Filetype
The aim of this study was to determine in patients with HCV genotype 2 or 3 the performance at week 4 of two assays with different sensitivities for HCV RNA detection, for the prediction of SVR and stratification for treatment duration (14 and 24 weeks). Recruitment was from two trials comparing 14 and 24 weeks treatment to patients with rapid virological response (RVR) (n = 550). RVR was original
The jet energy scale and its systematic uncertainty are determined for jets measured with the ATLAS detector at the LHC in proton-proton collision data at a centre-of-mass energy of root s = 7 TeV corresponding to an integrated luminosity of 38 pb(-1). Jets are reconstructed with the anti-k(t) algorithm with distance parameters R = 0.4 or R = 0.6. Jet energy and angle corrections are determined fr
Popular Abstract in Swedish Arbetet i denna avhandling presenteras i 6 olika delarbeten (artiklar I-VI). Artiklarna I-III behandlar två olika enzymer som bryter ner cyklodextriner, vilka är ringformade molekyler med samma beståndsdelar som i stärkelse (dvs sammanlänkade glukosmolekyler). Dessa s.k. cyklodextrinaser kommer ursprungligen från två bakterier som har isolerats i varma källor på Island.Two putative cyclodextrinases (CDases) were amplified from two moderate thermophiles isolated in Iceland: Anoxybacillus flavithermus and Laceyella sacchari. They were cloned, expressed and characterized. The expression of the former was optimized in E. coli by using a solubility-enhancing tag, NusA, and tuning of inducer concentration in the expression strain Tuner(DE3). The CDases were optimally
With the exponential growth of the World Wide Web, automated subject classification has become a major research issue. Organizing web pages into a hierarchical structure for subject browsing has been gaining more recognition as an important tool in information-seeking processes.The most frequent approach to automated classification is machine learning. It, however, requires training documents and
Vitreoscilla is an obligate aerobic bacterium found in oxygen-poor environments such as stagnant ponds and decaying vegetable matter. Vitreoscilla induces the production of a homodimeric hemoglobin (VHb) when subjected to oxygen-limiting conditions. It is thought that VHb facilitates oxygen delivery to the respiratory apparatus of its host by increasing the local oxygen concentration under oxygen-
New and innovative production equipment can be developed by introducing lightweight materials in modern day automotive industry production lines. The properties of these new materials are expected to result in improved ergonomics, energy savings, increased flexibility and more robust equipment, which in the end will result in enhanced productivity. Carbon composite materials are one such alternati
In this thesis, I study representations of summer and winter Olympic Games and Olympic athletes in six Swedish popular magazines 1948-1972. The purpose is to examine the forms of identity produced within the nation as an “imagined community”, in discursive processes where gender, sexuality, ”race”/ ethnicity, class and age/generation intersect and mutually construct each other. The study is inspir
Background: Mental distress is a major public health problem which includes anxiety, depression and somatic symptoms such as sleeping problems, fatigue and headache. University students are consistently reported to have higher levels of mental distress compared to the general population. Although university students with mental distress have significantly impaired cognitive functioning, learning d
Sediments from the only permanent lake on the island of Jan Mayen (71°N, 08°30′W), Lake Nordlaguna (NL), were investigated. The lake, with an area of ∼1 km2, is situated at the foot of the world's northernmost active subaerial volcano and is separated from the sea by a 150–240 m wide beach barrier, which reaches 4–5 m above sea level. Most of the lake is deeper than 25 m, with the deepest part bei
Objective: To compare women's perspectives on the quality of maternal and newborn care (QMNC) around the time of childbirth across Nomenclature of Territorial Units for Statistics 2 (NUTS-II) regions in Portugal during the COVID-19 pandemic. Methods: Women participating in the cross-sectional IMAgiNE EURO study who gave birth in Portugal from March 1, 2020, to October 28, 2021, completed a structu
Compact dual-polarization doppler X-band weather radars (X-WRs) have recently gained attention in Scandinavia for sub-km and minute scale rainfall observations. This study develops a method for merging data from two X-WRs in Dalby and Helsingborg, southern Sweden (operated at five and one elevation angle levels, respectively) to improve the accuracy of rainfall observations. In total, 87 rainfall
BACKGROUND: Persistent organochlorine pollutants (POPs) may interfere with reproductive function but direct evidence in humans is very limited. METHODS: Fertility was examined in four regions with contrasting blood levels of POPs. Pregnant women and their partners in Warsaw (Poland), Kharkiv (Ukraine) and Greenland were consecutively enrolled during antenatal visits. Swedish fishermen and their sp
The effects of data uncertainty in applications of the critical loads concept were investigated on different spatial resolutions in Sweden and northern Czech Republic. Critical loads of acidity (CL) were calculated for Sweden using the biogeochemical model PROFILE. Three methods with different structural complexity were used to estimate the adverse effects of SO2 concentrations in northern Czech R
OBJECTIVES: To investigate whether application of insulation wool adversely affects lung volumes and increases the occurrence of symptoms of airway irritation. METHODS: Data from nationwide health check ups in 1981-93 of male construction workers born in 1955 or later were used to investigate cross sectional (n = 96,004) and longitudinal (n = 26,298) associations between lung volumes, vital capaci
Context. Gaia Data Release 1 (DR1) contains astrometric results for more than 1 billion stars brighter than magnitude 20.7 based on observations collected by the Gaia satellite during the first 14 months of its operational phase. Aims. We give a brief overview of the astrometric content of the data release and of the model assumptions, data processing, and validation of the results. Methods. For s
Bank voles are known reservoirs for Puumala hantavirus and probably also for Ljungan virus (LV), a suggested candidate parechovirus in type 1 diabetes etiology and pathogenesis. The aim of this study was to determine whether wild bank voles had been exposed to LV and if exposure associated to autoantibodies against insulin (IAA), glutamic acid decarboxylase 65 (GADA), or islet autoantigen-2 (IA-2A
Echolocating bats are surveyed and studied acoustically with bat detectors routinely and worldwide, yet identification of species from calls often remains ambiguous or impossible due to intraspecific call variation and/or interspecific overlap in call design. To overcome such difficulties and to reduce workload, automated classifiers of echolocation calls have become popular, but their performance
In the evolution of bird migration, partial migration is assumed to be an important intermediate step between migration and residency. Partial migration is characterised by the existence of both migratory and resident individuals in a given population. Compared to regular migration, relatively little is known about partial migrants and their migratory performances. In my thesis, I have studied th
Background: Physical and biological properties of dust particles might affect the availability and distribution of chemicals associated to indoor dust; however it has not been adequately examined. In this study, household dust from Shanghai was fractionated into five particle sizes and size distribution, morphology, surface area, organic matter, microorganisms, elemental composition, metals and or
Glutaric aciduria type III is a rare metabolic abnormality leading to persistent isolated glutaric acid excretion. We report the clinical and biochemical phenotypes of three affected children. The first patient is a boy with dysmorphic features and a chromosomal deletion (monosomy 6q26-qter) in whom a persistent glutaric aciduria (500mmol/mol creatinine, normal <10) was detected during a routine m
