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Agricultural intensification has been vital for meeting global food demand but has caused environmental degradation. This has disrupted the ability of soil to provide vital ecosystem services. Organic farming is often thought to conserve and utilise soil ecosystem services, and thus be a more sustainable method of food production than conventional farming. However, evidence for this is equivocal,

Abstract in Norwegian Hovudlina i forskinga på lesing og skriving byggjer på tanken om at talt språk på alle vesentlege punkt er primært i høve til skrive språk. Omgrepsapparatet for studiet av språk og lese- og skrivedugleik er også bygd kring denne tanken. Dette er problematisk frå eit vitskapsteoretisk standpunkt sidan tanken om det talte språket sin dominans ikkje er tilstrekkeleg empirisk undMainstream research on reading and writing is based on the assumption, common in modern linguistics, that spoken language is primary to written language in most important respects. Unfortunately, the conceptual framework for the study of language and 'literacy' (encompassing both reading and writing skills) is built around this assumption. This is problematic with regard to the philosophy of scien

Popular Abstract in Swedish Denna avhandling baserar sig på de erfarenheter av Internet som ett antal människor med betydande kroppsliga funktionsnedsättningar gjort. Personerna i studierna är erfarna och duktiga dator- och Internetanvändare och har få eller inga funktionshinder i dator och online världen, men däremot stora funktionshinder i den fysiska världen. Deras functioning, förmåga attThis thesis is based on the Internet experiences of people with significant mobility/physical impairments who are proficient and experienced computer users in their computer world but have limitations in mobility that severely restrict their functioning in the physical world. The Internet functioning of this group is analysed by means of the factors attitude, control and enabling, with the m

A selection of searches by the ATLAS experiment at the LHC for the electroweak production of SUSY particles are used to study their impact on the constraints on dark matter candidates. The searches use 20 fb−1 of proton-proton collision data at s=8 TeV. A likelihood-driven scan of a five-dimensional effective model focusing on the gaugino-higgsino and Higgs sector of the phenomenological minimal s

Context: Women with Turner syndrome (TS) have high risk of cardiovascular complications and hypertensive disorders. Few studies have analyzed obstetric outcome in women with TS. Objective: This study compared obstetric outcome in women with TS karyotype with women in the general population. Design: The Swedish Genetic Turner Register was cross-linked with the Swedish Medical Birth Register between

BACKGROUND Anti-Müllerian hormone (AMH) is a promising marker of ovarian reserve. The aim of the study is to assess the circadian variation in AMH, and to evaluate its clinical relevance and biological aspects as an effect of age and other endocrine mechanisms involved in the regulation of AMH secretion. METHODS Nineteen healthy non-smoking, regularly menstruating female volunteers with body mass

OBJECTIVE: To evaluate the early and intermediate outcome of a consecutive series of emergency endovascular aneurysm repairs (eEVAR) of computed tomography (CT)-verified infrarenal ruptured abdominal aortic aneurysm (rAAA) at a single tertiary referral centre. METHODS: Prospectively collected data of patients operated between April 2000 and October 2007 were retrospectively reviewed and all their

The purpose of this study was to derive calibration coefficients (in terms of cps kBq-1) and minimum detectable activities, MDA, (in terms of kBq and corresponding dose rate) for the dual head gamma camera part of an SPECT/CT-instrument when used for in vivo internal contamination measurements in radiation emergency situations. A cylindrical-conical PMMA phantom with diameters in the range of 7-30

Two new vectors are described, the expression vector pB3 PGK and the CRE recombinase vector pCRE3. The pB3 PGK has a zeocin-selectable marker flanked by loxP sequences and an expression cassette consisting of the strong PGK1 promoter and the GCY1 terminator. The S. cerevisiae genes RKI1, RPE1, TAL1 and TKL1 were cloned in pB3 PGK and integrated in the locus of the respective gene, resulting in ove

Background Type 2 diabetes (T2D) is a multifactorial disease in which environmental triggers interact with genetic variants in the predisposition to the disease. A number of common variants have been associated with T2D but our knowledge of their ability to predict T2D prospectively is limited. Methods and Findings By using a Cox proportional hazard model, common variants in the PPARG (P12A), CAPN

A rising global population and demand for protein-rich diets are increasing pressure to maximize agricultural productivity. Rising atmospheric [CO2] is altering global temperature and precipitation patterns, which challenges agricultural productivity. While rising [CO2] provides a unique opportunity to increase the productivity of C-3 crops, average yield stimulation observed to date is well below

The purpose of this investigation was to evaluate the role of corticotropin releasing factor (CRF) on micturition. CRF is involved in the endocrine and central nervous system responses to stress and is also expressed in sites responsible for the control of micturition. In this investigation, cystometric experiments were performed in awake and unrestrained Wistar rats and on Spontaneous Hypertensiv

In this pilot study, the predictive value of Octreotide scintigraphy (Octreoscan) and/or Chromogranin-A (CgA) was investigated in patients with hormone-refractory prostate cancer treated with Octreotide acetate. In total, 20 patients with progressive disease and bone metastases entered the trial. At baseline Octreoscan, CgA, PSA, alkaline phosphates (ALP) and two self-administered questionnaires (

Complex traits, including inflammatory rheumatic diseases, have important genetic features, but most of the responsible genes have not been conclusively identified. Genetic analysis of inbred animal models and comparative genetics - the comparison of genes between different species - might help to identify the crucial genes and to investigate more directly the biology involved. Genome-wide linkage

The combined contribution to highway safety of pavement surface and geometric design indicators is not well investigated due to the complexity of data collection and high time variability of pavement surface conditions. Introduction of high efficiency equipment for comprehensive road surveys is mitigating this issue, expanding possibilities of data integration. In this framework, the present study

Vegetable oils and fats are major energy sources but also play an essential part in the physical and chemical properties of food products. The current change in the climate is affecting harvest yields, leading to a shortage and increased prices of raw materials that are difficult to replace. In addition, there is an increasing demand for new products with positive health effects.Triacylglycerols (

The MM500 meta-study aims to establish a knowledge basis of the tumor proteome to serve as a complement to genome and transcriptome studies. Somatic mutations and their effect on the transcriptome have been extensively characterized in melanoma. However, the effects of these genetic changes on the proteomic landscape and the impact on cellular processes in melanoma remain poorly understood. In thi

Introduction: Although ischemic stroke incidence has decreased in Sweden over the past decade, trends in spontaneous intracerebral hemorrhage (ICH) incidence are less well delineated. In this time period, there has been a dramatic increase in use of oral anticoagulants (OAC). The aim of our study was to investigate incidence trends in spontaneous first-ever ICH in Sweden between 2010 and 2019, wit

Recent research on normal human tissues identified omnipresent clones of cells, driven by somatic mutations known to be responsible for carcinogenesis (e.g., in TP53 or NOTCH1). These new insights are fundamentally changing current tumor evolution models, with broad oncological implications. Most studies are based on surgical remnant tissues, which are not available for many organs and rarely in a