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Given that Alcohol Use Disorder (AUD) is clinically heterogeneous, can we, in a large epidemiological sample using public registries, identify clinical features of AUD cases in biological and step-fathers that index, respectively, genetic and familial-environmental risk for AUD in their offspring? From all father-offspring pairs where the father had AUD and the offspring was born 1960–1990, we ide
With the increased concern about energy security, air pollution and global warming, the possibility of using polymer electrolyte fuel cells (PEFCs) in future sustainable and renewable energy systems has achieved considerable momentum. A computational fluid dynamic model describing a straight channel, relevant for water removal inside a PEFC, is devised. A volume of fluid (VOF) approach is employed
I den andra delen av avhandlingen introduceras några konkreta förslag på tillämpningar av paleontologisk kunskap generellt, och forskningsresultat om fossil från Kristianstadsområdet specifikt, som kan användas i undervisning från förskola till gymnasieskola med undervisningsförslag inom de tre områdena; fossil och dinosaurier i förskolan, tidslinjer för utveckling av tidsmedvetenhet samt geovetenThis thesis is thematically divided into two sections: Part1 presents studies related to the palaeoenvironments,palaeoecology and palaeobiogeography of the LateCretaceous (Campanian) faunas from the KristianstadBasin of southern Sweden; Part 2 reports on applicationsof palaeontological research for science education inschools.Part 1 was based on personally conducted fieldworkand biostratigraphical
A search for doubly charged Higgs bosons with pairs of prompt, isolated, highly energetic leptons with the same electric charge is presented. The search uses a proton–proton collision data sample at a centre-of-mass energy of 13 TeV corresponding to 36.1 fb - 1 of integrated luminosity recorded in 2015 and 2016 by the ATLAS detector at the LHC. This analysis focuses on the decays H± ±→ e±e±, H± ±→
Higgsinos with masses near the electroweak scale can solve the hierarchy problem and provide a dark matter candidate, while detecting them at the LHC remains challenging if their mass splitting is O(1 GeV). This Letter presents a novel search for nearly mass-degenerate Higgsinos in events with an energetic jet, missing transverse momentum, and a low-momentum track with a significant transverse im
The sector for private domestic services in Sweden has grown rapidly since the RUT tax deduction was introduced in 2007. Already in the government proposition (2006/07:94) it was suggested that services provided by the expanding market would come to replace parts of the publicly funded elderly care, thus marking a shift in the organisation of care in the welfare state. Today we begin to see the ef
We study a simple extension of the Standard Model featuring a dark sector with an ultralight pseudo-Nambu-Goldstone boson as a dark matter candidate. We focus on the mass range O(10-20-10-10) eV, relevant for strong gravity applications, and explore its production and evolution in the early Universe. The model is formulated in such a way that dark matter does not couple directly to photons or othe
Objectives: To determine the impact of the COVID-19 pandemic on the incidence rates of infection and islet autoimmunity in children at risk for type 1 diabetes. Methods: 1050 children aged 4 to 7 months with an elevated genetic risk for type 1 diabetes were recruited from Germany, Poland, Sweden, Belgium and the UK. Reported infection episodes and islet autoantibody development were monitored unti
OBJECTIVE: To develop a prediction model for major morbidity and endocrine dysfunction after CP which could help in tailoring the use of this procedure.SUMMARY BACKGROUND DATA: Central pancreatectomy (CP) is a parenchyma-sparing alternative to distal pancreatectomy for symptomatic benign and pre-malignant tumors in body and neck of the pancreas CP lowers the risk of new-onset diabetes and exocrine
This paper presents a detector developed to protect the ESS spallation target. The detector is installed to receive a proton beam that has a peak current of 62.5 mA, an average power of 5 MW, and energy up to 2 GeV. It is designed to detect any part of the proton beam that goes outside a defined aperture, which is deemed as an errant beam condition. This detector is mainly used for machine protect
Objective: To investigate real-world effectiveness of tumor necrosis factor inhibitors (TNFi) in patients with axial spondyloarthritis (axSpA) and the association with (i) treatment line (second and third TNFi-series) and (ii) reason for withdrawal from the preceding TNFi [lack of efficacy (LOE) vs adverse events (AE)]. Methods: Prospectively collected routine care data from 12 European registries
Objectives: The use of magnetic resonance imaging (MRI) is safe from a long-term perspective since there are no known cumulative risks for patients or personnel. However, the technique comes with several acute risks associated with the powerful electromagnetic fields that are necessary to produce medical images. These risks include, among other things, a projectile hazard, loud noise, and the risk
Finding direct records of the ancient Earth's atmosphere is key to understand the evolution of the entire planet. Nevertheless, such records are scarce, and only a few geological samples with preserved paleo-atmospheric signatures are available today. In this study, we analyzed noble gases contained in shocked granitic and volcanic rocks collected across the 380 Ma-old Siljan impact structure (in
In the CONVINCE trial, the primary analysis demonstrated a survival benefit for patients receiving high-dose hemodiafiltration (HDF) as compared with high-flux hemodialysis (HD). A secondary objective was to evaluate effects on health-related quality of life (HRQoL); assessed in eight domains (physical function, cognitive function, fatigue, sleep disturbance, anxiety, depression, pain interference
Even though energy-efficient technologies are well developed, the behaviour of building occupants plays an important role in the search for the optimum level of energy efficiency. In academic literature, however, very few studies have used psychological theories to understand individuals’ drivers of energy use behaviour when interacting with energy-efficient technologies. Specifically, there are n
Differential and double-differential distributions of kinematic variables of leptons from decays of top-quark pairs (tt¯) are measured using the full LHC Run 2 data sample collected with the ATLAS detector. The data were collected at a pp collision energy of s = 13 TeV and correspond to an integrated luminosity of 140 fb −1. The measurements use events containing an oppositely charged eμ pair and
Background - Correct blood group typing is the cornerstone of transfusion medicine. In patients whose gastrointestinal wall is compromised, bacterial enzymes can cause deacetylation of blood group A, converting N-acetylgalactosamine to galactosamine, which resembles the B-defining galactose. This acquired B (acqB) phenomenon, first described 1959, can lead to blood grouping errors. Herein, we expl
Introduction: Commissioning, calibration, and quality control procedures for nuclear medicine imaging systems are typically performed using hollow containers filled with radionuclide solutions. This leads to multiple sources of uncertainty, many of which can be overcome by using traceable, sealed, long-lived surrogate sources containing a radionuclide of comparable energies and emission probabilit
