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Popular Abstract in Swedish Idag har patienter med blodcancer (leukemi) eller genetiskt betingade blodsjukdomar (sickelcellanemi etc.) begränsad tillgång till behandlingar som effektivt och riskfritt botar sjukdomstillståndet. Detta arbete inkluderar forskningsresultat ämnade att bidra till utveckling av konceptuellt nya behandlingsmetoder för olika typer av blodsjukdomar. Ett fungerande blodsysteThere is a pressing need for compatible Hematopoietic Stem Cells (HSCs), in high quantities and of good clinical quality, to ensure optimal treatment for patients with various blood malignancies. Pluripotent Stem Cells (PSCs) have the potential to be a source for generating HSCs. The indefinite expansion capacity of PSCs, combined with the possibility of creating these cells from patient-specific

In this work a compact fluorosensor has been built for point-monitoring and imaging applications. The instrument has been applied in fluorescence studies on green vegetation and on malignant tissue. The instrument is based on a violet diode laser, an integrated spectrometer and optical fibers for light delivery and collection of the fluorescence signal. This combination makes the system very compa

Hereditary cystatin C amyloid angiopathy (HCCAA) is a disorder characterised by multiple strokes in young adults, resulting in paralysis and dementia. The disease is caused by a mutation in the gene coding for the peptidase inhibitor cystatin C. The mutation causes an amino acid substitution Leu68 -> Gln in cystatin C (L68Q cystatin C) which results in deposition of the protein in the blood vessel

This paper attempts to address the failings of a predominant paradigm in IS research and practice that emphasises technological determinism. This paradigm makes use of a false belief in the power of rationality in organizational decision-making, and a mythology in which organizational actors can be viewed as passive ‘users’ of technology. We wish to create a discussion of the nature and role of pr

Inom beredskapen mot radiologiska och nukleära olyckor och katastrofer spelar strålningsmätningar en avgörande roll för att ta reda på vad som har hänt och hur farligt det är för människa, djur och natur och på vilket sätt det påverkar miljö och samhällsfunktioner. I Sverige och många andra länder i världen har allmänheten en rättighet att få reda på vad som hänt och vad de utsätts för i ett eventThis thesis describes investigations made on mobile and stationary gammaspectrometry made both under laboratory conditions and in situ. The objective hasbeen to identify and quantify radionuclides in the form of point sources,contamination and widespread deposition in situations where the measurementgeometry is not known beforehand. Both scintillators and semiconductor detectors ofsimilar size wer

In this thesis, I have investigated factors (cues, benefits, and costs) affecting the evolution of an inducible morphological defence in crucian carp (Carassius carassius). Inducible defences are favoured over permanent defences when prey have reliable cues to detect predators, when defences are effective but costly, and when predation pressure is variable and unpredictable, but sometimes s

This paper addresses Test Application Time (TAT)reduction for core-based 3D Stacked ICs (SICs). Applyingtraditional test scheduling methods used for non-stacked chiptesting where the same test schedule is applied both at wafer testand at final test to SICs, leads to unnecessarily high TAT. This isbecause the final test of 3D-SICs includes the testing of all thestacked chips. A key challenge in 3D-

Long-distance migratory animals such as birds and bats have evolved to withstand selection imposed by pathogens across the globe, and pathogen richness is known to be particularly high in tropical regions. Immune genes, so-called Major Histocompatibility Complex (MHC) genes, are highly duplicated in songbirds compared to other vertebrates, and this high MHC diversity has been hypothesised to resul

Health information system (HIS) refers to a data collection and management system that supports the use of health information for planning, management and decision making. Robust HISs are required for the proper management of health data to produce and share high-quality health information for informing planning and decision making at different levels of the health system. This chapter presents th

The aim of the present paper is to explore the interrelated and complex relationships between religionsvetenskap (Religious Studies), religionskunskap (Religious Education) and religionsdidaktik (Religion and Education). After briefly outlining the concurrent developments of Religious Studies as a university discipline and Religion and Eudcation as a non-confessional school subject, both of which

Background: The CTLA-4 blocking antibody ipilimumab has demonstrated substantial and durable effects in patients with melanoma. While CTLA-4 therapy, both as monotherapy and in combination with PD-1 targeting therapies, has great potential in many indications, the toxicities of the current treatment regimens may limit their use. Thus, there is a medical need for new CTLA-4 targeting therapies wit

Introduction: While it is recognized that there are costs associated with postoperative patient follow-up, risk assessments of catastrophic health expenditures (CHEs) due to surgery in sub-Saharan Africa rarely include expenses after discharge. We describe patient-level costs for cesarean section (c-section) and follow-up care up to postoperative day (POD) 30 and evaluate the contribution of follo

Executive functions (EF) decline with age and this decline in older adults with generalised anxiety disorder (GAD) may be influenced by heart rate variability (HRV), brain-derived neurotrophic factor (BDNF), and physical fitness. Understanding these relationships is important for tailored treatments in this population. In this study, 51 adults with GAD (M age = 66.46, SD = 4.08) and 51 healthy con

Zone folded coherent acoustic phonons were generated in a multilayered GaSb/InAs epitaxial heterostructure via rapid heating by femtosecond laser pulses. These phonons were probed by means of ultrafast x-ray diffraction. Phonons both from the fundamental acoustic branch and the first back-folded branch were detected. This represents the first clear evidence for phonon branch folding based directly

Triple-negative breast cancer (TNBC) accounts for 10-20% of primary breast cancers and often has early relapses and aggressive progression. An activated tumour immune response can be prognostic in treatment-naive and chemotherapy-treated TNBC patients and may be assessed using gene expression data. We derived a stand-alone predictor for a proposed immunomodulatory transcriptional TNBC subtype in a

Generalized anxiety disorder (GAD) is a severe and prevalent disorder among older adults. Cognitive behaviour therapy (CBT) is recommended treatment for GAD, but older adults benefit less than younger peers. Physical exercise has been suggested to improve treatment efficacy. We aimed to determine the efficacy of augmenting CBT with physical exercise for older adults with GAD. This randomised contr

Microsoft Word - C V Anders Lindahl sept 2015.doc 1 CURRICULUM VITAE    Surname:  Lindahl                     (530406‐2416)  Christian names: Carl Anders Harald  Date of birth:  6 April 1953  Place of birth: Vetlanda, Sweden  Nationality:  Swedish  Civil status:  Married, 4 children  Address:  Arendala 651, Koängen, 225 92, Lund, Sweden    Exames  BA (Fil.kand) 1978 in the following subjects:  Arc

https://www.geology.lu.se/sites/geology.lu.se/files/c_v_anders_lindahl_sept_2015.pdf - 2026-05-09

22 Utbildningsplan Musikerutbildning arrangering/komposition jazzinriktning, 180 hp – kandidat 1. IDENTIFIKATION Programmets namn och inriktning: musikerutbildning, arrange- ring/komposition jazzinriktning. Omfattning i högskolepoäng: 180. Nivå: Grundnivå (G). Programkod: KGMUS. Inriktning: ARKJ. 2. BESLUTSUPPGIFTER Utbildningsplanen är reviderad och beslutad av konstnärliga fakul- tetsstyrelsen 2

https://www.mhm.lu.se/sites/mhm.lu.se/files/mu_utbildningsplaner_samlingsdokument_arrkompjazz_kand.pdf - 2026-05-09

Microsoft Word - STUDIEPLAN DOKTORSEXAMEN I MUSIK 2010-01-31.doc Postadress: Box 8203, 200 41 Malmö. Besöksadress: Ystadvägen 25. Telefon: 040-325452, Telefax: 040-325480, E-post: Kansli@kansliK.lu.se, Hemsida: http://www.performingarts.lu.se Konstnär l iga faku l te ten i Malmö STUDIEPLAN KONSTNÄRLIG FORSKARUTBILDNING I MUSIK LEDANDE TILL DOKTORSEXAMEN 1. IDENTIFIKATION Programmets namn och inrik

https://www.mhm.lu.se/sites/mhm.lu.se/files/studieplan_doktorsexamen_i_musik_2010-01-31.pdf - 2026-05-09