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As the world population is pushing toward 8 billion, cardiovascular diseases (CVD) remain the leading cause of death worldwide, representing 30% of all global deaths. A large body of work has recognized that smooth muscle cells (SMCs) surrounding the blood vessels play a prominent role in the development and progression of cardiovascular diseases. SMCs are highly specialized cells with the main fu

Lewis' concept of admissibility was introduced as an integral part of his famous Principal Principle; the principle that initial rational/reasonable belief should conform to objective chance unless there is evidence to the contrary. At that time Lewis offered only the rough and ready characterisation that evidence not to the contrary of such dependence is admissible. This, together with some suffi

Background This study aimed to describe the incidence rate, patient characteristics, treatments, and outcomes of adults hospitalized with Mycoplasma pneumoniae pneumonia. Methods This retrospective cohort study included adults diagnosed with M pneumoniae pneumonia and admitted to emergency care hospitals in Stockholm County, Sweden, from 2013 to 2017. Patients were identified through positive M pn

Atrial fibrillation (AF) is the most common arrhythmia in the world, leading to a significant burden to patients and the healthcare system. It is characterised by rapid and irregular atrial contractions stemming from disorganised electrical activity in the atria. The atrioventricular (AV) node regulates heart rate during AF by filtering electrical impulses from the atria.However, for persistent AF

Background: Motion sickness (MS) is a common complaint during most modes of travel. Several medications can be used to treat MS but are often accompanied by side-effects. Objective: To assess whether performing the Valsalva manoeuvre can influence the subjective feeling of MS in healthy individuals. Methods: We included 16 healthy participants (4 female) that underwent two sessions of MS induction

The MAKEDEP model is used to reconstruct the time-series input files of deposition, forest growth, uptake and litterfall needed to run the dynamic biogeochemical model SAFE. The amounts and timing of N made available for tree growth is what determines most of the model output. In this paper, the sensitivity Of MAKEDEP to various amounts and timing of N availability, including increased supplies of

Emissions from biomass burning are highly variable and depend on combustion conditions as well as fuel properties. Simultaneous emissions from pyrolysis, smouldering, and combustion of the biomass material(s) burning leads to uncertainties in how these processes contribute to emissions of individual or groups of compounds as well as to total particle emissions. These uncertainties are difficult to

Vegetable oils and fats are major energy sources but also play an essential part in the physical and chemical properties of food products. The current change in the climate is affecting harvest yields, leading to a shortage and increased prices of raw materials that are difficult to replace. In addition, there is an increasing demand for new products with positive health effects.Triacylglycerols (

Background strain is known to influence the way a genetic manipulation affects mouse phenotypes. Despite data that demonstrate variations in the primary phenotype of basic inbred strains of mice, there is limited data available about specific metabolic fluxes in vivo that may be responsible for the differences in strain phenotypes. In this study, a simple stable isotope tracer/NMR spectroscopic pr

We provide evidence that the human papillomavirus (HPV) E2 protein regulates HPV late gene expression. High levels of E2 caused a read-through at the early polyadenylation signal pAE into the late region of the HPV genome, thereby inducing expression of L1 and L2 mRNAs. This is a conserved property of E2 of both mucosal and cutaneous HPV types. Induction could be reversed by high levels of HPV-16

Aims/hypothesis Insulin autoantibodies (IAA) are important in type I diabetes risk assessment. However, their determination varies more between laboratories than other diabetes autoantibodies. The Diabetes Antibody Standardization Program (DASP) aims to improve and standardise measurement of autoantibodies associated with type I diabetes. We report the results of measurement of IAA from DASP works

Genomes of prokaryotes differ significantly in size and DNA composition. Escherichia coli is considered a model organism to analyze the processes involved in bacterial genome evolution, as the species comprises numerous pathogenic and commensal variants. Pathogenic and nonpathogenic E. coli strains differ in the presence and absence of additional DNA elements contributing to specific virulence tra

Many mammals have specialized nose-tips with glabrous and often wet skin, called rhinaria. The function of the rhinarium is unknown in most species. Rhinaria differ not only in shape and skin structure, but also in skin temperature. They are considerably colder in carnivorans than in herbivorous artio- and perissodactyls. Domestic dogs are carnivorans and their noses often feel cold, such that the

In this study, the presence of anisakid nematodes in the European eels (Anguilla anguilla L.) was investigated. A total of 30 specimens of eels were caught by local fishermen from the Buyuk Menderes River, Turkey. Nematoda species of Raphidascaris acus was found from eels. This is the first record of R. acus from A. anguilla from Turkish waters. The ribosomal DNA (rDNA) internal transcribed spacer

Apart from providing some new experimental data the paper reviews previous investigations concerning fluctuating lift acting on a stationary circular cylinder in cross-flow. In particular, effects of Reynolds number in the nominal case of an infinitely long and nonconfined cylinder in a smooth oncoming flow are discussed. The Reynolds number range covered is from about Re = 47 to 2 x 10(5), i.e.,

A humus soil with a pH(H2O) of 4.9 was limed to a pH of 7.5 and was incubated together with samples from unlimed and field limed (pH 6.1) soils at 5, 20 and 30degreesC for up to 80 days. The changes in the phospholipid fatty acid (PLFA) pattern were most rapid for the bacterial community of the soil incubated at 30degreesC, while no changes were found in the soil incubated at 5degreesC. The respon

BACKGROUND: Previous analyses concerning health components of European Union (EU)-funded research have shown low project participation levels of the 12 newest member states (EU-12). Additionally, there has been a lack of subject-area analysis. In the Health Research for Europe project, we screened all projects of the EU's Framework Programmes for research FP5 and FP6 (1998-2006) to identify health

Ensamrätten till ett varumärke är en dynamisk rätt, där skyddsomfånget förändras över tid. Skyddsomfånget avgörs utefter graden av särskiljningsförmåga, vilket innebär ett varumärkes förmåga att särskilja varumärkesinnehavarens varor eller tjänster från andra näringsidkares varor eller tjänster. Vid varumärkesregistrering är särskiljningsförmåga ett absolut krav. Är fallet så att ett varumärke helA trademark right is a dynamic right, where the scope of protection alters over time. The scope of protection is determined according to the degree of distinctiveness, which means the trademark’s ability to distinguishing the goods and services of one trader from the goods and services of another. A trademark must be capable of distinguishing to be registered. If a trademark has completely lost it

A study of the decays B s 0 → μ + μ − and B 0 → μ + μ − has been performed using 26.3 fb −1 of 13 TeV LHC proton-proton collision data collected with the ATLAS detector in 2015 and 2016. Since the detector resolution in μ + μ − invariant mass is comparable to the B s 0 -B 0 mass difference, a single fit determines the signal yields for both decay modes. This results in a measurement of the branchi