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The purpose of this thesis is to investigate an alternative way of management within physical systems engineering development (PSED), a term which represents all fields of engineering where physical components are involved. More specifically, analysing how agile methodologies can be applicable with the use of technological advancements to overcome the restrictions hindering the increase of efficie
Bostäder består antingen av hela fastigheter eller av delar av fastigheter. Fastigheter och deras priser är intressanta i förhållande till andra varor då de är knutna till en precis lokalisering. Priset på en fastighet säger mycket om värdet av den lokalisering som fastigheten har. För en stad är prisutvecklingen en slags temperaturmätare och speglar en förändring i attraktivitet för ett visst lägReal estate and its prices are interesting in relation to other goods due to the strong linkage to a precise location. The price of a property says a lot about the value of its location. For a city, price development is a strong indicator and reflects a change in attractiveness for a particular location. The purpose of this Master Thesis is to explain the deviation in price development on dwellin
Relapsed or recurrent breast cancer is the chief cause of breast cancer related deaths and it is estimated that one-third of breast cancer patients would likely suffer a relapse. Due to high mortality and incidence, recurrent breast cancer requires better means of prediction, prevention and treatment. The AFFIRM platform uses recombinant antibody technology and selected reaction monitoring (SRM) m
The use of reliable distance estimates is key to derive accurate three-dimensional velocities of celestial objects. Systematic overestimation and large uncertainties in the distances will thus provide misleading information of an object's kinematics. In turn, astronomers will get a flawed understanding of dynamical properties of substructures in the Milky Way. In this paper, we employ the imp
Området för läkemedelsutveckling genom kliniska prövningar står inför stora utmaningar i och med tillämpningen av EU:s nya dataskyddsförordning, GDPR. Förordningen ska tillämpas på all behandling av personuppgifter som sker inom EU eller kopplat till unionen. Detta får enorm påverkan på alla organisationer som hanterar personuppgifter, inom alla branscher. Den organisation som handlar i strid mot The area of drug development through clinical trials is facing major challenges in the application of the EU's new data protection regulation, GDPR. The Regulation applies to all processing of personal data that occurs within the EU or linked to the Union. This causes a significant impact on all organizations that handle personal data, in all industries. Organizations not acting in accordanc
Adaptation of modern Unmanned Aerial Vehicle (UAV) and multispectral sensor technology in agriculture can enhance the capacity to accurately monitor crops. But these technologies come with its own set of challenges. The major challenge is the understanding of radiometric distortions, which is particularly important while comparing data over different lighting conditions. The study developed and as
With better understanding of the properties and mechanical behavior of wood fiber composites such as wood particle boards the final structure can be improved, both from a solid mechanical and cost effective perspective. Particle boards are widely used in today’s industry for consumer products and the mechanical properties for such materials and how it is effected by the mix of wood chips and glue
Aim/hypothesis: Environmental factors are believed to contribute to the risk of developing type 1 diabetes. The aim of this study was to investigate how size for gestational age affects the risk of developing childhood type 1 diabetes. Methods: Using the Swedish paediatric diabetes quality register and the Swedish medical birth register, children with type 1 diabetes diagnosed between 2000 and 201
AIMS: Patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) have increased prevalence of atrial arrhythmias indicating atrial involvement in the disease. We aimed to assess the long-term evolution of P-wave indices as electrocardiographic (ECG) markers of atrial substrate during ARVC progression. METHODS AND RESULTS: We included 100 patients with a definite ARVC diagnosis according
Purpose: Presence of disseminated tumour cells (DTCs) in the bone marrow (BM) has been described as a surrogate of residual disease in patients with early breast cancer (EBC). PADDY (Pooled Analysis of DTC Detection in Early Breast Cancer) is a large international analysis of pooled data that aimed to assess the prognostic impact of DTCs in patients with EBC. Experimental design: Individual patien
BACKGROUND: Radon is an inert gas formed from the decay of naturally-occurring materials in the earth's crust. It infiltrates into homes from soil, water, and construction materials. Its decay products are radionuclides, which attach to ambient particles. Residential radon is one of the leading risk factors for lung cancer. The scarce evidence for associations with other mortality causes originate
β-Mannanases catalyze the conversion and modification of β-mannans and may, in addition to hydrolysis, also be capable of transglycosylation which can result in enzymatic synthesis of novel glycoconjugates. Using alcohols as glycosyl acceptors (alcoholysis), β-mannanases can potentially be used to synthesize alkyl glycosides, biodegradable surfactants, from renewable β-mannans. In this paper, we i
Background: Although advances in the treatment of myeloid neoplasms have led to improved patient survival, this improvement has been accompanied by an increased risk of second primary cancer (ie, the risk of another cancer after myeloid neoplasia). We aimed to assess bi-directional associations between myeloid cancers and other cancers—ie, development of second primary cancer in patients who have
OBJECTIVE: To conduct a study on attitudes, knowledge, and use of complementary and alternative medicine (CAM) therapies in Serbia. Available data about CAM therapies in the region are scarce, opinions lacking from health sector. Balkan region countries had a delay in issuing national policies on CAM therapies.METHODS: The questionnaire used was based on previously validated CAM Health Belief Ques
Head and neck skin cancer surgery using a full thickness skin graft is a common procedure. Evidence concerning the effects of perioperative antithrombotic treatment on complications is limited. The aim of this study was to evaluate whether perioperative antithrombotic treatment is associated with risk of necrosis, bleeding or infection after full thickness skin graft surgery. Retrospective single-
The expression of platelet-derived growth factor (PDGF) receptors in porcine uterus and human skin in situ, was compared with that of cultured primary cells isolated from the same tissues. PDGF receptor expression was examined by monoclonal antibodies specific for the B type PDGF receptor and by RNA/RNA in situ hybridization with a probe constructed from a cDNA clone encoding the B type PDGF recep
Biogenic volatile organic compounds (BVOC), such as isoprene and monoterpenes, play an important role in atmospheric processes. BVOC species are oxidized in the atmosphere and influence levels of ozone. The less volatile amongst the BVOC and their oxidation products are important for the formation and growth of secondary biogenic aerosol. In this way, the Earth's radiation balance is affected. Geo
Vitreoscilla is an obligate aerobic bacterium found in oxygen-poor environments such as stagnant ponds and decaying vegetable matter. Vitreoscilla induces the production of a homodimeric hemoglobin (VHb) when subjected to oxygen-limiting conditions. It is thought that VHb facilitates oxygen delivery to the respiratory apparatus of its host by increasing the local oxygen concentration under oxygen-
New and innovative production equipment can be developed by introducing lightweight materials in modern day automotive industry production lines. The properties of these new materials are expected to result in improved ergonomics, energy savings, increased flexibility and more robust equipment, which in the end will result in enhanced productivity. Carbon composite materials are one such alternati
BACKGROUND: Persistent organochlorine pollutants (POPs) may interfere with reproductive function but direct evidence in humans is very limited. METHODS: Fertility was examined in four regions with contrasting blood levels of POPs. Pregnant women and their partners in Warsaw (Poland), Kharkiv (Ukraine) and Greenland were consecutively enrolled during antenatal visits. Swedish fishermen and their sp
