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Motivation: Homology search finds similar segments between two biological sequences, such as DNA or protein sequences. The introduction of optimal spaced seeds in PatternHunter has increased both the sensitivity and the speed of homology search, and it has been adopted by many alignment programs such as BLAST. With the further improvement provided by multiple spaced seeds in PatternHunterll, Smith
The HIV-1 capsid protein, p24 antigen, is of considerable diagnostic interest because following HIV exposure it is detectable several days earlier than host-generated HIV antibodies (which are the target of almost all current tests used in the field) and can be used to design very sensitive assays without the need for PCR. Here, we present an ultrasensitive capacitive immunosensor that is capable
The national identity of the source culture often constitutes an important hermeneutic frame from which a translated text is understood. At the same time, literary texts themselves sometimes have a tendency to resist cultural narratives and stereotypical ideas of a certain nation. This article explores how such a resistance is made in the English translations of four Swedish novels from the 1930s.
Changing climatic conditions is a perpetual circumstance for mankind. In this study, we investigate local environmental and climatic changes near Kangerlussuaq, west Greenland. Our reconstruction is based on a lake sediment core and methods include chemical proxies and a palynological analysis. The investigated site is located 15 km from the Aasivissuit Inuit summer hunting ground, which has been
Lasten i ett fjärrvärmenät varierar mycket över dygnet på grund av variationer i väder, utomhustemperatur och användning av tappvarmvatten. För att driften av produktionsenheter ska bli jämnare används ofta värmeackumulering, de flesta fjärrvärmenät har tillgång till en ackumulatortank som kan fyllas med varmt vatten när lasten är låg för att sedan pumpa ut det i nätet vid hög last. I det här proj
Block copolymer lithography is a very promising candidate for nanoscale fabrication and is economically viable. It provides a high resolution, inexpensive, and straightforward approach to nano-size patterning. In this thesis, fundamental concepts and theories of block copolymer lithography are introduced. A well-controlled dynamic solvent vapor annealing chamber is built, and the best annealing co
Since the 1800’s the agriculture has changed and intensified significantly, going from small scale farming to large homogenous arable landscapes with fewer grazing animals, more fertilizers and pesticides. In Sweden, this pattern of intensification has been very distinct, especially in Scania, which today is dominated by plains. This has left substantial changes in the surrounding ecosystems, affe
Millimeter wave pulsed radar has found many applications, among them hand gesture sensing, which this work has as purpose. This application has already shown good potential, [1], and here in this work robustness aspects are taken into account. A classification task was defined, where distinction should be made between five different small hand gestures, recorded by 18 people in total. The classifi
Very sick patients who need specialized health services often require transport from their community to a regional facility that is appropriately resourced to provide definitive care for their condition. This is particularly important for people living in rural and remote areas but can be challenging due to long distances, mountainous terrain and inclement weather. The purpose of this research wa
Many construction companies have a construction service department but it is normally never the largest part of the company. Rather, the building services department has been seen as a fender to keep employees engaged when the economy’s been bad, with the result that no large investments have been put towards the service department. The logistics of the construction services business is different
The purpose of this study was to investigate how risk and vulnerability reducing measures are described, treated over time and what characterizes implemented measures in municipal risk and vulnerability assessments (RVA). In order to do that, risk and vulnerability reducing measures were categorized, by use of a template for document analysis developed for this study. The document analysis was per
Det har blivit allt mer tydligt att en förändring måste ske ifall de kriminella nätverken framfart ska kunna stoppas. Det dödliga vapenvåldet har ökat och det är av stor vikt att en förändring sker för att säkerställa att Sverige återigen hamnar på rätt kurs. I ett försök att åstadkomma detta valde den lagstiftande makten att implementera en kronvittnesbestämmelse i 29 kap 5a § BrB. Diskussionen kIt has become increasingly clear that there needs to be a change in order to stop the criminal networks in their pursuit of control. Lethal firearm violence has escalated and it is therefore crucial that a change occurs in order to make sure that Sweden returns to the right course. In an attempt to achieve this, the legislative authority in Sweden decided that it was time to implement a crown witn
The process in a mill is frequently monitored with the assistance of lists of measurement values and alarms from the process. Much time and concentration is sometimes needed to interpret these lists. If the process is described using a model the interpretation can be made automatically by a computer. This would unload the operator and permit the concentration of the operator to be focused on runni
High-throughput screening is one of the most extensively used methods for the identification of molecules of interest during early stages of drug development projects. It is however subject to many artifacts due to various mechanisms. Aggregation and redox cycling are examples of mechanisms of unspecific inhibition that make a large number of compounds appear as active in several high throughput s
This master’s thesis is about public libraries and how the work they do for children and youth in the summer holidays relates to public policy and reading research. Triangulation of methods is used with literature review, policy analysis, questionnaire survey and interviews. My primary theoretical framework is Carol Bacchi’s ’What’s the problem represented to be’ (WPR) approach, which is also us
I början av 2017 presenterade regeringarna i Finland, Norge och Sverige ett förslag till en Nordisk Samekonvention. I förslaget erkänns urfolk som folk med en rätt till självbestämmande. Förslaget kan sägas följa på den utveckling som skett internationellt inom området för mänskliga rättigheter. Urfolk har, sedan ungefär 40 år tillbaka, fått en allt starkare rättslig ställning. Baserat på denna ut
Authors: Jessica Bjurberg & Anna Engblom Title: Social Worker – the helping hand A qualitative study how active social workers experience their professional identity. Supervisor: Mikael Sandgren Assesor: Janicke Andersson The purpose of our study was to investigate how active social workers experience their professional identity. The method used for this investigation was semi-structured
The purpose of the report is to study whether it is economically profitable to start operate traffic on the Staffanstorp Line, the railway between Staffanstorp and Malmö. Also what resources and measures that are required will be studied. The activities that have been carried out are a literature study, a visit to the Staffanstorp Line and several calculations in form of cost estimates and costben
Computer security is still an often neglected field even though the IT industry is huge and still growing. Making sure that systems are secure is something that is very important but can take a lot of man hours. This thesis contains the research and documentation for an auditing tool created on behalf of a company that specialises in computer security, TrueSec. The audit tool uses the log files th
