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Parkinson's disease is the second most prevalent neurodegenerative disease, yet despite this, very little is known about the underlying cellular mechanisms. Initially it was thought to be a disease primarily involving loss of dopaminergic neurons in the substantia nigra pars compacta. Recent studies, however, have focused on observations that aggregated α-synuclein protein, the major component of
The aim of the study was to identify whether a ventilated cooling shirt was effective in reducing heat strain in hot climate. 8 female volunteers (age: 26±5 years; height: 165±7 cm; body weight: 58±9 kg) were exposed in heat (38 °C, 45 % RH) for 2 hours with simulated office work. In the first hour they were in normal summer wears (total thermal insulation 0.7 clo); in the second hour a ventilated
Simple and computer attractive models for calculating radiation properties are still needed. This paper gives correlations for the Planck and Rosseland means of the extinction and scattering coefficients for both cylindrically and spherically shaped soot particles. The means are valid for temperatures between 400 and 2400 K and particle radii between 0.001 and 0.5 mum. The errors of these means ar
IS har under många års tid begått fruktansvärda brott i deras ”kalifat”, framförallt mot etniska minoriteter och kvinnor. Deras agerande har av FN:s utredningskommission ansetts uppnå kriterierna för folkmord, krigsbrott och brott mot mänskligheten. Den här uppsatsen analyserar möjligheterna för det internationella straffrättssystemet att utreda och döma IS-medlemmar för de här brotten. Enligt teoISIS has committed horrible crimes to people in their “caliphate”, especially towards ethnic minorities and women. Their actions are according to the UN Independent Commission of Inquiry considered to constitute crimes against humanity, war crimes and genocide. This essay analyses the possibilities for the international criminal system to investigate and prosecute members of ISIS who have committe
Topology optimization is a powerful method for finding optimized designs for a variety of problems. In this work, thermo-mechanical problems are studied in particular and solved under transient conductive heat transfer using 2 materials plus void in the optimization. In the first part of the thesis, the theoretical background for a generic transient thermo-mechanical topology optimization problem
The biosynthesis of molecular species of phosphatidylethanolamine and phosphatidylcholine in isolated rat liver parenchymal cells was studied with [32P]phosphate and [3H]glycerol as precursors. Addition to the cells of albumin-bound oleic or linoleic acid resulted in the synthesis of high proportions of dioleoyl- or dilinoleoyl-phospholipids, especially from labeled glycerol. The fact that these s
In this paper we report on a facile, cost effective and environmental friendly green synthesis method of gold and silver nanoparticles (NPs) by using quercetin as reducing agent. The obtained NPs were characterized by transmission electron microscopy (TEM), energy dispersive spectroscopy (EDS), dynamic light scattering (DLS) and UV-Vis spectroscopy and parameters such as pH, ionic strength and tem
Although reports of pharmaceutical bioconcentration in aquatic organisms are increasing, less is known about trophic transfer in aquatic food webs. The bioaccumulation and trophodynamics of sertraline and fluoxetine, 2 selective serotonin reuptake inhibitors (SSRIs) frequently detected in aquatic environments, were tested by exposing constructed aquatic food chains to SSRIs under controlled labora
In the present study, the operation performance of an ultralow-temperature cascade refrigeration freezer is experimentally researched. The natural refrigerants R290-R170 are adopted as high-temperature and low-temperature fluids. The experimental test is conducted in a type laboratory with a dry bulb temperature of 32.0 °C and a wet bulb temperature of 26.5 °C. Different state monitors are set to
I contribute to an emerging politics of loss through an empirical analysis of temporalities of climate change loss and damage in Australia. How people temporalize climate change informs their conception of causality, designation of losses and damages, and political response. By drawing attention to the diversity of onto-epistemological understandings and characterizations of climate change loss an
Even if much is known regarding the effects of internet-delivered cognitive behaviour therapy (ICBT) for depression there are several topics that have not been studied. In this factorial design trial with 197 participants we investigated if clients in ICBT could select treatment modules themselves based on a selection of 15 tailored treatment modules developed for use in ICBT for depression. We co
Abstract Today it is very common that some person register a domain name that is identical or confusingly similar to a hallmark that is someone’s protected property. From the owners opinion this can result in a lost of company’s goodwill and there is risk that hallmark becomes powerless. Every physical and legal person can register someone’s protected hallmark as a domain name under top – level do
This work aims to investigate the breakup dynamics of the low-density gas and liquid interface during bubble formation in a microchannel flow-focusing device. A high-contrast interface tracking method is developed. After the neck motion analysis in radial and axial directions, the time domain criterion between the liquid squeezing stage and the free pinch-off stage is proved to be two orders of ma
Models on L3/Ln acquisition differ with respect to how they envisage degree (holisticvs. selective transfer of the L1, L2 or both) and/or timing (initial stages vs. development) of howthe influence of source languages unfolds. This study uses EEG/ERPs to examine these models,bringing together two types of bilinguals: heritage speakers (HSs) (Italian-German, n = 15) comparedto adult L2 learners (L1
BACKGROUND: Overactivity or contractures of the hamstring muscles in ambulatory children with cerebral palsy (CP) can lead to either a jump gait (knee flexion associated with ankle plantar flexion) or a crouch gait (knee flexion associated with ankle dorsiflexion). Hamstring lengthening is performed to decrease stance knee flexion. However, this procedure carries the potential risk of weakening hi
For polarization-resolved reflection experiments such as ellipsometry, not only is high reflectivity in a wide spectral range required for mirrors but also the quality of their polarization response is important. Furthermore, for VUV ellipsometry, optimal angles of incidence at the sample are between 45° and 60° with respect to the surface normal. In the best case, a setup should even allow variab
OBJECTIVE: To compare experts' perceived usefulness of audit filters from Ghana, Cameroon, WHO and those locally developed; generate context-appropriate audit filters for trauma care in selected hospitals in urban India; and explore characteristics of audit filters that correlate to perceived usefulness.DESIGN: A mixed-methods approach using a multicentre online Delphi technique.SETTING: Two large
X-ray phase-contrast imaging is a powerful technique that allows great resolving power for low absorbing samples, such as biological tissue. This method relies on measuring the phase shift induced by the sample instead of the absorption traditional radiography relies on. This phase shift is measured as an intensity modulation at the detector and by using various algorithms one can obtain informati
