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Streptococcus pyogenes infects over 700 million people worldwide annually. Immune evasion strategies employed by the bacteria include binding of the complement inhibitors, C4b-binding protein (C4BP) and Factor H in a human-specific manner. We recently showed that human IgG increased C4BP binding to the bacterial surface, which promoted streptococcal immune evasion and increased mortality in mice.

Pyranose 2-oxidase (P20x) has several proposed biotechnological applications such as a bio-component in biofuel cells or for carbohydrate transformations. To improve some of the catalytic properties of P20x from Trametes multicolor, we selected a semi-rational approach of enzyme engineering, saturation mutagenesis of active-site residues and subsequent screening of mutant libraries for improved ac

Despite systematic screening and improved treatment strategies, the prognosis remains worse in patients with connective tissue disease-associated pulmonary arterial hypertension (CTD-PAH) compared to patients with idiopathic/hereditary pulmonary arterial hypertension (IPAH). We aimed to investigate differences in clinical characteristics, outcome and performance of the European Society of Cardiolo

June visits and summer greetings! June visits and summer greetings! Published 20 June 2024 Summer is approaching (or is already here), and the lab has had an intense spring that culminated in many prominent visits in June! We've had so many exciting questions and discussions with everyone, and we feel proud and happy to have such a fantastic operation to showcase and share with others. Here are so

https://www.humlab.lu.se/article/june-visits-and-summer-greetings/ - 2026-07-21

The present article describes data from pilot studies with the Swedish versions of the Mindful Attention Awareness Scale (MAAS) and the Kentucky Inventory of Mindfulness Skills (KIMS). The MAAS and two of the KIMS scales, Act with Awareness and Accept without Judgment, were found to correlate in the predicted direction with measures of well-being and emotional distress. The KIMS scales Observe and

Background: Systemic Lupus Erythematosus (SLE) is an autoimmune disease encompassing a wide range of symptoms that can emanate from pathology in virtually any organ system. Severe SLE includes involvement of the central nervous system and kidneys. One of the hallmarks of the disease is a multitude of autoantibodies, indicating a breakdown in self tolerance. The corresponding antigens have been fou

In everyday conversations, we frequently give an example. Yet this is seldom accompanied by any reflection on what is going on when we do so. This report tries to contribute such a reflection. It shows how examples may be marked and used in a particular discourse: oral discourse on others. The empirical material is a transcribed focus group interview with a group of Swedish students, engaged in di

Background Monitoring labor and childbirth, early recognition, and treatment of complications are critical for preventing adverse birth outcomes. However excessive use of interventions during labor has not been demonstrated to enhance subsequent birth outcomes and may, in fact, pose a risk of harm. The World Health Organization has recently synthesized research from the last decade concerning labo

Prekonceptionell hälsa och rådgivning Kvinnor och mäns levnadsvanor inför graviditet påverkar fostret och det blivande barnets hälsa. Under våren 2019 ges en utbildning i Prekonceptionell hälsa och rådgivning vid Lunds universitet. Utbildningen är den första kursen i Sverige inom prekonceptionell hälsa, vilket gör den unik i sitt slag. Den riktar sig till barnmorskor generellt, och i synnerhet til

https://www.medicin.lu.se/sites/medicin.lu.se/files/prekonceptionell_halsa_20181218.pdf - 2026-07-22

2023-09-25 Protokoll LSK Sida 1 av 5 Lokal skyddskommitté PROTOKOLL Diarienummer V 2023/2095 Datum 2023-09-25 Protokoll lokal skyddskommitté Närvarande Karin Hall, stf ordförande Catrin Malmström, kansli N, ledamot Jessica Abbott, biologiska institutionen, ledamot Leif Bülow, kemiska institutionen, ledamot Magnus Alsterfjord, huvudskyddsombud Bengt Meuller, över- och huvudskyddsombud Carina Rasmus

https://www.naturvetenskap.lu.se/internt/sites/naturvetenskap.lu.se.internt/files/2023-12/2023-09-25%20LSK-protokoll-webb.pdf - 2026-07-22

Background: Timely treatment of acute allergic reactions (AARs) is important to minimize reaction severity. Corticosteroid tablets dissolved in water are commonly used in mainstay treatment. A new oral film that dissolves on the tongue provides a faster and less cumbersome alternative to tablets for corticosteroid administration during AARs. This study evaluated patients' preferences for attribute