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The major aim of this study was to investigate the CYP3A4 metabolism and polarized transport of ropivacaine and its metabolite 2',6'-pipecoloxylidide (PPX) in tissue specimens from the human small and large intestine. Ropivacaine has been shown to be effective in the treatment of ulcerative colitis in human colon. This study was conducted using a modified Ussing-chamber technique with specimens fr
Abstract in Undeterminedhe atJthor dlscusses the relalionship betwccn peaplc and animals in a lime perspective of millcllnia. The starting point is the pre-Chri stian. $can dinavl:m. animal graves ofJogs and hoJ'SCs. the Saami hear-graves, as wdl as animal burials urmodern time. TIle occurrence ofanimal graves In pre Christian time and the wide mnge ofways to dispose of human and animal bodics c
This research explores the interplay between strategic communication and legitimacy in United Nations (UN) peacekeeping missions, focusing on the United Nations Stabilization Mission in the Democratic Republic of Congo (MONUSCO) and addresses the challenge of maintaining and establishing legitimacy through strategic communication during crises. The study specifically investigates the use of strate
The original aim for this case study was to look at how two synonymous lexemes, feminine and womanly, have varied in meaning over time in both British and American literature and also, to see if there was a difference in the usage of the lexemes depending on whether the author was male or female. As can be read in Lyons (1995: 60), lexemes like feminine and womanly would be called near-synonyms in
A method based on three-phase hollow fiber liquid phase microextraction was developed and successfully applied to aerosols for the analysis of lignin pyrolysis acids such as syringic acid, vanillic acid and p-salicylic acid. Important parameters related to extraction process like organic solvent for membrane phase, tri-n-octylphosphine (TOPO) oxide contents in organic solvent, stirring speed, extr
Three young men were trapped in a car at the bottom of a canal at two meters depth, after losing control of their vehicle. They were brought up by rescue divers and found in cardiac arrest. One of three patients had return of spontaneous circulation (ROSC), at 47 min after the accident. This sole survivor had the longest submersion time of the three and he received continued mechanical chest compr
Denna uppsats studerar skiljeförfarandemekanismen i Convention of the Settlement of Investment Disputes Between States and Nationals of Other States (ICSID-konventionen) och hur den används i bilaterala investeringsavtal (BITs). Ämnet analyseras utifrån Third World Approach to International Law (TWAIL), vars synsätt utgår från att det finns en strukturell orättvisa i folkrätten och en dominans av
Tourism is considered one of the main driving forces of economic growth. At the same time, micro and small businesses play a vital role in the development of the tourism sector as a supply side. Also, the development of entrepreneurial activity directly depends on internal and external financial resources. So, this qualitative case study investigates the access to external finance, concessional lo
Generation Z [Gen Z] har till skillnad från tidigare generationer ett behov att bli förstådda av företag för att ha en positiv inställning till deras kommunikation. Detta, kombinerat med en mer komplex tid att hantera en digital kundupplevelse, gör det svårt för företag att nå ut till målgruppen på sociala medier. Denna studie syftar därav till att gå på djupet för att förstå hur Gen Z uppfattar fGeneration Z [Gen Z], unlike previous generations, has a need to be understood by companies in order to have a positive attitude towards their communication. This, combined with a more complex time managing a digital customer experience, makes it difficult for companies to reach the target audience on social media. This study therefore aims to go in depth to understand how Gen Z perceives companie
Soil contamination is a widespread problem and action needs to be taken in order to prevent damage to the groundwater and the life around the contaminated sites. In Sweden, it is estimated that more than 80,000 sites are potentially contaminated, and therefore, there is a demand for investigations and further treatment of the soil. In this paper, we present the results from a methodology applied i
Aims: Iron deficiency (ID) is a common co-morbidity in heart failure (HF), associated with impaired functional capacity, poor quality of life and increased morbidity and mortality. Treatment with intravenous (i.v.) ferric carboxymaltose (FCM) has shown improvements in functional capacity, symptoms and quality of life in stable HF patients with reduced ejection fraction. The effect of i.v. iron sup
Imprinted genes, giving rise to parent-of-origin effects (POEs), have been hypothesised to affect type 1 diabetes (T1D) and rheumatoid arthritis (RA). However, maternal effects may also play a role. By using a mixed model that is able to simultaneously consider all kinds of POEs, the importance of POEs for the development of T1D and RA was investigated in a variance components analysis. The analys
Serum levels of Anti-Mullerian Hormone (AMH) have been shown to be biomarker for prediction of the quantitative aspects of ovarian reserve. On the male side, sperm chromatin structure assay (SCSA) DNA fragmentation index (DFI) has been demonstrated to be an important predictor of outcomes in standard IVF procedures but to less degree in intracytoplasmic sperm injection procedures (ICSI). The purpo
The aim was to describe food intake over time in children and adolescents, with respect to age and gender. The present study was a repeated cross-sectional study using self-reported data from a health questionnaire. Data were collected from the School Health Services in south-east Sweden from 44 297 students, 10, 13-14 and 16 years of age, 48 % girls and 52 % boys from 2009/2010 to 2015/2016. Repo
Occupational balance promotes health, knowledge about occupational balance among older workers is important. This qualitative study aimed to describe occupational balance among older workers in Sweden. Six focus groups and two individual interviews were conducted with 26 workers, aged 65 years and older. The findings showed that drawing on abilities and resources, a harmonious mix of occupations,
A search for a heavy neutral Higgs boson, A, decaying into a Z boson and another heavy Higgs boson, H, is performed using a data sample corresponding to an integrated luminosity of 36.1 fb−1 from proton–proton collisions at s=13 TeV recorded in 2015 and 2016 by the ATLAS detector at the Large Hadron Collider. The search considers the Z boson decaying to electrons or muons and the H boson into a pa
