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Survival, migration and neuronal differentiation of human fetal striatal and cortical neural stem cells grafted in stroke-damaged rat striatum

Stroke is a neurodegenerative disorder and the leading cause of disability in adult humans. Treatments to support efficient recovery in stroke patients are lacking. Several studies have demonstrated the ability of grafted neural stem cells (NSCs) to partly improve impaired neurological functions in stroke-subjected animals. Recently, we reported that NSCs from human fetal striatum and cortex exhib

Steam pretreatment of acid-sprayed and acid-soaked barley straw for production of ethanol

Barley is an abundant crop in Europe, which makes its straw residues an interesting cellulose source for ethanol production. Steam pretreatment of the straw followed by enzymatic hydrolysis converts the cellulose to fermentable sugars. Prior to pretreatment the material is impregnated with a catalyst, for example, H2SO4, to enhance enzymatic digestibility of the pretreated straw. Different impregn

Interleukin-2-administration intravenously and intrapleurally in a patient with primary pulmonary adenocarcinoma. Cellular responses in peripheral blood, intrapleural fluid and bronchoalveolar lavage

A case report of a patient who suffered from a rapidly progressive lung adenocarcinoma with malignant pleural effusions, is given. The patient failed to respond on two series of conventional cytotoxic drug therapy (Carboplatin, Etoposid). Interleukin-2 (IL-2) treatment was first started as intrapleural instillations (3.0 million IU per day in 6 days). A clear clinical response was achieved with ce

ADHD in adult psychiatry. Minimum rates and clinical presentation in general psychiatry outpatients.

The objective of the study was to determine the prevalence and comorbidity of persisting attention-deficit hyperactivity disorder (ADHD) in adult psychiatric outpatients. Consecutive patients, first visits excluded, at a general psychiatric outpatient clinic were offered a screening for childhood ADHD with the Wender Utah Rating Scale (WURS). One hundred and forty-one patients out of 398 (35%) com

Human short-term repopulating cells have enhanced telomerase reverse transcriptase expression.

Telomerase activity has been suggested to be critically involved in hematopoietic stem cell (HSC) self-renewal. However, it has been unclear whether human HSCs have telomerase activity and how telomerase activity is regulated within the HSC and progenitor pool. Here, we isolated living cord-blood (CB) CD34+ cells with up-regulated human telomerase reverse transcriptase (hTERT) expression by using

On Sustainability in Local Energy Planning

Popular Abstract in English Human life in general, depends on having access to useable forms of energy for meeting the basic needs such as preparation of food and provision a comfortable place to live. Energy is also necessary for running the societal services for instance, transportation, health care and education. It is important to know what energy resources are available, how much energy is nEnergy is among the main driving forces needed for sustainable development. Provision of energy services, from the supply side to transmission/distribution and use, must include management, and good management requires tools. Energy planning is a tool for managing the community energy system through assessing and balancing supply and demand. This thesis explains an approach to energy planning whic

Mast-cell-dependent secretion of CXC chemokines regulates ischemia-reperfusion-induced leukocyte recruitment in the colon.

BACKGROUND AND AIMS: Recruitment of leukocytes in the tissue microvasculature is considered to be a rate-limiting step in ischemia-reperfusion (I/R)-induced inflammation. The objective of this study was to examine the role of mast cells in CXC-chemokine- and I/R-provoked leukocyte recruitment in the colon. MATERIALS AND METHODS: Balb/c- and mast-cell-deficient mice were challenged with the CXC che

Performance and emissions of diesel-biodiesel-ethanol blends in a light duty compression ignition engine

An approach to reduce CO2 emissions while simultaneously keeping the soot emissions down from compression ignition (CI) engines is to blend in short chained oxygenates into the fuel. In this work, two oxygenated fuel blends consisting of diesel, biodiesel and EtOH in the ratio of 68:17:15 and 58:14:30 has been utilized and studied in a single cylinder light duty (LD) CI engine in terms of efficien

Dietary fibre production from oat hulls

The current threats of climate change connected to the unsustainable consumption of fossil resources paired with an increasing world population demands the exploration of alternative raw materials for the production of food, fuel and specialty chemicals. Agricultural waste streams present suitable sources due to their availability in large quantities at low costs without competing with current foo

Colectomy incidence rates in five-year data from the observational postmarketing ulcerative colitis study of originator infliximab

Background: This analysis of the Observational Postmarketing Ulcerative Colitis Study examined incidence rates of colectomy in patients with ulcerative colitis who received originator infliximab (IFX) or conventional therapies (ConvRx) as per their treating physician. Methods: Cox proportional hazards models compared time to colectomy for both treatment groups. A secondary analysis examined colect

Microbial test organisms for sterilization processes in food industry

The importance of sterilization processes has been a major topic in the food manufacturing industry since it preserves the quality and provides longer shelf-life by preventing microbiological recontamination of products. Aseptic packaging is an alternative technique to pack commercially sterile products into containers with a very low recontamination rate, thus, the entire production chain must be

Testicular torsion Point-based Assessment and Imaging tool-identifying Need for Surgical exploration (TPAINS) : a clinical algorithm for detecting testicular torsion

Objective: Testicular torsion (TT) is a medical emergency, difficult to identify solely through clinical evaluation. This study aims to develop an assessment algorithm with a safe lower threshold for complementary ultrasound. Material and methods: Males between 1 and 30 years of age assessed for suspected TT during the years 2019 – 2023 were retrospectively included. Clinical assessments were cond

Consumer Rights and Human Rights: A Study of the Relationship between the Right to Safe Food Products and International Human Rights Law

Unsafe food consumption is an alarming issue worldwide which is linked to the fatalities of two million people annually. Such unsafe food intertwines with the right to health of consumers in a way that every individual is ubiquitously a consumer at one point in their life and safe food is one of the determinants of the right to health. Hence, the right to safe food and the right to health of consu

False promise or promise with a fault : deciphering the effectiveness of eco-label governance in the german textile market

An understanding of the inherent effectiveness-potential of environmental product-labels is important because of the growing presence of these labels as governance regimes, especially in the textile market. The proper governance of eco-labels has the potential to assist with the transformation to more environmentally friendly consumption, but not enough is known about the inherent qualities that m

Safety Evaluation and Growth Optimisation of a New Probiotic

Gut microbiota play a central role in metabolism for example in blood glucose homeostasis and appetite regulation. This thesis provides a prospect of using the bacterium Prevotella copri as a probiotic to help maintain a healthy gut microbiota as many evidences points towards probiotics to have a great potential as preventative agents or therapeutics for type 2 diabetes. In the first part of the tAccording to the World Health Organization (WHO) nearly 8.5% of the global population is affected by metabolic diseases such as type 2 diabetes and obesity which are one of the major causes of death and disability worldwide. This causes a huge financial burden on the healthcare system globally. Therefore, there is an urgent need to prevent, delay and treat these diseases and their debilitating com

Framtagning av BIM-objekt för byggsystemleverantörer, undertaksystem från Ecophon

Background BIM, Building Information Modelling, is a relatively new approach to work with building design and information management within the building industry. As higher demands are placed on product information and information management, manufacturers of building materials have to meet the need for BIM objects and 3D modeling. Ecophon is a supplier of sound absorbing ceilings and wall absorbe

Mycobacterium marinum promotes mitochondrial degradation in an ESX-1 dependent manner

Investigating the role of mitochondrial damage in a Tuberculosis infection Tuberculosis (TB) is a significant health risk that was responsible for 10.4 million infections and 1.8 million deaths in the year 2015 alone. The causative agent for TB is Mycobacterium tuberculosis (Mtb), which is an intra-cellular bacterium that primarily replicates within the white blood cell called the macrophage. To

Återvunnen polyester från PET-flaskor: En jämförande resurseffektivitetsanalys av återvinningsvägarna flaska-till-flaska och flaska-till-fiber

I övergången till en cirkulär ekonomi använder industrier i allt högre grad återvunnet material för att minska klimatpåverkan från sina produkter. Den ökade efterfrågan på återvunnet material drivs av både EU-direktiv och konsumenters preferenser. Både flask- och polyesterfiberindustrin ser potential i att möta EU:s krav och konsumenters efterfrågan genom att ersätta jungfruligt material med återvIn the transition towards a circular economy, industries are increasingly adopting recycled materials to decrease the climate impact of their products, driven by both regulatory requirements and consumer demand. The bottle and polyester fiber industries both recognize the potential to comply with EU policies and consumer preferences by replacing virgin material with recycled PET. Due to its desira

3D Printed Photocatalytic Spacers Integrated with Membrane Filtration for Degradation of Persistent Organic Micropollutants

Certain organic micropollutants and emerging contaminants are increasingly detected in wastewater effluents due to enhancement of detection techniques and new technological processes or household items being introduced. Some of them can accumulate in food chains and/or pose health risks for humans, wildlife and ecosystems. Often, these are very difficult or impossible to sufficiently remove using

Olive yield forecasting from remote sensing and climate datasets in the Jaen province (Spain)

The severe decline in olive oil production recorded in the last years is having an economic impact on many Mediterranean countries. The aim of this MSc thesis is to predict the olive yield by means of satellite vegetation indices and meteorological data mostly retrieved by satellite remote sensors. Estimating olive yield production using remote sensing data is reasonably new as few scientific pape