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Insulin levels at 18–20 gestational weeks in pregnant women with obesity are associated with newborn abdominal fat deposition and DNA methylation in cord blood

We assessed if fasting plasma insulin levels in pregnant women with obesity are associated with newborns’ abdominal fat deposition (dual-energy X-ray absorptiometry) and with cord blood DNA methylation (450k array) in 232 mother–child pairs from the Treatment of Obese Pregnant women (TOP) study. Fasting maternal insulin at 18-20gw was associated with abdominal/total fat mass ratio in newborns inde

Heart failure in Southern Sweden (HISS) : a cross-sectional analysis of primary care patients’ characteristics and physicians’ adherence to guideline-directed medical therapy

Objectives We aimed to describe clinical and diagnostic characteristics of primary care patients with heart failure and physicians’ adherence to guideline-directed medical therapy (GDMT) for treating chronic heart failure. Design Cross-sectional study based on baseline data from the prospective primary care-based study Heart failure in Southern Sweden (HISS). Setting Patients with heart failure we

LIVA23:1

LIVA23:1 LIVA25:1 – Barnlitteraturteori (7,5 hp) vt24 Litteraturlista Fastställd av Sektionsstyrelse 2, Språk- och litteraturcentrum, 5.12.23. FACKLITTERATUR Andersson, Maria och Elina Druker (red.), Barnlitteraturanalyser, Studentlitteratur: Lund 2008 (212 s). Beauvais, Clémentine, The Mighty Child: Time and Power in Children’s Literature, John Benjamins: Amsterdam och Philadelphia 2015, s. 1-11

https://www.sol.lu.se/media/utbildning/dokument/kurser/LIVA25/20241/LIVA25.1.pdf - 2026-05-31

Retinoic Acid regulates hematopoietic development from human pluripotent stem cells.

The functions of retinoic acid (RA), a potent morphogen with crucial roles in embryogenesis including developmental hematopoiesis, have not been thoroughly investigated in the human setting. Using an in vitro model of human hematopoietic development, we evaluated the effects of RA signaling on the development of blood and on generated hematopoietic progenitors. Decreased RA signaling increases the

Social determinants and the role of maternal health care services for equity in maternal health in Ghana from 1988 – 2008

Popular Abstract in Swedish Avhandlingen utgår från förhållandet att mödradödligheten traditionellt varit en tungt vägande faktor för kvinnors totala sjukdomsbörda i låginkomstländer. Mödradödligheten är starkt knuten till såväl allmänna levnadsförhållanden i samhället som till tillgång och kvalitet av professionell hälsovård. Det är därför inte förvånande att mer än 99 av 100 mödradödsfall i värlMaternal health services are the least equitable health care services in most low- and middle-income countries. Improving maternal health in Ghana continues to be a major public health challenge. Socio-economic inequalities within the country are greatly reducing the use of maternal health care services despite government policy reforms to improve access to maternal health care services and interv

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Abstract in Danish I et kursus med 12 studerende i 3 tropiske lande og 36 internationale studerende i Danmark arbejdede de studerende virtuelt sammen i grupper med deltagere i både Danmark og i udlandet. De studerende opnåede samme faglige udbytte som ved tidligere kursusgange med studerende kun i Danmark, men lærte mere om projektsamarbejde per distance og forskellige præsentationsformer. Der var

Total Quality Indicators for the Food Production Chain: is there a need for more labelling?

The state of the farming industry in Europe has been put under the spotlight in recent years due to a number of different food scares and disease outbreaks. Many new quality assurance schemes have been formed to accompany the existing environmental monitoring schemes, to give concerned consumers some guarantee when buying food that it is of a good quality and the environmental load of production h

A presentation of three ab initio atomic structure calculation projects

Three theoretical atomic structure projects of interest for the astrophysical community and the lightning industry which are partially finished will be presented. Extensive ab initio calculations of properties of astrophysical interest has been done or are under its way for Ga I, Ga II, Ga III, In II and In III. The aim of the project is to also make calculations for In I, Tl I, Tl II and Tl III.

miQ - a novel microRNA based diagnostic and prognostic tool for prostate cancer.

Today, the majority of prostate tumours are detected at early stages with uncertain prognosis. Therefore, we set out to identify early predictive markers of prostate cancer with aggressive progression characteristics. We measured the expression of microRNAs (miRNA) using qRT-PCR in FFPE prostatic tissue samples from a Swedish cohort of 49 patients with prostate cancer and 25 without cancer and fou

Lentiviral gene transfer of TCIRG1 into peripheral blood CD34(+) cells restores osteoclast function in infantile malignant osteopetrosis.

Infantile malignant osteopetrosis (IMO) is a rare, lethal, autosomal recessive disorder characterized by non-functional osteoclasts. More than 50% of the patients have mutations in the TCIRG1 gene, encoding for a subunit of the osteoclast proton pump. The aim of this study was to restore the resorptive function of IMO osteoclasts by lentiviral mediated gene transfer of the TCIRG1 cDNA. CD34(+) cel

Dasatinib induces fast and deep responses in newly diagnosed chronic myeloid leukaemia patients in chronic phase: clinical results from a randomised phase-2 study (NordCML006)

We randomised 46 newly diagnosed patients with chronic myeloid leukaemia (median age 56) to receive dasatinib 100mg QD or imatinib 400mg QD and report outcome as an intention-to-treat analysis with 36months follow-up. Early cytogenetic and molecular responses were superior in the dasatinib group, with a tendency that imatinib patients caught up with time. For instance, MR3.0 was reached at 3months

Systematic Analysis of MicroRNAs Targeting the Androgen Receptor in Prostate Cancer Cells.

Androgen receptor (AR) is expressed in all stages of prostate cancer progression, including in castration-resistant tumors. Eliminating AR function continues to represent a focus of therapeutic investigation, but AR regulatory mechanisms remain poorly understood. To systematically characterize mechanisms involving microRNAs (miRNAs), we conducted a gain-of function screen of 1129 miRNA molecules i

HLA-DQB1 genotypes and islet cell autoantibodies against GAD65 and IA-2 in relation to development of diabetes post partum in women with gestational diabetes mellitus.

AIMS: To study HLA-DQB1 genes and islet cell autoantibodies against glutamic acid decarboxylase 65 (GADA) and insulinoma antigen-2 (IA-2A) in relation to diabetes post partum in mothers with diagnosed gestational diabetes mellitus (GDM). METHODS: During 2003-2004, women undergoing a 75g oral glucose tolerance test (OGTT) during pregnancy were invited to participate in the Mamma Study. Cut-off leve

B2B-Marketplace Value Creation, Conceptual Predictions and Empirical Findings

Information technology is a vital driver in today’s business environment. Recent developments of IT have facilitated for the relatively easy creation of markets on the Internet, so called B2B-marketplaces. However, judging from the survival rate of B2B-marketplaces (5 to 10 per cent), it seems like B2B-marketplaces are doing something wrong. This paper scrutinises several theoretical frameworks re