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Aims: This study aimed to investigate the additional value of global longitudinal strain (GLS) on top of left ventricular ejection fraction (LVEF) in long-term risk prediction of combined death and heart failure (HF) re-hospitalization after acute coronary syndrome (ACS). Method and results: This retrospective study included patients admitted with ACS between 2008 and 2014 from the three participa
Background: When a potential stem cell donor to a seriously ill child is a healthy sibling below 18 years, Swedish parents have the legal right and obligation to decide on behalf of the donor child. However, there are potentially conflicting loyalties when parents have one severely ill child in need for a cure and one healthy child who will be subjected to medical procedures. This study explored p
Exposure to diesel exhaust is associated with increased risk of cardiovascular and lung disease. Substituting petroleum diesel with renewable diesel can alter emission properties but the potential health effects remain unclear. This study aimed to explore toxicity and underlying mechanisms of diesel exhaust from renewable fuels. Using proximity extension assay (Olink), 92 proteins linked to inflam
Objects smuggled out of Nazi concentration camps and brought to Sweden by liberated prisoners have been valued museum objects in Sweden for almost 60 years. They and the written testimonies given by survivors represent not only the suffering experienced by the Nazis’ victims and their resistance against dehumanization but also how these aspects of the Second World War and the Holocaust were cultur
Background: The WHO advises against recumbent position for longer periods during labour and birth. It has been suggested that upright posi-tions may improve childbirth outcomes and reduce the need for oxytocin augmentation. However RCTs of interventions to encourage upright positions are scarce. The aims of this study were to assess whether there is a relationship between the use o
Measurements of the fractional momentum loss (Sloss≡δpT/pT) of high-transverse-momentum-identified hadrons in heavy-ion collisions are presented. Using π0 in Au+Au and Cu+Cu collisions at sNN=62.4 and 200 GeV measured by the PHENIX experiment at the Relativistic Heavy Ion Collider and and charged hadrons in Pb+Pb collisions measured by the ALICE experiment at the Large Hadron Collider, we studied
BACKGROUND: In patients with AD, CSF Aβ42 is reduced while Aβ40 remains unchanged. It has been suggested that altered CSF Aβ42 is due to aggregation of this peptide into insoluble plaques, resulting in less soluble Aβ42 available for secretion to the CSF. However, the relations between soluble and insoluble Aβ42 and Aβ40 in the brain and the concentrations of these Aβ peptides in CSF are not well
OBJECTIVE: The purpose was to test the hypothesis that the HLA-DQαβ heterodimer structure is related to the progression of islet autoimmunity from asymptomatic to symptomatic type 1 diabetes (T1D).RESEARCH DESIGN AND METHODS: Next-generation targeted sequencing was used to genotype HLA-DQA1-B1 class II genes in 670 subjects in the Diabetes Prevention Trial-Type 1 (DPT-1). Coding sequences were tra
Two-dimensional polarization imaging (2D POLIM) is an experimental method where correlations between fluorescence excitation- and fluorescence emission-polarization properties are measured. One way to analyze 2D POLIM data is to apply a so-called single funnel approximation (SFA). The SFA allows for quantitative assessment of energy transfer between chromophores with identical spectra [homo-FRET (
Many insects rely on path integration to define direct routes back to their nests. When shuttling hundreds of meters back and forth between a profitable foraging site and a nest, navigational errors accumulate unavoidably in this compass- and odometer-based system. In familiar terrain, terrestrial landmarks can be used to compensate for these errors and safely guide the insect back to its nest wit
Bacteria regulate FtsZ protein levels through transcriptional and translational mechanisms for proper cell division. A cis-antisense RNA, StfZ, produced from the ftsA-ftsZ intergenic region, was proposed to regulate FtsZ level in Escherichia coli. However, its structural identity remained unknown. In this study, we determined the complete sequence of StfZ and identified the isoforms and its promot
Several observables sensitive to the fragmentation of b quarks into b hadrons are measured using 36 fb-1 of s=13 TeV proton-proton collision data collected with the ATLAS detector at the LHC. Jets containing b hadrons are obtained from a sample of dileptonic tt¯ events, and the associated set of charged-particle tracks is separated into those from the primary pp interaction vertex and those from t
OBJECTIVES: To describe clinical characteristics and prognosis related to heart failure (HF) phenotypes in a community-based population by applying a novel algorithm to obtain ejection fractions (EF) from electronic medical records. DESIGN: Retrospective population-based cohort study. SETTING: Data were collected for all patients with HF in Southwest Sweden. The region consists of three acute care
Much of today’s public discourse on crime cases take place on online platforms, as long chains of high-speed posts: speculations, analyses, and laments, as well as ironic, sarcastic, and derogatory comments. These give excellent (and yet risky) possibilities to engage in homemade investigation, with other posters as instant reviewers and audiences. In this article, we explore the interactional ori
In a country with a large historical and current share of emissions, recent climate inaction and political upheaval have disallowed substantial social-environmental reforms from being endorsed. This thesis critically examines the current cycle of contention in the United States by classifying the Sunrise Movement and the Democratic Socialists of America as social movement organizations through the
Migration är en oundviklig och betydande konsekvens av klimatförändringar. Varje år tvingas millioner människor lämna sina hem i kölvattnet av katastrofer och fler väntas migrera i takt med att klimatförändringar ökar i frekvens och magnitud. Det saknas dock rättsliga mekanismer för att gripa an klimatrelaterad migration. Därmed syftar uppsatsen till att kritiskt undersöka i vilken utsträckning prMillions of people are displaced annually due to environmental stress and degradation, causing them to move in prospects of a sustainable livelihood. However, given the lack of mechanisms and systems to provide legal protection for displaced individuals, the future of such migrants is uncertain. Using a human rights-based approach, this thesis critically examines whether the principle of non-refou
This essay will analyze Kazuo Ishiguro’s fantasy (or anti-fantasy) novel The Buried Giant (2016) from an ecocritical approach, with the aspiration to commence an ecocritical dialogue regarding the novel, which, at the time writing this, is non-existent. The first part of the analysis examines the portrayal of nature in The Buried Giant. After that, the text proceeds by looking at intertextual stor
