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Alzheimer's disease (AD) is a common dementia affecting a vast number of individuals and significantly impairing quality of life. Despite extensive research in animal models and numerous promising treatment trials, there is still no curative treatment for AD. Astrocytes, the most common cell type of the central nervous system, have been shown to play a role in the major AD pathologies, including a

In this work, we exploited time-resolved fluorescence polarization anisotropy (TRFA) to characterize un-doped and doped carbon dots (CDs). The rotational correlation time related to the size of the particle through classical Stokes-Einstein-Debye equation. The TRFA technique applied in this study achieves picoseconds time resolution, which approximately corresponds to the particle size determinati

Background: Driving automation systems (DAS), including autonomous driving and advanced driver assistance, are an important safety-critical domain. DAS often incorporate perceptions systems that use machine learning (ML) to analyze the vehicle environment. Aims: We explore new or differing requirements engineering (RE) topics and challenges that practitioners experience in this domain. Method: We

Background Preeclampsia is considered a major cause of maternal and fetal morbidity and mortality. The aim of the present case-control study in Sweden was to assess the hypothesized association between low serum vitamin D concentrations in early pregnancy and the risk of developing preeclampsia since vitamin D may play a role in early placental development. Methods The study included 296 women dia

Popular Abstract in Swedish Små partiklar i form av vätska eller fast material mellan 0.001 till 100 µm i diameter, kan sväva i luften och kallas då aerosolpartiklar. De påverkar direkt på klimatet genom att reflektera solstrålar ut till rymden. Detta gör att vi får ett kallare klimat. Indirekt kan de påverka klimatet genom att verka som kondensationskärnor vid molnbildning. Med detta påverkar de The aim of this work was to study atmospheric aerosols, focusing on the chemical composition, the morphology and the origin of the aerosol in the upper troposphere and lowermost stratosphere. An aerosol sampler was developed for this purpose. A new method for quantitative analysis of the major components of the aerosol, i.e. C, N and O was developed, and methodologies for single-particle analysis

The base (BOP) and the top (TOP) of the world income pyramid represent the poor people and the people from developed countries, respectively. About two-fifths of the world population can be categorized as poor. Poverty is a trap because children born to poor parents are likely to grow up to be poor adults. In recent years, a poverty reduction approach that combines business development with povert

Objective: Developmental programming alters growth and metabolic outcome in children born small for gestational age (SGA). We explored insulin and glucose metabolism in SGA children treated with a fixed GH dose over 1 year. Methods: In the North European Small for Gestational Age Study (NESGAS), 110 short SGA children received GH at 67 mu g/kg/day for 1 year. Insulin secretion was assessed by acut

Mitochondrial abnormalities may be involved in PTSD, although few studies have examined this. Mitochondrial DNA copy number (mtDNAcn) in blood cells is an emerging systemic index of mitochondrial biogenesis and function. The present study assessed mtDNAcn in male combat-exposed veterans with PTSD compared to those without PTSD as well as its correlation with clinical scales.

Autofokus för elektroner Människan har alltid varit intresserad av att studera förlopp som skett så snabbt att de inte gått att observera med blotta ögat. Med hjälp av kameror med korta slutartider kan man frysa ett ögonblick i tiden. Processer i atomer och molekyler sker på en helt annan tidsskala än den vi är vana att fotografera. Atomerna lever i en värld där saker sker så fort att man behöverConclusion The results from the optimization with GA shows that there is no noticeable difference between optimizing for arithmetic and geometric mean of the resolution. The idea behind using the geometric mean is that it would lend smaller importance to outlier values. Both settings found about the same range of values for VBend, VTweak and VExt, with comparable standard deviations. When optimiz

Introduction: Generalised anxiety disorder (GAD) in older adults involves excessive worry and cognitive challenges. Verbal memory impairments is associated to hippocampal dysfunction, with cortisol and brain-derived neurotrophic factor (BDNF) being important in hippocampal integrity. Research on hippocampal volume and verbal memory in older adults with GAD is limited, with mixed findings. This stu

Stor blåklocka bättre pollinerad i staden än på landsbygden Världen över är människor indirekt beroende av pollinerande djur då de förser oss med mat, mediciner och råmaterial genom att hjälpa växters fortplantning. Inom denna djurgrupp dominerar insekter där bin och humlor är särskilt viktiga på nordliga breddgrader. Det finns dock en stor oro kring våra pollinerande insekter idag. Som ett resul

We have studied drug release and skin permeation from several different liquid crystalline lipid formulations that may be used to control the respective release rates. We have studied the release and permeation through human skin of a water-soluble and amphiphilic drug, propranolol hydrochloride, from several formulations prepared with monoolein and phytantriol as permeation enhancers and controll

Popular Abstract in Swedish Denna studie undersöker hur talparagrafen (le paragraphe oral), såsom den definierats av Morel och Danon-Boileau 1998, struktureras och används i L1 franska, i L1 svenska och i L2 franska hos två svenska avancerade inlärare. Den undersökta korpusen består av sju informella och spontana endolingvala och exolingvala samtal. Studien är både kontrastiv och longitudinell i dThis study examines the structure and the use of the speech paragraph (le paragraphe oral), as defined by Morel and Danon-Boileau 1998, in L1 French, in L1 Swedish and in the L2 French production of two advanced Swedish learners. The corpus examined consists of seven informal spontaneous endolingual and exolingual conversations. The study is not only contrastive, but also longitudinal, in the sens

Popular Abstract in Swedish Begreppen ‘participation’ och ‘empowerment’ är flitigt använda inom utvecklingsprojekt i tredje världen. Den betydelse som tillskrivs begreppen idag betonar en normativ tolkning, baserad på ett alternativt perspektiv på utveckling vilket innebär utgångspunkt från de människor utvecklingsprojeket berör snarare än västerländsk kunskap och expertis. Begreppen kräver detaljThe concepts participation and empowerment are frequently used in development projects in the third world. The meaning given to the concepts today signal a normative orientation, marking an alternative, people-centred approach to development. When used in development projects, the concepts demand detailed descriptions. They also demand project implementers, often local NGOs (non-government organis

Investigation of astrophysical plasmas, such as stellar atmospheres, require both knowledge of atomic structure and data. We present laboratory instruments, techniques and tools for acquisition of the data required to derive important atomic parameters such as, wavelengths, oscillator strengths and line profiles. In this thesis new atomic data for advancement of stellar atmosphere analysis are pre

Popular Abstract in Swedish Denna avhandling ger ett bidrag till teorin om strategisäkra kollektiva beslut. I denna teori undersöks under vilka förutsättningar det är möjligt att konstruera omröstningsprocedurer (hädanefter kallade för kollektiva valfunktioner) som är strategisäkra i den bemärkelsen att ingen väljare kan ändra utfallet av en omröstning till sin fördel genom att inte rösta enligt sThis thesis makes a contribution to strategy-proof social choice theory, in which one investigates the conditions under which it is possible to construct social choice functions (i.e., voting procedures) that can never be manipulated in the sense that some voter, by misrepresentation of his true preferences, can change the outcome of a voting and obtain an alternative he prefers to the one that ho

Leukemic cells from 85 children with newly diagnosed precursor B-lineage ALL were tested for in vitro drug sensitivity to a panel of anti-cancer drugs. Minimal residual disease (MRD) was measured by RQ-PCR. There was a significant correlation between MRD day 29 and in vitro sensitivity to prednisolone (p < 0.001) and doxorubicin (p = 0.01 7), drugs administered during induction therapy. In patient

Studien berör användningen av sociala kategorier i polisiär och statlig verksamhet, och visar att social kategorisering leder till en rad problematiska konsekvenser. Efter uppmärksammandet av polisens så kallade Romregister uppstod en debatt om polisens arbetsmetoder och huruvida fördomar förekom inom den polisiära organisationen. Polisiära och statliga insatser som riktar sig mot en särskild grupThis thesis discusses the use of stereotypes and social categories in the police force. The study illustrates how stereotypes inevitably lead to several problematic consequences. Following the uncovering of the so called ”Romani-register”, a debate occurred whether stereotypes existed in the Swedish police force. Targeted police efforts and government initiatives are however a consequence of the c

Litt S13 Kurslitteratur HIS S13 Historia: Kulturhistoria - nätbaserad masterskurs (7,5 p) Fastställd av historiska institutionens styrelse 2011-05-27. Green, Anna (2008). Cultural history. Basingstoke: Palgrave Macmillan. ISBN: 978-0-333- 98675-2. (163 s.) Ehn, Billy & Löfgren, Orvar (2001). Kulturanalyser. 2. omarb. uppl. Malmö: Gleerup. ISBN: 91- 40-63486-8. (180 s.) Kulturhistoriskt tema Varje

https://www.historiska.lu.se/media/utbildning/dokument/kurser/HISS13/20121/Litt_S13.pdf - 2026-05-31