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Cytogenetic analysis provides important information on the genetic mechanisms of cancer. The Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer (Mitelman DB) is the largest catalog of acquired chromosome aberrations, presently comprising >70 000 cases across multiple cancer types. Although this resource has enabled the identification of chromosome abnormalities leading to speci
Underpinned by Script Theory and the S-O-R model, this research enhances the green tourism consumption literature to identify how destination service quality contributes to visitors’ memorable experiences and loyalty towards a place-based food tourism attraction. A total of 202 tourists who visited the Best of Highlands tea plantation in Malaysia were surveyed using an online questionnaire. Using
OBJECTIVE: To examine whether iron intake and genetically determined iron overload interact in predisposing to the development of childhood islet autoimmunity (IA) and type 1 diabetes (T1D).RESEARCH DESIGN AND METHODS: In The Environmental Determinants of Diabetes in the Young (TEDDY) study, 7,770 genetically high-risk children were followed from birth until the development of IA and progression t
Objective: To study the long-term effect of obesity and bariatric surgery on incidences of osteoarthritis and arthroplasty of hip and knee. Design: Hazard ratios (HR) and incidence rates (IR) of osteoarthritis and arthroplasty of hip and knee were studied in the prospective, controlled, non-randomized Swedish Obese Subjects (SOS) study (bariatric surgery group, n = 2007; matched controls given usu
A meshless collocation method based on radial basis function (RBF) interpolation is presented for the numerical solution of Maxwell's equations. RBFs have attractive properties such as theoretical exponential convergence for increasingly dense node distributions. Although the primary interest resides in the time domain, an eigenvalue solver is used in this paper to investigate convergence properti
To reduce the load on the UAV operator during long-term search and rescue missions, an on-board automatic system is considered that generates control signals for positioning an additional video camera with a narrow field of view. The requirements for the system of automatic detection of the area of interest are defined. Various methods for detecting objects in images are considered, analyzed and c
Over the last few decades, a critical revision of prior scholarship concerning Roman domestic space has led to the reappraisal of the traditional account of the atrium suggesting a possibility for this space to be ‘unroofed’. Accordingly, scholars have proposed to look for a convergence of impulses previously cultivated in isolation combining new theoretical frameworks, and a careful examination o
The traditional approach for measuring myelin-associated water with quantitative magnetic resonance imaging (MRI) uses multi-echo T2 relaxation data to calculate the myelin water fraction (MWF). A fundamentally different approach, abbreviated “mcDESPOT”, uses a more efficient steady-state acquisition to generate an equivalent metric (fM). Although previous studies have demonstrated inherent instab
BackgroundThis study explores expectations for telepresence robots as a tool to reduce absence in education as school absence negatively influences children's academic advancement and psychosocial wellbeing.DesignA qualitative semi-structured interview study.Method and populationUsing convenience sampling, we interviewed 11 children aged 8–17 years with cancer (n = 4), neuromuscular diseases (n =
PURPOSE: The intracorporeal anastomosis (IA) technique possibly results in enhanced recovery and reduced morbidity rates compared to the extracorporeal anastomosis (EA) technique. This study compared the short-term morbidity rates of IA versus EA in segmental resections for colon cancer.METHOD: We performed a retrospective cohort study of consecutive patients from 2015 to 2020 using the IA or EA t
Sustainability scholars increasingly recognize that policy mixes can positively impact socio-technical transitions. However, the temporal dimension of policy interventions remains under-researched, especially in the context of early transition dynamics that typically emerge in niche contexts. In this article, we explore how policy sequencing can play a key role in supporting the scaling-up of earl
Increasing survival rates for childhood cancer have brought attention to the high level of burden of cancer and its treatment. Improving supportive care for children throughout their cancer trajectory is thus important and could reduce the difficulties related to treatment, including time-consuming treatments and the waiting time associated with treatment procedures. The aim of this study is to de
Children's participation in economic activities has been documented as an inseparable part of the family support network in childhood studies. Children as an integral part of the parents' world contribute to enhanced social experiences, the continuity of the societal system, and the holistic well-being of the family. In the pro- baby global south children are political, economic, cultural, and soc
Objective: This study examined the overlap between considering oneself to have stopped nonsuicidal self-injury (NSSI) and the actual cessation of the behavior in terms of days self-injured in the last month and last year, and how these operationalizations are associated with constructs related to NSSI recovery. Methods: A cross-sectional survey including measures of coping, emotion dysregulation,
Background: The aim was to investigate time trends for incidence and long-term net survival in the morphologic subtypes and stages of cervical cancer in Sweden during the period 1960 to 2014. Methods: Women with invasive cervical cancer were identified through the Swedish Cancer Registry. Incidence and net survival were calculated according to morphology, age at diagnosis, and FIGO stage at diagno
Purpose: Image-based analysis of breast tumor growth rate may optimize breast cancer screening and diagnosis by suggesting optimal screening intervals and guide the clinical discussion regarding personalized screening based on tumor aggressiveness. Simulation-based virtual clinical trials (VCTs) can be used to evaluate and optimize medical imaging systems and design clinical trials. This study aim
INTRODUCTION: Since 2005, disease-related human genetic diversity has been intensively characterized using genome-wide association studies (GWAS). Understanding how and by whom this work was performed may yield valuable insights into the generalizability of GWAS discoveries to global populations and how high-impact genetics research can be equitably sustained in the future.MATERIALS AND METHODS: W
