt. Den teori som beskriver de starka, svaga och elektromagnetiska krafterna och de materiepartiklar som vi känner till, kvarkar och lepton
Constant volume combustion is studied, using a zero-dimensional model, which is a wide-ranging chemical kinetic simulation that allows a closed system of gases to be described on the basis of a set of initial conditions. The model provides an engine- or reactor-like environment in which the engine simulations allow for a variable system volume and heat transfer both to and from the system. The com
