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Adult height and sitting height may reflect genetic and environmental factors, including early life nutrition, physical and social environments. Previous studies have reported divergent associations for height and chronic disease mortality, with positive associations observed for cancer mortality but inverse associations for circulatory disease mortality. Sitting height might be more strongly asso

Aims/hypothesis: Sugar-sweetened beverages (SSBs) are a major dietary contributor to fructose intake. A molecular pathway involving the carbohydrate responsive element-binding protein (ChREBP) and the metabolic hormone fibroblast growth factor 21 (FGF21) may influence sugar metabolism and, thereby, contribute to fructose-induced metabolic disease. We hypothesise that common variants in 11 genes in

Background: Oxidation of LDL particles entrapped in the extracellular matrix of the arterial wall is a key factor in the development of atherosclerosis. Lipid oxidation products, such as malondialdehyde (MDA), react with surrounding extracellular matrix proteins and cause modifications that are recognized by the immune system. MDA modification of collagen type IV is increased in carotid lesions fr

Life style changes and improved medical therapy have decreased cardiovascular mortality in many countries over the last decades. This has been accompanied by changes in disease characteristics including more non-ST segment elevation myocardial infraction and less vulnerable plaques as assessed by histological analysis of surgical specimens. However, many patients with established disease still suf

Introduction: CAM2038 q1w (once weekly) and q4w (once monthly) are investigational buprenorphine subcutaneous (SC) formulations based on FluidCrystal® injection depot technology. These two drug products are being developed for opioid dependence treatment, with a target for once-weekly and once-monthly SC dosing. The rationale for developing two products with different dosing frequencies is that tr

Enzalutamide significantly improved radiographic progression-free survival (rPFS) and overall survival (OS) among men with chemotherapy-naïve metastatic castration-resistant prostate cancer at the prespecified interim analysis of PREVAIL, a phase 3, double-blind, randomized study. We evaluated the longer-term efficacy and safety of enzalutamide up to the prespecified number of deaths in the final

Background:Recent cross-sectional genome-wide scans have reported associations of 97 independent loci with body mass index (BMI). In 3541 middle-aged adult participants from the GLACIER Study, we tested whether these loci are associated with 10-year changes in BMI and other cardiometabolic traits (fasting and 2-h glucose, triglycerides, total cholesterol, and systolic and diastolic blood pressures

Aims/hypothesis: Insufficient insulin release and hyperglucagonaemia are culprits in type 2 diabetes. Cocaine- and amphetamine-regulated transcript (CART, encoded by Cartpt) affects islet hormone secretion and beta cell survival in vitro in rats, and Cart−/− mice have diminished insulin secretion. We aimed to test if CART is differentially regulated in human type 2 diabetic islets and if CART affe

BACKGROUND/OBJECTIVES:In studies performed in mice, rose hip powder has been shown to both prevent and reverse high-fat diet-induced obesity and glucose intolerance as well as reduce plasma levels of cholesterol. The aim of this study was to investigate whether daily intake of rose hip powder over 6 weeks exerts beneficial metabolic effects in obese individuals.SUBJECTS/METHODS:A total of 31 obese

Carotenoids and vitamin C are thought to be associated with reduced cancer risk because of their antioxidative capacity.

BACKGROUND: The minor T allele of rs2943641 near the gene encoding for insulin receptor substrate 1 (IRS1) has been associated with decreased risk of type 2 diabetes (T2D) and adiposity in genome-wide association studies. Dietary intake can influence the regulation of IRS1, and studies have indicated sex-specific associations between IRS1 and adiposity. OBJECTIVE: The objective was to examine the

It is well established that adaptive immune responses induced by hypercholesterolemia play an important role in the development of atherosclerosis, but the pathways involved remain to be fully characterized. In the present study we assessed immune responses to hypercholesterolemia induced by feeding Apoe-/- mice a high-fat diet for 4 or 8 weeks.

We compared the ability of genetic (established type 2 diabetes, fasting glucose, 2 h glucose and obesity variants) and modifiable lifestyle (diet, physical activity, smoking, alcohol and education) risk factors to predict incident type 2 diabetes and obesity in a population-based prospective cohort of 3,444 Swedish adults studied sequentially at baseline and 10 years later.

Citation Lindehammer SR, Fex M, Maziarz M, Hanson I, Marsal K, Lernmark Å on behalf of the Diabetes Prediction in Skåne (DiPiS) Study Group. Early-pregnancy cytokines in mothers to children developing multiple, persistent islet autoantibodies, type 1 diabetes, or both before 7 years of age. Am J Reprod Immunol 2011 Problem Increased levels of serum cytokines in early pregnancy may increase the ris

Brevmall Postadress Box 207 221 00 Lund Besöksadress Lilla Gråbrödersgatan 4 Telefon dir 046-222 10 00, växel 046-222 00 00 Telefax 046- 222 11 61 E- post info@jur.lu.se Internet http://www.jur.lu.se Jur i d i sk a fa k ul te ts s tyr e ls e ns n äm nd för u t bi ld n in g p å fors kar n ivå Kursplan för Forskarskola i rättsvetenskap, del 2 (Research School in Jurisprudence), 10 HP, Forskarnivå JU

https://www.jur.lu.se/sites/jur.lu.se/files/2025-09/JURFS20%20kursplan%202023-06-14.pdf - 2026-05-28

Microsoft Word - SAIRLA research brief 3_Agricultural transformation in Zambia.docx What drives agricultural transformation in Zambia? Lessons from a political economy analysis Anna Mdee, University of Leeds/ Overseas Development Institute and Alesia Ofori Dedaa, Overseas Development Institute June 2018 In this briefing we explore the politics and institutions of agricultural policy and implementa

https://www.keg.lu.se/en/sites/keg.lu.se.en/files/sairla_research_brief_3_agricultural_transformation_in_zambia.pdf - 2026-05-28

VATTNET VET (THE WATER KNOWS) Kezia Pritchard will present her artwork Vattnet vet (The water knows), created with the local residents of Knislinge and the surrounding areas, in the sculpture park at Wanås Konst. The presentation will include a description of the project and an insight into the artist’s research on dialogue as an art form, oral history, storytelling and her pedagogical methods inv

https://www.khm.lu.se/en/sites/khm.lu.se.en/files/cps_poster_2017.pdf - 2026-05-28

BioeconomyStakeholderConference_DK_170515.key Deniz Koca, Ph.D., Lund University, Centre for Environmental and Climate Research BIOECONOMY Graduate Research School deniz.koca@cec.lu.se http://www.cec.lu.se/bioeconomy Advancing the Transition to Bioeconomy: A Systems Approach mailto:deniz.koca@cec.lu.se?subject= http://www.cec.lu.se/bioeconomy Layout Background (What is bioeconomy? Do we all have a

https://www.hallbarhet.lu.se/sites/hallbarhet.lu.se/files/bioeconomystakeholderconference_dk_170515_v2.pdf - 2026-05-28