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Popular Abstract in Swedish Alla levande organismer består av celler som tillsammans med molekyler generellt kallade extracellulär matrix bildar en vävnad. Celler innehåller fyra huvudgrupper av byggstenar: socker, fettsyror, aminosyror och nukleotider, vilka i tur och ordning bildar kolhydrater, fetter, proteiner och nukleinsyror. I vävnaderna pågår en ständig omsättning av byggstenarna och molekThis thesis describes structural and functional studies of alpha-1-microglobulin (a1m), a 26 kDa plasma and tissue protein that is evolutionarily well-conserved and belongs to the lipocalin superfamily. The lipocalins are polypeptides of 160-190-amino acids that are folded into an 8-stranded beta-barrel forming a pocket with a hydrophobic interior. a1m carries heterogeneous yellow-brown chromophor

Background. Bioincompatible glucose degradation products (GDPs) in fluids for peritoneal dialysis (PD) develop during sterilization and storage. Their biological activity has successfully been monitored through the use of various in vitro methods but their molecular and chemical nature is less well understood. Many GDPs are highly reactive carbonyl compounds. Although some of the identified GDPs a

The principal fate during litter decomposition and mineralization is rather well established only for a limited number of elements, mainly essential plant nutrients and a few potentially very toxic metals. Elements which occupy the majority of the positions in the periodical system seems almost unknown in this context. The objectives were, therefore to assess differences in the behavior of 58 mine

Background: Ovarian tumours are usually surgically removed because of the presumed risk of complications. Few large prospective studies on long-term follow-up of adnexal masses exist. We aimed to estimate the cumulative incidence of cyst complications and malignancy during the first 2 years of follow-up after adnexal masses have been classified as benign by use of ultrasonography. Methods: In the

Background: Hyperuricemia (HU) is in the causal pathway for developing clinical gout. There are few population-based assessments of the absolute and relative risk of clinically diagnosed incident gout in subjects with HU. We aimed to explore the long-term risk of developing incident gout among asymptomatic adults with different levels of serum urate (SU). Methods: Malmö Preventive Project was a po

In my paper I have emanated from the question when a refusal to deal by an undertaking in a dominant position constitutes an abuse according to article 82 EC Treaty. Article 82 of The Consolidated version of the Treaty establishing the European Community, signed in Rome 1957, incorporating the changes made by the Treaty of Amsterdam on 2 October 1997, OJ 1997 C340, pp. 173-308, hereafter referred

Interference fit assembly is a state-of-the-art technology for mounting cylindrical shafts into bores. Due to its extreme cost-efficiency it is used even in high-tech applications such as one of Bosch’s gasoline flow controllers. The picture below shows the anchor-needle connection. Due to electromagnetic incitation the assembly oscillates over 55 times per second. In order for the assembly to wit

Genom EU-domstolens banbrytande avgörande i UsedSoft 2012 bekräftades att konsumtion av spridningsrätten kan ske till digitala kopior av datorprogram, förutsatt att kraven för en ”första försäljning” enligt artikel 4.2 dator-programdirektivet uppfylls. Domen innebar slutpunkten för den vedertagna uppfattningen att spridning av digitala verk ska klassificeras som tjänster, för vilka konsumtionsprinIn 2012, the CJEU confirmed in the landmark UsedSoft case, that the right of distribution right in regards to digital copies of computer program can be exhausted, provided that the requirements for a “first sale” according to Article 4.2 of the Software Directive is met. The ruling put an end to a previous ion that the distribution of digital copies of copyrighted works is considered as a service

By studying different types of ovens, both new and old I created a suggestion for an interface applicable to future ovens in the IKEA oven range. In order to create interactive appliances with the advanced technology existing today I believe we have to look back. The complex possibilities created by the availability of LED and touchscreens have made the daily cooking harder for “the many people”.

This work describes the degradation of nonylphenol, toxaphene, phenanthrene, benzo[a]pyrene and dyes using fungi and their redox enzymes. Two fungi, Bjerkandera sp. strain BOL13 and Fusarium sp. strain BOL35 were isolated from different geographic area in Bolivia. They were characterized genetically, physiologically and biochemically. Degradation of nonylphenol by Bjerkandera sp. strain BOL13 and

The urbanization of landscapes and the increase in impervious land cover materials is known to cause significant changes in the landscape's thermal properties, typically leading to urban heat island (UHI). Although previous studies have investigated the impacts of land cover land use (LULC) and other factors on the urban land surface temperature (LST), the results of such studies are mixed. For in

Future global temperature change will have significant effects on society and ecosystems. Earth system models (ESM) are the primary tools to explore future climate change. However, ESMs have great uncertainty and often run at a coarse spatial resolution (usually about 2°). Accurate high-spatial-resolution temperature dataset are needed to improve our understanding of temperature variations and for

This dissertation discusses mainly new cryptanalytical results related to issues of securely implementing the next generation of asymmetric cryptography, or Public-Key Cryptography (PKC).PKC, as it has been deployed until today, depends heavily on the integer factorization and the discrete logarithm problems.Unfortunately, it has been well-known since the mid-90s, that these mathematical problems

Retention in prevention of mother-to-child transmission (PMTCT) care is critical to prevent vertical HIV transmission and reduce morbidity and mortality of mother-infant pairs. We investigated whether weekly, interactive text-messaging improved 18-month postpartum retention in PMTCT care. This randomised, two-armed, parallel trial was conducted at six PMTCT clinics in western Kenya. Pregnant womenRetention in prevention of mother-to-child transmission (PMTCT) care is critical to prevent vertical HIV transmission and reduce morbidity and mortality of mother-infant pairs. We investigated whether weekly, interactive text-messaging improved 18-month postpartum retention in PMTCT care. This randomised, two-armed, parallel trial was conducted at six PMTCT clinics in western Kenya. Pregnant women

Aims/hypothesis: Regulatory factor X 6 (RFX6) is crucial for pancreatic endocrine development and differentiation. The RFX6 variant p.His293LeufsTer7 is significantly enriched in the Finnish population, with almost 1:250 individuals as a carrier. Importantly, the FinnGen study indicates a high predisposition for heterozygous carriers to develop type 2 and gestational diabetes. However, the precise

Lärares praktiska yrkeskunskaper bjuder motstånd mot förspråkligande. Detta problem föreligger inte minst i lärarutbildningen, där det i verksamhetsförlagda delar kan råda både osäkerhet och skilda uppfattningar om vad studenterna behöver göra eller prestera för att uppnå de mål som (bokstavligen) föreskrivits dem. Syftet med avhandlingen har varit att beskriva och förstå villkor och förutsättningTeachers' practical professional skills offer resistance to advocacy. This problem exists not least in teacher education, where in work-based parts there can be both uncertainty and different perceptions of what the students need to do or perform in order to achieve the goals that are (literally) prescribed for them. The purpose of the dissertation has been to describe and understand conditions an

Aims. We study the dynamics and growth of dust particles in circumstellar disks of different masses that are prone to gravitational instability during the critical first Myr of their evolution. Methods. We solved the hydrodynamics equations for a self-gravitating and viscous circumstellar disk in a thin-disk limit using the FEOSAD numerical hydrodynamics code. The dust component is made up of two

Bread dough was studied in relation to three Andean grain flours, quinoa (Chenopodium quinoa), amaranth (Amaranthus caudatus) and canahua (Chenopodium pallidicaule), as partial replacements for wheat flour with the perspectives of dough and breadmaking. This thesis deals with the understanding of both dough as a complex system, consisting of various water-filled polymers, and dough as a viscoelast

Well before large-scale quantum computers will be available, traditional cryptosystems must be transitioned to post-quantum (PQ) secure schemes. The NIST PQC competition aims to standardize suitable cryptographic schemes. Candidates are evaluated not only on their formal security strengths, but are also judged based on the security with regard to resistance against side-channel attacks. Although r

The need for increaseding accuracy and reduced ambiguities in the inversion results has resulted in focus on the development of more advanced inversion methods of geophysical data. Over the past few years more advanced inversion techniques have been developed to improve the results. Real 3D-inversion is time consuming and therefore often not the best solution in a cost-efficient perspective. This