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The β-glucosidase TnBgl1A catalyses hydrolysis of O-linked terminal β-glycosidic bonds at the nonreducing end of glycosides/oligosaccharides. Enzymes with this specificity have potential in lignocellulose conversion (degrading cellobiose to glucose) and conversion of bioactive flavonoids (modification of glycosylation results in modulation of bioavailability). Previous work has shown TnBgl1A to hy
The recognition of carbohydrates by proteins is a fundamental aspect of communication within and between living cells. Understanding the molecular basis of carbohydrate-protein interactions is a prerequisite for the rational design of synthetic ligands. Here we report the high- to ultrahigh-resolution crystal structures of the carbohydrate recognition domain of galectin-3 (Gal3C) in the ligand-fre
Untitled Sida 1 av 4 Biologiska institutionen Grund- och avancerad utbildning KURSANALYS Datum 2025-06-02 Kursansvarig: Allan Rasmusson Antal studenter: 24 (exkl. omreg.) Antal svar: 19 Omdöme: 3.8/5 Kursanalys: Molekylärbiologi, MOBA03, VT2025 Sammanställd av Allan Rasmusson i samråd med Urban Johanson Sammanfattning av kursvärderingen Mittkursvärdering: Enligt ombuden har kursens första del fung
Kursutvärdering kursnamn Centrum för miljö- och klimatvetenskap Grund- och avancerad utbildning KURSANALYS Datum 2025-05-22 Kursansvarig: Patrik Edén Antal studenter: 44 Antal svar: 10 Betyg (antal G, VG): 15G, 14VG Sida 1 av 2 Sida 2 av 2 Kursanalys: Introduktion till artificella neuronnätverk och djupinlärning (BERN04) höstterminen 2024 Sammanfattning av kursvärderingen Kursutvärdering saknade d
Kursutvärdering kursnamn Sida 1 av 2 Biologiska institutionen Grund- och avancerad utbildning KURSANALYS Datum 251209 Kursansvarig: Christoffer Johansson Antal studenter: 33 Antal svar: 8+2 Betyg: 4,0 Kursanalys: ”Ekologi”, ”BIOC10/12”, VT-24 Sammanfattning av kursvärderingen Studenterna har varit generellt nöjda med kursen (4,0), och med lärarnas insatser (3,8). Kommunikationen har fungerat ok (3
Popular summary Estuarine eutrophication, the systemic limitation of oxygen in a body of water, has been increasingly monitored and scrutinized as an environmental concern needing acute and long term remediation efforts. The roots of eutrophication are largely attributed to anthropic sources within the watershed, sources that are products of modern civilization; such as agricultural and urban poll
Glycerol-3-phosphate dehydrogenase is a biomedically important enzyme that plays a crucial role in lipid biosynthesis. It is activated by a ligand-gated conformational change that is necessary for the enzyme to reach a catalytically competent conformation capable of efficient transition-state stabilization. While the human form (hlGPDH) has been the subject of extensive structural and biochemical
Ribonucleotide reductases (RNRs) catalyze the reduction of ribonucleotides to deoxyribonucleotides, the building blocks for DNA synthesis, and are found in all but a few organisms. RNRs use radical chemistry to catalyze the reduction reaction. Despite RNR having evolved several mechanisms for generation of different kinds of essential radicals across a large evolutionary time frame, this initial r
