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Malign hypertermikänslighet Malign hypertermikänslighet (malign hypertermi MH) är en ärftlig muskelåkomma, där narkos kan utlösa en potentiellt dödande ökning av ämnesomsättningen. Utredning sker huvudsakligen med hjälp av en öppen muskelbiopsi, i vissa fall med mutationsdiagnostik. MH enheten i Lund är ett nationellt centrum. Vår forskning har två huvudinriktningar Genetik: Vi har samarbete meMalign hypertermikänslighet Malignant hyperthermia is a hereditary muscle disease, which can be triggered by anesthesia. This may result in a potentially life-threatening increase in the metabolism. Evaluation of the patients occurs mainly through muscle biopsi, sometimes with mutation diagnostica. The MH unit i Lund is a national centra. The reasech can be divided in 2 parts: Genetic: The aim o

OBJECTIVE: The aim of this study was to increase our understanding of the multifaceted phenomenon of home and health, by exploring processes underlying these dynamics when living at home in very old age. METHOD: A qualitative meta-synthesis was used on four complementary qualitative studies, based on data from the Swedish ENABLE-AGE In-depth Study, focusing on very old, single-living people's expe

Hydrofluorocarbons (HFCs) are used in a range of industrial applications and have largely replaced previously used gases (CFCs and HCFCs). HFCs are not ozone-depleting but have large global warming potentials and are, therefore, reported to the United Nations Framework Convention on Climate Change (UNFCCC). Here, we use four independent inverse models to estimate European emissions of the two HFCs

Artificial Intelligence in Cardiothoracic Science was funded 2006. Traditionally, medical decisions are based on the combined strength of clinical facts and the experience of the clinician. A growing understanding of the molecular, genetic and biochemical basis of diseases have greatly increased the degree of complexity in medical decision-making. To identify risk factors in medical registers, a n

The invention of computers revolutionized the way of doing science and in particular the field of mathematics. Computers were faster than any human mind in doing calculations and they did not make mistakes opening a wide range of possibilities that earlier where in practice uncomputable. Scientists observe the behavior of nature and find mathematical equations that model the different phenomena. IThe efficient simulation of thermal interaction between fluids and structures is crucial in the design of many industrial products, e.g. turbine blades or rocket nozzles. The main goal of this work is to present a high order time adaptive multirate parallel partitioned coupled method for the efficient numerical solution of two parabolic problems with strong jumps in the material coefficients that

An ambient wall with a window were studied with both theoretical analyses and measurements performedunder conditions with natural climate. The method used wes to estimate the heat flow through wall and windowfrom measured temperatures and solar radiation. The longwave radiation was calculated from surface temperatures. The convective heat transfer was caculated as the difference between the heat f

Urban Gullberg är forskargruppschef för forskargruppenUrban Gullberg is Research Group Leader for this research group

Minimalinvasiv hjärtkirurgi definieras som hjärtkirurgiska operationstekniker där man avstår från en full median sternotomin (längsgående delning av hela bröstbenet). Hjärtoperationen sker då istället med alternativa exponeringstekniker under det att man använder konventionell hjärt-lungmaskin. Beroende på diagnos utförs antingen operationen med video-assisterad, eller robot-assisterad, endoskopi Minimally invasive cardiac surgery is defined a cardiac surgery with heart-lung machine, but without full median sternotomy. Depending on the underlying disease the surgical procedures can be performed through a 4-6 cm mini-thoracotomy on the right side with either video-assisted or robotic-asssited endoscopy or through a partial split of the sternum. We believe that minimally invasive facilitate

Forskargruppen "Barninfektioner och global barn- och ungdomshälsa" främjar forskning och utbildning. Det primära forskningsområdet är pediatrik och mer specifika inom området barninfektioner, Kawasakis sjukdom, global barn och -ungdomshälsa samt migration. Forskargruppen samarbetar med andra forskargrupper både nationellt och internationellt. Forskargruppen är involverad i utbildningen av läkarsPediatric infectious diseases and global child health is a research group promoting high quality research and education. The primary area of research is Pediatrics and more specific in the field of infectious diseases, Kawasaki disease, global child health and migration. The research group collaborates with research teams both nationally and internationally as well as being involved in the educa

Varje år tar cirka 1500 personer sitt liv i Sverige. Det är en minskning sedan 1980-talet men de senaste femton åren har minskningen stannat av. Enheten för klinisk suicidforskning arbetar med olika områden inom suicidforskning med det övergripande syftet att bättre förstå hur suicid kan förebyggas. •Område A: Psykopatologi och riskfaktorer för patienter med risk för framtida suicid. Vi undersökeSuicide research is of importance to find new strategies to prevent suicide. Each year approximately 800 000 people in the world, and 1500 people in Sweden commit suicide. The suicide rate has not decreased over the last 15 years. The Unit for Clinical Suicide Research cover different areas within this field. • Area A: Psychopathology and risk factors. Our group investigates how psychopathology

Concerns regarding environmental issues such as greenhouse gas emissions and climate change have led to a shift within the research community and chemical and energy industry sectors for finding sustainable routes for producing fuels and chemicals from renewable resources, thereby minimizing our dependence on petroleum. The C3-chemical 3-hydroxypropionic acid has been identifed as a top candidate

We challenge the question of how environmental (diet, physical activity, alcohol) factors modify genetic associations put forward by us and others, in recent genome wide association studies (GWAS) of lipoprotein traits, cardiovascular disease (CVD) and obesity and aim to utilize this information in intervention studies and in development of prediction models. We work to further improve genetic C

Our main focus is understanding peripheral pathology in HD and investigate its importance for disease pathogenesis and biomarkers. Our work is based on the hypothesis that insights into peripheral pathology in HD will improve knowledge of key pathogenic mechanisms, possibly providing new biomarkers and novel therapeutic targets.

Preeklampsi är ett allvarligt graviditetsrelaterat tillstånd som årligen drabbar 10 miljoner kvinnor världen över. Etiologin är ännu okänd och diagnosen ställs baserad på moderns kliniska symptom: högt blodtryck och någon organpåverkan som debuterar efter 20 veckors graviditet. För närvarande är förlossning den enda ”boten”. Preeklampsi medför en ökad långsiktig risk för utveckling av hjärt-kärlsjPreeclampsia is a severe pregnancy-related condition that annually affects 10M women worldwide. The etiology is largely unknown and diagnosis is currently based on maternal clinical symptoms: high blood pressure and organ damage manifesting after 20 weeks of gestation. Delivery is currently the only cure. Increased long-term risk for cardiovascular diseases and stroke after preeclampsia point to i

Vår forskning fokuserar på personer med allvarlig och långvarig psykisk sjukdom och deras livssituation i samhället. De omfattande omstruktureringarna av det psykiatriska vård- och stödsystemet har inneburit långtgående krav på en utveckling av nya kunskapsbaserade vård- och stödinsatser. Detta för att främja hälsa och ett meningsfullt liv i samhället för den här gruppen och deras anhöriga. Många Our research focuses on individuals with severe and long-lasting mental illness and their situation in society. The extensive restructuring of the mental health and support systems towards community-based service systems brings forth far-reaching requirements for developing new knowledge-based health and support interventions. Such efforts are needed to favour and support health and a meaningful l