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In a previous study we presented data indicating that the expanded population of CD4(-)CD8(-) (DN) alphabeta T cells in TCRalpha-chain-transgenic mice was partially if not entirely derived from gammadelta T cell lineage cells. The development of both gammadelta T cells and DN alphabeta T cells is poorly understood; therefore, we thought it would be important to identify the immediate precursors of

Immunoglobulin G (IgG) glycosylation modulates antibody activity and represents a major source of heterogeneity within antibody preparations. Depending on their glycosylation pattern, individual IgG glycovariants present in recombinant antibody preparations may trigger effects ranging from enhanced pro-inflammatory activity to increased anti-inflammatory activity. In contrast, reduction of IgG gly

Protein kinase C (PKC) plays a prominent role in immune signaling, and the paradigms for isoform selective signaling are beginning to be elucidated. Real-time microscopy was combined with molecular and biochemical approaches to demonstrate a role for PKC-epsilon in Fcgamma receptor (FcgammaR)-dependent phagocytosis. RAW 264.7 macrophages were transfected with GFP-conjugated PKC isoforms, and GFP m

Measurements are presented of inclusive charm and beauty cross sections in e(+)p collisions at HERA for values of photon virtuality 12 <= Q(2) = 60 GeV2 and of the Bjorken scaling variable 0.0002 <= x <= 0.005. The fractions of events containing charm and beauty quarks are determined using a method based on the impact parameter, in the transverse plane, of tracks to the primary vertex, as measured

Current hemophilia B treatment guidelines recommend routine prophylaxis with factor IX (FIX) replacement products, tailored to maintain plasma activity at levels that will prevent bleeds. However, plasma FIX activity may not be the primary determinant or best indicator of hemostatic efficacy due to its extravascular distribution. FIX replacement therapy has evolved to include extended half-life (E

https://www.hr-webben.lu.se/sites/hr-webben.lu.se/files/2025-04/Support%20material%20for%20managers%20-%20Handling%20and%20investigating%20professional%20misconduct.pdf - 2025-11-20

Postadress Lunds universitet, Institutionen för arkitektur och byggd miljö, Box 118, 221 00 LUND Telefon 046-222 00 00 1(2) Webbadress www.lth.se TT/2025-05-14 Department o f Arch i tecture and Bui l t Env i ronment Contract concerning the internship within the course AAHF40: Architectural Education at Workplace, 30 credits, at the School of Architecture, Lund University §1 Parties 1 The Departmen

https://www.abm.lth.se/fileadmin/arkitektur/Arkitektur_och_byggd_miljoe/AAHF40_contract_250422.pdf - 2025-11-03

This article analyses and discusses standardisation in human service organisations and its implications for professionals and for professionalism in social work. The theoretical framework derives from neo-institutional theory and theories regarding professionalism. By highlighting the role of professionals within a field influenced by organisational demands and market endeavour, this article contr

Honor-related violence and oppression is a widely discussed phenomenon that occurs in cultures and societies all over the world. The aim of this study was to examine the complexities of applying legislation and official guidelines in addressing honor-related violence. Drawing upon the theoretical frameworks of street-level bureaucracy and legal pluralism, this study explored how professionals in s