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Syftet med denna uppsats är att, genom att använda en rättsdogmatisk metod och ett kritiskt perspektiv, utreda huruvida en sådan processuell preklusionsregel som föreslagits i SOU 2015:12 Överprövning av upphandlingsmål m.m. bör införas i upphandlingslagarna. Den föreslagna lagen skulle innebära att en part till stöd för sin talan får åberopa nya omständigheter och bevis först i kammarrätten endasThe purpose of this essay is to, by using a legal dogmatic method and a critical perspective, investigate whether a procedural rule of preclusion as proposed in SOU 2015:12 Överprövning av upphandlingsmål m.m. should be passed into the acts of public procurement. The proposed law would imply that a party as support of its action is allowed to refer to new circumstances and evidences for the first

In neuroblastoma (NB) patients, minimal residual disease (MRD) can be detected by real-time quantitative PCR (qPCR) using NB-specific target genes, such as PHOX2B and TH. However, it is unknown whether the mRNA levels of these targets vary either during treatment or at relapse. If marker genes are not stably expressed, estimation of MRD levels in bone marrow (BM) or peripheral blood will be hamper

Background: Uveal melanoma is the most common primary intraocular malignancy in adults. Despite successful control of the primary tumor, metastatic disease will ultimately develop in approximately 50% of patients, with the liver being the most common site for metastases. The median survival for patients with liver metastases is between 6 and 12 months, and no treatment has in randomized trials eve

Background: In the present study the effect of a workplace-oriented intervention for persons on long-term sick leave for clinical burnout, aimed at facilitating return to work (RTW) by job-person match through patient-supervisor communication, was evaluated. We hypothesised that the intervention group would show a more successful RTW than a control group. Methods: In a prospective controlled study

Det är viktigt att undvika förseningar i ett rättssystem för att upprätthålla rättssäkerheten. Långa handläggningstider utsätter de berörda individerna för stress och osäkerhet, vilket kan riskera både effektiviteten och trovärdigheten av rättssystemet. Europakonventionen, som också är Svensk lag, innehåller bestämmelser om en rättvis rättegång inom skälig tid. Frågan är dock om Sverige lever up t

International Humanitarian Law (IHL) and International Human Rights Law (IHRL) are two different branches of International Public Law. While the IHL have a very long legal history, dating back many centuries, IHRL is of younger date having its big upswing in the decades after the Second World War. They have partially different scopes of application and different purposes, but they meet in their j

This report contains a fire safety evaluation of Le Cardinal, a restaurant and nightclub located in Helsingborg, Sweden. A normal Saturday evening Le Cardinal has about 400 guests in very various ages, from 20 to over 60 according to information from Johan Fredholm, safety responsible on Le Cardinal. The report only covers the early stages of the fire until untenable environments occur. It just co

The notion of "global warming" has become a major public-domain concept as an environmental threat to our future on earth. Independently of the accuracy of existing prediction of combustion emissions on the climate on earth, the concept of reducing combustion emissions has been an important political driving force in imposing more and more severe restrictions on harmful emissions from combustion.

Responses to isotonic quick releases of rabbit urinary bladder strips and rat portal veins activated by AC-stimulation and K+-high medium were studied. The AC stimulation was adjusted to give the same tension as th K+-contractures. Releases were performed at peak of the contractions (which was attained after 1.5-4.5 s AC-stimulation or 2-3 min in K+-high solution). The length response consisted of

Monapostrukturen ligger i Nampula provinsen i norra Moçambique, och utgör en del av Mocambique bältet. Strukturen är ca 35-40 km i diameter och har en mycket låg topografi. Trots detta syns den väl på satellitbilder och flygfotografier. Relationer mellan samt utbredning av de enskilda bergartsleden är inte helt klarlagd och frågor såsom transportriktning, litostratigrafisk uppdelning samt tektonisThe Monapo Structure is situated in the Nampula Subprovince in northern Moçambique, and makes up a part of the Moçambique Orogenic Belt. It is a 35 x 40 km subcircular structure, with a very flat topography, and it clearly shows up on aerial photos. The regional setting of the Monapo Structure is not yet clearly settled and many questions regarding transportation directions, lithostratigraphic gro

Managua has experienced two devastating earthquakes during the last century resulting in major human loss. The destruction in the earthquake of 1972 was particularly severe in defined areas of the city, including the former city centre, which is now unused terrain. This may have been because of amplification in those areas due to impedance contrasts and resonance effects in the surface layers. Th

BACKGROUND: We aimed to identify the target of deprescribing, i.e. the 24-hour SBP increase needed to achieve the greatest reduction of SBP drops.METHOD: Forty hypertensive patients (mean age 73.6 ± 9.3 years, 26 females) with reflex syncope and SBP drops on a screening ABPM were advised to withdraw or to reduce their therapy. The study objective was the reduction of SBP drops <90 mmHg and <100 mm

The primary aim of this study is to assess the significance of top management commitment in the context of Lean 4.0 implementation within the pharmaceutical manufacturing industry in Ghana. The study seeks to understand and evaluate the overall effectiveness and achievements associated with adopting Lean 4.0. Employing a positivist mindset, the research utilizes an explanatory quantitative researc

Förlust av biologisk mångfald är ett av de största hoten mot ekosystem och derasfunktioner. Nästan 500 arter i den marina miljön i Sverige anses idag vara hotade ellersårbara. En av dessa är Sveriges enda val, tumlaren (Phocoena phocoena), som lever längs hela Sveriges kust och rör sig över stora områden i sin jakt på fisk att äta. Mänsklig påverkan, framför allt genom oavsiktliga bifångster vid gThe harbour porpoise (Phocoena phocoena) is a small toothed whale with a mainly coastal distribution in the northern hemisphere. As a marine top predator, the species can act as an indicator for early warning signs of ecosystem changes. At the same time, harbour porpoises are globally threatened by human activities and in need of conservation. Successful protection of harbour porpoises requires un

This study aims to investigate and disentangle the impact of land use and climate variability on the Baltic Sea coastal zone from a millennial perspective. To assess the environmental status of the coastal zone we make use of siliceous microfossils (mainly diatoms), stable nitrogen and carbon isotopes, organic carbon accumulation rates, and lithological changes analyzed in a sediment core collecte

Previously, radiostereometric analysis following hip revision performed using impacted morsellised allograft bone and a cemented Exeter stem has shown continuous subsidence of the stem for up to five years. It is not known whether the subsidence continues thereafter. In our study, 17 of 25 consecutive osteo-arthritic patients with aseptically loose stems who underwent first-time revision using imp

The repair jobs that birds have to do to maintain high quality plumage take energy and time, so should be under intense selection. Recently, we have shown that secondary moult in the Eurasian Golden Plover Pluvialis apricaria is incomplete, irregular and asymmetric between wings, and argued that this reflected their ‘relaxed’ migratory habits. On the basis of this hypothesis, we predict that relat

Ceramic biomaterials are promising alternatives to bone autografts. However, limited bioactivity affects their performance. Therefore, bioactive molecules and cells are often added to enhance their performance. Exosomes have emerged as cell-secreted vesicles, delivering proteins, lipids, and nucleic acids in a paracrine/endocrine fashion. We studied two complementary aspects required for exosome a

Objectives: The aim of this study was to determine risk factors for development of acute myeloid leukemia/myelodysplastic syndromes (AML/MDS) in patients with multiple myeloma (MM). Methods: We identified all patients diagnosed with MM in Sweden from January 1st, 1958 to December 31, 2011. A total of 26 627 patients were diagnosed with MM with during the study period. Of these, 124 patients (0.5%)