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BACKGROUND: Prognostication of recovery in patients who are unconscious following cardiac arrest can be guided by concentrations of brain injury biomarkers in the blood. The optimal biomarker and cutoff concentrations for the prediction of outcome remain unknown. In this study, we aimed to evaluate which biomarker of brain injury is most accurate for predicting functional outcome after cardiac arr
Vi har under de senaste åren upplevt en allt mer intensifierad debatt kring den svenska lagstiftningen mot supportervåld och huliganism. Många är de som menar att vår nuvarande lagstiftning saknar en direkt verkan mot problemet och att förändring på området måste ske. Vår svenska lagstiftning är likt många andra länders lagstiftningar uppbyggd kring tillträdesförbudet. Det är den mest centrala ochThis thesis will discuss the legal perspective of the problem with hooliganism in Sweden. Is the Swedish legislation sufficient enough to withstand and combat this slowly on-the-rise problem that we have with football violence? This question will be answered as well as what actions may be taken to rationalize and make the legislation more efficient. The Swedish legislation is focused around the eq
Background: The humerus is the second most common long-bone site of metastatic bone disease. We report complications, risk factors for failure, and survival of a large series of patients operated on for skeletal metastases of the humerus. Materials and methods: This study was based on 208 patients treated surgically for 214 metastatic lesions of the humerus. Reconstructions were achieved by intram
BACKGROUND: In Phase II/III trials, administration of quadrivalent human papillomavirus (HPV) (types 6/11/16/18) L1 virus-like-particle vaccine was highly effective in preventing HPV6/11/16/18-related cervical intraepithelial neoplasia and non-invasive cervical cancer in women aged 16-26 years who were naïve to these HPV types at enrollment. However, the makeup and extent of catch-up vaccination p
This study describes a new method for the fixation of titanium hip stem prostheses based on interdigitation of irregularly shaped porous titanium granules onto bone tissue. The granules were distributed into the prepared femoral cavity using a vibrating tool, and the stem was vibrated and tapped into the bed of granules. In this pilot study, 5 patients were followed between 9 and 15 years. The cli
A generally accepted way of building passive houses has been to have small windows facing north and large windows to the south. This is to minimize losses on the north side while gaining as much solar heat as possible on the south. ln spring 2001, 20 terraced houses were built outside Gothenburg partly in this way. The indoor temperature is kept at a comfortable level by passive methods, using sol
Popular Abstract in Swedish Cancerceller är celler som på grund av mutationer, felaktigheter i cellernas DNA, har erhållit förmågan att dela sig ohämmat. Celler behöver tillgång till syre och näring för att överleva, vilket levereras via kroppens blodkärl. Den snabba tillväxten av tumörvävnad leder dock till att befintlig blodtillförsel inte räcker till och delar av tumörerna drabbas därför av syrThe transition from normal into malignant cells with acquired uncontrolled growth is a process where cancer cells viciously develop adaptive strategies to overcome microenvironmental and metabolic stress. Hypoxia, or deficient oxygen supply, is a common feature of the expanding tumor which alters cell metabolism and consecutively causes lowered intracellular pH. To alleviate hypoxic and acidotic s
BACKGROUND: Polymorphisms of the vitamin D receptor (VDR) gene have been implicated in the genetic regulation of bone mineral density (BMD). However, the clinical impact of these variants remains unclear.OBJECTIVE: To evaluate the relation between VDR polymorphisms, BMD, and fractures.DESIGN: Prospective multicenter large-scale association study.SETTING: The Genetic Markers for Osteoporosis consor
In contrast to acute lymphoblastic leukemia in children, adult cases of this disease are associated with a very poor prognosis. In order to ascertain whether the frequencies and patterns of submicroscopic changes, identifiable with single nucleotide polymorphism array analysis, differ between childhood and adult acute lymphoblastic leukemia, we performed single nucleotide polymorphism array analys
There is a need for large trials that test the clinical effectiveness of interventions in the field of perioperative medicine. Clinical outcome measures used in such trials must be robust, clearly defined and patient-relevant. Our objective was to develop standards for the use of clinical outcome measures to strengthen the methodological quality of perioperative medicine research. A literature sea
Under 1680-talet trädde Sophia Elisabet Brenner fram som poet och blev snart känd och uppskattad för sina dikter vid olika tillfällen i livet. Tillfällesdiktningen var en flexibel genre som gav henne möjligheten att resonera om tidens aktuella frågor, till exempel kvinnans ställning i äktenskap och samhälle eller värderingen av det som var gammalt och fornt och det som var nytt. Hennes rykte spred
Computing systems are becoming more and more complex and powerful. It is nowadays not uncommon to run several server applications on the same physical platform. This gives rise to a need for resource reservation techniques, so that administrators may prioritize some tasks, or customers, over others. This thesis gives an introduction to the Linux kernel 2.6 task scheduler, and scheduling related op
Monitoring and regulation of fermentations is of a paramount industrial and academic importance in order to keep conditions optimal during the entire process. Established techniques employed today include HPLC and spectrophotometry, which both have the disadvantage that broth samples have to be drawn from the fermentor and that they often require sample pre-treatment. The objectives of this study
The purpose of this investigation was to describe the clinical spectrum of invasive Fusobacterium necrophorum infections and Lemièrre's syndrome, to examine the role of underlying thrombophilia and concomitant mononucleosis in Lemièrre's syndrome, and to describe thromboembolic complications. Patients with invasive F. necrophorum infections were identified either prospectively or retrospectively t
Background: We have developed a rapid method, based on lamellar body counts (LBC) on gastric aspirate, for identifying newborns who will develop respiratory distress syndrome with a need for surfactant supplementation. Objective: We set out to test whether it was possible to improve the outcome when used in a clinical trial. Methods: We randomly assigned 380 infants born at 24-29 weeks' gestation
The aim of this cross-sectional study was to investigate the prevalence of overweight and obesity in children and adolescents (6-16 years), and relationships between being overweight and sleep, experiencing of fatigue, enjoyment of school, and time spent in watching television and in sitting at the computer. Trained school nurses measured the weight and height of 2891 children aged 6, 7, 10, 14, a
