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Possible heterogeneity of initial pancreatic islet beta‐cell autoimmunity heralding type 1 diabetes Review-Symposium doi: 10.1111/joim.13648 Possible heterogeneity of initial pancreatic islet beta-cell autoimmunity heralding type 1 diabetes Åke Lernmark1 , Beena Akolkar2, William Hagopian3, Jeffrey Krischer4, Richard McIndoe5, Marian Rewers6, Jorma Toppari7, Kendra Vehik4, Anette-G. Ziegler8 & The
https://www.teddy.lu.se/sites/teddy.lu.se/files/2023-11/151_2.pdf - 2026-05-29
1 Årsrapport 2024-2025 TEDDY HAR GÅTT I MÅL ATT SAMLA IN PROVER OCH DATA TEDDY - Omgivningsfaktorer för utveckling av autoimmun (typ 1) diabetes, celiaki och sköldkörtelinflammation hos barn 2 Lina Fransson, Ida Jönsson, Malin Goldman Tsubarah och Åke Lernmark Institutionen för kliniska vetenskaper Malmö, Lunds Universitet, Skånes Universitetssjukhus, Malmö Innehållsförteckning 1. TEDDY-studien –
https://www.teddy.lu.se/sites/teddy.lu.se/files/2026-01/TEDDY%20A%CC%8Arsrapport%202024-2025%20v.3%20(sist).pdf - 2026-05-29
1 Årsrapport 2024-2025 TEDDY HAR GÅTT I MÅL ATT SAMLA IN PROVER OCH DATA TEDDY - Omgivningsfaktorer för utveckling av autoimmun (typ 1) diabetes, celiaki och sköldkörtelinflammation hos barn 2 Lina Fransson, Ida Jönsson, Malin Goldman Tsubarah och Åke Lernmark Institutionen för kliniska vetenskaper Malmö, Lunds Universitet, Skånes Universitetssjukhus, Malmö Innehållsförteckning 1. TEDDY-studien –
https://www.teddy.lu.se/sites/teddy.lu.se/files/2026-01/TEDDY%20A%CC%8Arsrapport%202024-2025%20v.3.pdf - 2026-05-29
Arctic-breeding birds are of particular conservation concern since their habitats are subject to severe changes and shifts upwards in both altitude and latitude due to global warming. Detailed knowledge on habitat characteristics of those species is required to understand how specialized Arctic-breeding species deal with changing habitat conditions. Therefore, sufficient data and methods to assess
Sustainably produced renewable biomass has the potential to replace fossil-based feedstocks, for generation of biobased fuels and chemicals of industrial interest, in biorefineries. In this context, seaweeds contain a large fraction of carbohydrates that are a promising source for enzymatic and/or microbial biorefinery conversions. The thermoanaerobe Thermoanaerobacterium AK17 is a versatile ferme
How to maintain and enhance cognitive functions for both aged and young populations is a highly interesting subject. But candidate memory-enhancing reagents are tested almost exclusively on lesioned or aged animals. Also, there is insufficient information on the type of memory these reagents can improve. Working memory, located in the prefrontal cortex, manages short-term sensory information, but,
Despite the desire to utilize proactive safety metrics, research results indicate imbalances can arise between economic performance metrics and safety metrics. Imbalances can arise, first, because there are fewer proactive metrics available relative to the data an organization can compile to build reactive metrics. Second, there are a number of factors that lead organizations to discount proactive
We provide evidence of a positive effect of major infrastructure development on international trade, using the opening of the fixed link between Denmark and Sweden in 2000 (The Oresund Bridge) as a quasi-natural experiment. Our Synthetic Control Method (SCM) constructs a counterfactual Danish-Swedish trade relationship, which represents bilateral trade in the absence of the bridge. Evaluating actu
We used eddy-covariance (EC) measurements of net ecosystem exchange (NEE) above canopy to assess the effects of thinning on CO2 fluxes at the ICOS Sweden site Norunda in central Sweden. This forest site consists of mixed pine and spruce stands approx. 100 years old. The thinning during late autumn 2008, performed in a semicircle from the mast extending 200m outwards harvested about 25% of the voluWe used eddy-covariance (EC) measurements of net ecosystem exchange (NEE) above canopy to assess the effects of thinning on CO2 fluxes at the ICOS Sweden site Norunda in central Sweden. This forest site consists of mixed pine and spruce stands approx. 100 years old. The thinning during late autumn 2008, performed in a semi-circle from the mast extending 200 m outwards harvested about 25% of the vo
The setting (distance between mantle and concave ring) of the Hydrocone cone crusher is altered, even with the crusher operating at full load, by lifting or lowering the mantle by means of a hydraulic piston (Hydroset). Modern developments in the field of electronics and microcomputers have made it possible to design a small, reliable and very sophisticated system for automatic regulation of the s
Background: To target specific neuronal populations by gene transfer is challenging. A complicating fact is that populations of neurons may have opposing roles despite being found adjacent to each other. One example is the medium spiny neurons of the striatum. These cells have different projection patterns, a trait used in this study to specifically target one population. New Method: Here we prese
There has been a strong quest for mapping and assessing ecosystem services (ES) to support governance. Yet, the institutional landscape that governs ES provision across multiple contexts has received less attention. We fill this research gap by developing and operationalising a framework for the analysis of policy documents that address European forest ES provision. By coding and analysing referen
We consider the pebble game on DAGs with bounded fan-in introduced in [Paterson and Hewitt '70] and the reversible version of this game in [Bennett '89], and study the question of how hard it is to decide exactly or approximately the number of pebbles needed for a given DAG in these games. We prove that the problem of deciding whether s pebbles suffice to reversibly pebble a DAG G is PSPACE-comple
The beneficial effects of protons are primarily based on reduction of low to intermediate radiation dose bath to normal tissue surrounding the radiotherapy target volume. Despite promise for reduced long-term toxicity, the percentage of cancer patients treated with proton therapy remains low. This is probably caused by technical improvements in planning and delivery of photon therapy, and by high
This article investigates whether regime-based asset allocation can effectively respond to changes in financial regimes at the portfolio level in an effort to provide better long-term results when compared to a static 60/40 benchmark. The potential benefit from taking large positions in a few assets at a time comes at the cost of reduced diversification. The authors analyze this trade-off in a mul
Katalys är ryggraden i många processer i vardagen. Även människokroppen styrs huvudsakligen av katalysatorer. Detta viktiga koncept tillåter oss att på ett miljövänligt sätt konvertera råmaterial som råolja och naturgas till värdefulla och oersättliga produkter, till exempel motorbränslen, läkemedel och agrokemikalier. En katalysprocess drivs av en katalysator, vilket således är en substans som, uNew classes of N-heterocyclic carbene-palladium(II) complexes containing either a vinyl group in different positions or an anthracene tag in the backbone of the N-heterocycle were synthesized and fully characterized. The vinyl based complexes were copolymerized with divinylbenzene to fabricate robust polymer-supported NHC-Pd(II) systems, while the anthracene based complexes were π-stacked onto the
Changes in farming practices over the past century have had negative influence on farmland biodiversity. Organic farming excludes most agrochemicals, such as inorganic fertilisers and synthetic pesticides, and can be an alternative to conventional farming. A recent meta-analysis indicates that there is on average 30% higher species richness on organically managed farmland compared to conventionall
Background: Optimal infusion rate of colloids in patients with suspected hypovolemia is unknown, and the primary objective of the present study was to test if plasma volume expansion by 5% albumin is greater if fluid is administered slowly rather than rapidly. Methods: Patients with signs of hypoperfusion after major abdominal surgery were randomized to intravenous infusion of 5% albumin at a dose
Asthma is a chronic inflammatory disease of the airways, affecting and disablingapproximately 300 million people worldwide. The inflammatory profile ischaracterized by infiltration of eosinophils, which are a rich source of factors thatare implicated in tissue remodeling. The chronic inflammatory response and theremodeled phenotype create a hospitable environment for secondary bacterialinfections.
