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Probiotics are increasingly gaining popularity in vast food applications due to their recognized health benefits to the host. However, their passage through the gastrointestinal (GI) tract is not smooth and a significant number of physiological barriers (e.g. low pH, bile salts, enzymes, peristaltic movements, etc.) may considerably affect their viability. The entrapment of probiotics in protectiv
The efficacy of serotonin reuptake inhibitors in depression and anxiety disorders suggests the gene coding for the serotonin transporter (5-HTT), SLC6A4, as a candidate of importance for these conditions. Positive findings regarding associations between polymorphisms in SLC6A4 have been reported, indicating that these polymorphisms may influence anxiety-related personality traits, as well as the r
Assessments of long-term changes of air quality and global radiative forcing at a large scale heavily rely on satellite aerosol optical depth (AOD) datasets, particularly their temporal binning products. Although some attempts focusing on the validation of long-term satellite AOD have been conducted, there is still a lack of comprehensive quantification and understanding of the representativeness
The structure and dynamics of proteins in solution are closely related to their activity and, ultimately, to their performance in products and technologies, for example, drug formulations and enzymatic catalysis. With this in mind, the study of the fundamental behavior of proteins in deep eutectic solvents not only provides insight into a novel alternative to aqueous and molecular organic solvents
The Swedish Historical Regional Accounts 1571–2022, released in 2014 and 2018, presents a database with regional GDPs for 24 countries. Please cite this database as: Enflo, K., Henning, M. & Schön, L. (2014) ”Swedish Regional GDP 1855–2000: Estimations and General Trends in the Swedish Regional System”. In Christopher Hanes, Susan Wolcott (ed.) Research in Economic History, vol 30, Emerald Group P
The mechanical properties of structural timber—particularly in terms of stiffness and strength—are subject to high variability, which also affects the properties of timber products made from structural timber, e.g., glued laminated timber (GLT). In this paper, the influence of the longitudinal stiffness variability of wooden lamellas on the effective stiffness of GLT is investigated. In a first st
In this paper we provide necessary and sufficient conditions for strongly group graded rings to be simple. For a strongly group graded ring R the grading group G acts, in a natural way, as automorphisms of the commutant of the neutral component subring R_e in R and of the center of R_e. We show that if R is a strongly G-graded ring where R_e is maximal commutative in R, then R is a simple ring if
Background: Foods with a low glycemic index are increasingly being acknowledged as beneficial in relation to the insulin resistance syndrome. Certain organic acids can lower the glycemic index of bread products. However, the possible effect of acids in fermented milk products on the glycemic index and on insulinemic characteristics has not been addressed. The metabolic effects of fermented milk or
Scientific abstract: As the increasing attentions drawn to the environment and climate change issue, the profound impact on the earth system made known to nearly every corner of the world. A great variety of global protocols and conventions has been established aiming to reduce global environmental risks and maintain a healthy earth system. In order to monitor, supervise these protocols and conven
S100A4 and S100A9 proteins have been described as playing roles in the control of tumor growth and metastasis. We show here that a chemical probe, oxyclozanide (OX), selected for inhibiting the interaction between S100A9 and the receptor for advanced glycation end-products (RAGE) interacts with both S100A9 and S100A4. Furthermore, we show that S100A9 and S100A4 interact with RAGE and TLR4; interac
Discrete Time Markov Chains (DTMCs) and Con- tinuous Time Markov Chains (CTMCs) are often used to model various types of phenomena, such as, for example, the behavior of software products. In that case, Markov chains are widely used to describe possible time-varying behavior of “self-adaptive” software systems, where the transition from one state to another represents alternative choices at the so
Therapeutic antibodies are the fastest growing class of drugs but suffer from a crowded target-space where many antibodies, against a few targets, are developed in parallel. The aim of this thesis is to find methods to enable discovery of novel antibody-target combinations and thereby increase the target-space. A strategy to achieve this is to use phage display antibody libraries and selection on
In 2017, the new SMOS-IC retrieval product of soil moisture (SM) and L-band Vegetation Optical depth (L-VOD) was developed. This product relies on a two-parameter inversion of the L-MEB model (L-band Microwave Emission of the Biosphere) which requires little ancillary information and was found to be accurate, making it very well-suited for application in agriculture, hydrology, climate and vegetat
Precipitation can be quantified using a rain gauge network, or a remotely sensed precipitation product. Ultimately, the choice of dataset depends on the particular application, the catchment size, climate and the time period of study. In a region with a long record and a dense rain gauge network, the elevation-modified ground-based precipitation product, PRISM, has been found to work well. However
This paper investigates the heterogeneity of the sources of external knowledge and their differentiated effects on process and product innovations respectively. The results of the empirical investigations show that the upstream vertical sources of external knowledge from suppliers exert a strong and positive role on the introduction of process innovations, whereas horizontal and downstream vertica
Graphical user interface (GUI) development is generally complicated, time-consuming, and requires programming knowledge. In the context of the internet of things, this work focuses on producing an efficient development approach that also supports non-experts. We introduce a novel "inverted" development approach that does not require program code to be written - a step towards supporting end-user d
Signal apparition is a method for encoding sources in simultaneous multisource seismic acquisition and decoding the multisource response of the earth into its single-source responses. For M sources, encoding is performed by applying periodic sequences of period M to each of the sources along source lines. Decoding is achieved in the wavenumber domain for each frequency by solving an M × M linear s
