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The present study focuses on fragmented deglycosylated pyranose dehydrogenase (fdgPDH) from Agaricus meleagris recombinantly expressed in Pichia pastoris. Fragmented deglycosylated PDH is formed from the deglycosylated enzyme (dgPDH) when it spontaneously loses a C-terminal fragment when stored in a buffer solution at 4 degrees C. The remaining larger fragment has a molecular weight of similar to
Understanding the role of conformational entropy in protein-ligand interactions remains a major challenge in rational drug design. In this work Galectin-3C (Gal-3C) complexes with glycomimetic macrocyclic ligands FS435 and FS471 were investigated using NMR spectroscopy. The ligands exhibit similar binding free energies, and calorimetric studies revealed significant enthalpy-entropy compensation. S
Title: When the Map Is Wet, Navigation Still Depends on It: Organizational Sensemaking and Digital Infrastructure Dependency Course: BUSN49, Degree Project in Managing People, Knowledge and Change – Master Level Authors: Clara Gerber and Ember Truppelli Supervisor: John Murray Purpose: This study examines how individuals within organizations make sense of digital infrastructure dependency when the
Selective catalytic oxidation (SCO) of ammonia is a interesting field of research and is becoming increasingly more popular due to ammonias role as a hydrogen carrier for ammonia based hydrogen production. With the rise of ammonia based hydrogen, focus now lies on finding cheap and efficient ways to remove unreacted ammonia from the final gas stream. This to be done, without burning or destroying
Companies continuously seek to improve both operational efficiency and financial performance. To support operations and enable investments, capital is required. An important consideration is capital binding, which refers to the amount of capital tied up within the business and the duration for which it remains tied up. While capital binding is often associated with inventory levels, it emerges thr
Offshore wind farms (OWFs) pose a potential threat to migratory birds, either as a barrier or as a result of lethal collisions. We aimed to demonstrate the temporal and spatial frames for potential mitigation measures for a rare and protected species. We analysed 74 autumn migration tracks for 65 GPS-tagged Caspian terns (Hydroprogne caspia) through an area with operating and planned OWFs. On thei
Within the field of Strategic Communication, geopolitical rivalries are increasingly understood as struggles for narratives and discursive dominance. This thesis explores a critical juncture in this landscape: the period between late 2025 and early 2026, marked by US President Donald Trump’s renewed push to acquire Greenland, stating the US would take it “one way or another”. The study examines ho
PUFENDORF INSTITUTE FOR ADVANCED STUDIES http:/www.pi.lu.se FORESTS AND MANKIND the relationship must be made sustainable editors: Gunilla Jönson Thomas Johannesson F O R E ST S A N D M A N K IN D the relation ship m ust be m ade sustain able Aside from the oceans, the world’s forests constitute the most vital element in maintaining a climate which sustains life on Earth. The forests supply all li
https://www.pi.lu.se/sites/pi.lu.se/files/forests_and_mankind_2015.pdf - 2026-07-24
While several scholars do not consider the anointing of (the feet of) Jesus in Bethany described in the Gospel of John to carry any messianic connotations, some claim that a royal messianic notion is behind the anointing. The hypothesis of this paper is that the anointing is indeed to be understood as messianic, but that it is insufficient to consider only one Christological motif to be in the bac
Background & Aims: Non-alcoholic fatty liver disease (NAFLD) has been associated with multiple metabolic abnormalities. By applying a non-targeted metabolomics approach, we aimed at investigating whether serum metabolite profile that associates with NAFLD would differ in its association with NAFLD-related metabolic risk factors. Methods & Results: A total of 233 subjects (mean ± SD: 48.3 ±
As the demand for eco-friendly alternatives to traditional plastics grows, Polyethylene Furanoate (PEF) emerges as a promising solution. Derived from renewable biomass sources, PEF embodies sustainability principles by reducing reliance on finite resources and minimizing environmental impact. PEF is synthesized from 2,5-furandicarboxylic acid (FDCA), a key monomer which upon polymerization has the
1 2018 BECC Gothenburg Ambec, S., & Coria, J. (2018). Policy spillovers in the regulation of multiple pollutants. Journal of Environmental Economics and Management, 87, 114-134. doi:https://doi.org/10.1016/j.jeem.2017.05.011 Andersson-Sköld, Y., Klingberg, J., Gunnarsson, B., Cullinane, K., Gustafsson, I., Hedblom, M., . . . Thorsson, S. (2018). A framework for assessing urban greenery's effects a
https://www.becc.lu.se/sites/becc.lu.se/files/2016-2018_becc_gu_publikationer_0.pdf - 2026-07-24
Insulin stimulates fusion, but not tethering, of GLUT4 vesicles in skeletal muscle of HA-GLUT4-GFP transgenic mice. Am J Physiol Endocrinol Metab 302: E950-E960, 2012. First published January 31, 2012; doi:10.1152/ajpendo.00466.2011.-Insulin regulates glucose uptake into fat and muscle by modulating the subcellular distribution of GLUT4 between the cell surface and intracellular compartments. Howe
Popular Abstract in English Every year globally, an estimated 1.7 million women are diagnosed with breast cancer, while over half a million are killed by this disease. The principal cause of death is metastasis, which is the spreading of the cancer cells from the breast to other vital organs like the brain, liver or lungs, resulting in organ failure and subsequently death. Even though the past decMetastasis is a complex process that remains a major challenge in the clinical management of cancer, because most cancer-related deaths are attributed to disseminated disease rather than the primary tumor. Despite the significant advances in the prediction of prognosis, and therapeutic management of primary breast cancers, coupled with the substantial improvement in our understanding of the molecu
