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For universities all over the world, the strategic importance of doctoral education has increased over the last decades. Both locally and internationally we can observe growing activity in three interrelated areas of doctoral education: policy, knowledge formation and practice. Doctoral education is moving and has become a concern for the field of educational development. In a recent Swedish repor

Aims Invariant natural killer T (iNKT) cells, a T cell subset that is CD1d-restricted and expresses a semi-invariant T cell receptor, have been proposed to contribute to dyslipidaemia-driven cardiovascular disease due to their ability to specifically recognize lipid antigens. Studies in mice have attributed pro-atherogenic properties to iNKT cells, but studies in humans investigating associations

North - South collaboration between scientists and collaborators is increasingly prominent and promoted in research. This study examines power dynamics within a North-South research collaboration project conducted between institutions in Tanzania and Germany. The research design is guided by postcolonial considerations of knowledge production and seeks to amplify underrepresented voices from the S

Obesity levels in developing countries are increasing at an alarming rate, while “old” problems such as hunger and undernutrition still persist, creating a paradoxical situation of a double burden of malnutrition. Intertwined with new sustainability challenges such as climate change and land degradation, food, health and sustainability are interconnected in a complex web of relationships, spanning

Background: In most resource poor countries, particularly sub-Saharan Africa, modern contraceptive use and prevalence is unusually low and fertility is very high resulting in rapid population growth and high maternal mortality and morbidity. Current evidence shows slow progress in expanding the use of contraceptives by women of low socioeconomic status and insufficient financial commitment to fami

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Popular Abstract in Swedish Hur upplever och ser personer med blödarsjuka eller sockersjuka sig själva och närstående andra. I den första delen av denna avhandling studeras 27 patienter, 16 till 39 år gamla, med blödarsjuka. Av primärt intresse var från början frågan hur sjukdomen kunde tänkas påverka deras känsloliv och i synnerhet deras syn på sig själva och betydelsefulla medmänniskor. DärutöveThe Affects Towards And Perceptions Of The Self And Significant Others in Hemophiliacs and Diabetics The studies in this dissertation investigated the feelings towards and ways of perceiving the self and significant others in twenty-seven patients with hemophilia between the ages of 16-39 to discern how their perceptual-affect states are organized. Secondly, the relationship between bleeds and aff

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Popular Abstract in Swedish Syfte: Att studera de inter- och intramolekylära processer som sker efter excitation av en porfyrinmolekyl. De huvudsakliga pigmenten i det fotosyntetiska antennsystemet; klorofyll a, klorofyll b, samt bakterioklorofyll a är alla porfyriner, som absorberar solljus och transporterar energin till ett reaktionscenter där energin används för laddningsseparation och elektroThis thesis describes inter and intramolecular dynamics in porphyrin molecules. To create a basis for understanding the energy and electron transfer processes in photosynthesis, the ultrafast dynamics of monomeric chlorophyll a, chlorophyll b and bacteriochlorophyll a were studied with ultrashort laser pulses. The transient absorption spectra of all three molecules were found to have pronounced co

Systemic sclerosis (SSc) is a connective tissue disease with a highly variable prognosis. Since new treatment strategies are emerging, there is a need for prognostic markers in order to help allocate patients to the optimal treatment. When comparison is made to the general population, there is an increased mortality rate in this study, both in the series as a whole and in the subgroups of men and

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Popular Abstract in Swedish Vårt immunförsvar har utvecklats genom evolutionen för att kunna motstå infektioner från diverse mikrober (parasiter, bakterier, virus). Kroppen svarar då med en inflammationsrespons för att kunna bekämpa infektionen. Immunsvaret kan delas upp i det icke specifika immunsvaret, bestående av bl.a. fagocyterande celler samt det specifika immunsvaret, bestående av sk T och The CD4+ T cells have an important role in inflammation. Based on the local cytokine milieu, these cells can differentiate into either a Th1 population promoting cellular immunity or Th2 population involved in humoral immunity. Th2 cells produce the anti-inflammatory cytokines IL-4 and IL-10, which might have a protective role in autoimmune diseases like rheumatoid arthritis (RA) and multiple scle

Popular Abstract in Swedish Akut pankreatit (bukspottkörtelinflammation) drabbar årligen cirka 300 individer per miljon invånare i Sverige. Dödligheten ligger totalt på cirka 4-7 % och betydligt högre, cirka 20 %, vid svår nekrotiserande pankreatit. Mortaliteten är vanligen associerad med multipel organsvikt och korrelerad till storleken på det inflammatoriska svaret. Underliggande mekanismer för Acute pancreatitis (AP) is a common disorder where underlying mechanisms for the local initiating events in the pancreas, the systemic dissemination of the inflammatory response and the remote organ dysfunction still are unclear. The aim of the present study was to further characterize the dynamics and sequence of the immune response in AP, and to determine the cellular origin of the initiating ev