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Chemical cross-linking was used to analyze the binding sites for the agonist bradykinin (BK) and the antagonists NPC17731 and HOE140 on the bovine B2 bradykinin receptor. [3H]BK and [3H]NPC17731 bound with high affinity to the same B2 receptor in bovine myometrial membranes as determined by the total number of specific binding sites and pharmacological specificity of the binding of these two radio

Purpose: This study aims to focus on the surface curvature, jet to target spacing and jet Reynolds number effects on the heat transfer and fluid flow characteristics of a slot jet impinging on a confined concave target surface at constant jet to target spacing. Design/methodology/approach: Numerical simulations are used in this research. Jet to target spacing, H/B is varying from 1.0 to 2.2, B is

This article examines how the Muslim veil and call to prayer are constructed as social problems in motions to the Swedish parliament between 2010 and 2024. Analyzing 120 political proposals, the study reveals how these religious practices are portrayed as problematic by constructing them as threatening to Swedish values, particularly gender equality and secularism. Using Carol Lee Bacchi’s “What’s

Human-induced climate change continues to have a disproportionate negative impact on people and the planet. The human dimension must be included to make a change to reduce the environmental challenges we are facing. As mobile digital technologies have developed, the use of gamification has emerged as a way to promote pro-environmental behavior. As the field is relatively new, the research on the t

With the growing integration of renewable energy sources into the power grid, new challenges for system stability have emerged. To address this, the European Union has introduced a regulation called Requirements for Generators (RfG). This regulation sets specific performance standards, one of which is a minimum critical clearing time related to faults. Some production facilities with low inertial

In this study we compared plasma contents of long-chain polyunsaturated fatty acids (LC-PUFAs) and trans fatty acids in triglycerides (TG), phospholipids (PL) and cholesterolesters (CE) in young children fed milk diets containing different amounts of linoleic (LA) and alpha-linolenic acid (ALA). Because the diets differed in vitamin A and E content, plasma concentrations of vitamin A and E were al

The R2 protein subunit of class I ribonucleotide reductase (RNR) belongs to a structurally related family of oxygen bridged diiron proteins. In wild-type R2 of Escherichia coli, reductive cleavage of molecular oxygen by the diferrous iron center generates a radical on a nearby tyrosine residue (Tyr122), which is essential for the enzymatic activity of RNR, converting ribonucleotides into deoxyribo

The five Nordic species of the genus Urytalpa Edwards (Diptera: Keroplatidae) are revised, of which one species, Urytalpa galdes Hedmark & Kjaerandsen, sp. n., is described as new to science based on males collected in northern Sweden. We find that the original type species assignment for Urytalpa (Platyura ochracea Meigen, 1818) is based on a misidentification, and in order to stabilize the n

Presents a new view of the standard of living development in Sweden during the agricultural revolution, using evidence on the ability to overcome short-term economic stress. The results corroborate previous findings, based on a variety of indicators, that standard of living in Sweden increased for most people after the mid-nineteenth century, but also support a more negative view of the immediate

BackgroundEarly life factors influence the number of nephrons a person starts life with and a consequence of that is believed to be premature kidney ageing. Thus, we aimed to identify early life factors associated with cystatin C and creatinine-based estimated glomerular filtration (eGFR) rate equations and urine -albumin-to-creatinine ratio after a follow-up of 46–67 years.MethodsThe study includ

This study is a continuation of our research on understanding the possible chemical routes to the evolution of life on earth based on the “Selective Energy Transfer” (SET) theory. This theory identifies the specific vibrational mode of the catalyst that is in energy-resonance with a suitable vibrational mode of the reactant. In this way, energy is transferred from catalyst to reactant up to the en

De första levande organismerna uppstod på jorden när den funnits i 1,5 miljarder år. Under de följande tre miljarder åren bildades livet på jorden, och existerade i harmoni, med gravitation, kosmisk-strålning, elektriska och magnetiska fält och dess cyklisk-hemlighetsfulla variationer medan exponeringen från den naturlga mikrovågstrålningen var endast i storleksordningen 210-15 W/kg. Det var i deOur team of the clinical researchers in Lund, Sweden, found that electromagnetic radiation, such as those used in mobile communications, even at shallow power values, cause users’ blood albumin to leak through the blood-brain barrier “BBB” into the brain tissue. The BBB is supposed to protect the brain against unwanted and toxic molecules potentially present in the blood, to transfer to the brain

Manufacturing of biopharmaceuticals is a costly and time consuming process due to its inherent complexity and variability. The downstream process is the most expensive part and it involves multiple non-trivial steps. Continuous integrated manufacturing is a new concept that is encouraged by authorities. The advantages include uninterrupted operation, automation, consistent product quality, lower rManufacturing of biopharmaceuticals is a costly and time consuming process due to its inherent complexity and variability. The downstream process is the most expensive part and it involves multiple non-trivial steps. Continuous integrated manufacturing is a new concept that is encouraged by authorities. The advantages include uninterrupted operation, automation, consistent product quality, lower r

Gambling disorder is associated with severe financial, social, and psychological consequences, but treatment-seeking rates have been described to be low. Apart from formal treatment, motivational interventions in nontreatment-seeking high-risk gamblers have been shown to be promising. However, little is known about the effectiveness and acceptability of such motivational interventions carried out