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New Findings: What is the central question of this study? Collagen-binding β1-integrins function physiologically in cellular control of dermal interstitial fluid pressure (PIF) in vivo and thereby participate in control of extravascular fluid volume. During anaphylaxis, simulated by injection of compound 48/80, integrin αVβ3 takes over this physiological function. Here we addressed the question wh

Mast cell are found throughout the body, but are especially prominent in tissues that have direct contact with the external milieu such as the skin, gastrointestinal tract and lungs. Mast cells are commonly recognized for their detrimental role in allergic reactions and can, upon activation through the high-affinity receptor for IgE (FcεRI), rapidly produce and secrete many of the mediators respon

Background: Soils contain the largest stock of organic carbon (C) in terrestrial ecosystems and changes in soil C stocks may significantly affect atmospheric CO2. A significant part of soil C is present in cultivated soils that occupy about 35 % of the global land surface. Agricultural intensification has led to practices that may decrease soil organic carbon (SOC), and agricultural management has

Soil gas production processes, mainly anaerobic or aerobic soil respiration, drive major gas fluxes across the soil-atmosphere interface. Carbon dioxide (CO2) effluxes, an efflux which in most ecosystems is a result of both autotrophic and heterotrophic respiration, in particular have received international attention. The importance of both CO2 and methane (CH4) fluxes are emphasised in the Arctic

The Montreal Protocol is working. Concentrations of major ozone-depleting substances in the atmosphere are now decreasing, and the decline in total column amounts seen in the 1980s and 1990s at mid-latitudes has not continued. In polar regions, there is much greater natural variability. Each spring, large ozone holes continue to occur in Antarctica and less severe regions of depleted ozone continu

Human papillomavirus type 16 (HPV16) is a cancer-causing virus that contributes to at least 70% of cervical cancer as well as to other anogenital cancers and head and neck cancer. Understanding HPV16 gene regulation is important to enhance our understanding of HPV16 infections and may contribute to development of antiviral drugs. In this study, we show that nucleosides/nucleoside analogues have th

Klimatförändringarna kommer att påverka ekosystem och samhällen över hela världen. Det är ett problem som kräver drastiska och omedelbara förändringar av vårt sätt att leva och av våra samhällsstrukturer, och därmed politiskt engagemang av aldrig tidigare skådat slag. Under de senaste 30 åren, sedan bildandet av Förenta Nationernas ramkonvention om klimatförändringar (Klimatkonventionen; UNFCCC) åThe rise of climate change as an issue of global concern has rested on scientific representation and understanding of the causes and impacts of, and responses to climatic change. The Intergovernmental Panel on Climate Change (IPCC), in particular, has been central to how climate change has become known as a global political problem. This thesis aims to critically examine the production, negotiatio

Background: The emergence of highly active novel agents has led some to question the role of autologous haematopoietic stem-cell transplantation (HSCT) and subsequent consolidation therapy in newly diagnosed multiple myeloma. We therefore compared autologous HSCT with bortezomib–melphalan–prednisone (VMP) as intensification therapy, and bortezomib–lenalidomide–dexamethasone (VRD) consolidation the

CO2 chemistry has received significant interest in recent time, due to the greenhouse effects of CO2 emissions and the resulting climate change. CO2 reduction reactions, such as methanol synthesis and reverse water-gas shift, is providing a route for recycling of CO2 and thus limiting the CO2 emissions. These reactions are commonly performed over Cu-based catalysts, making the interaction of CO2 a

Boreal forests and peatlands are globally significant carbon stores but they are threatened by rising air temperatures and changes in precipitation regimes and the frequency of natural disturbances. Predicting how the boreal biome will respond to climate change depends on being able to accurately model and upscale the greenhouse gas fluxes between these ecosystems and the atmosphere. This thesis f

Den ökade användningen av artificiell intelligens på e-handelsplattformar på-verkar hur konsumenter interagerar med varumärken i en onlinemiljö. Re-kommendationssystem samlar in information om användaren och presenterar därefter förslag på produkter som den tror användaren kommer finna intres-santa. Utöver en ökad närvaro av artificiell intelligens säljs alltmer förfalskade varor i takt med att onThe increased use of artificial intelligence at e-commerce platforms affects how consumers interacts with trademarks online. Recommendation systems is gathering data from the users and suggests products that it think the user will like. In addition to the increased use of artificial intelligence, the sales of coun-terfeited products are on the rise because of the increased e-commerce. E-commerce p

PII: 0006-8993(81)90498-4 Brain Research, 215 (1981) 147-161 © Elsevier/North-Holland Biomedical Press 147 B E H A V I O U R A L RECOVERY F O L L O W I N G T R A N S P L A N T A T I O N OF SUBSTANTIA N I G R A IN RATS SUBJECTED TO 6-OHDA LESIONS OF THE N I G R O S T R I A T A L PATHWAY. I. U N I L A T E R A L LESIONS STEPHEN B. DUNNETT, ANDERS BJORKLUND, ULF STENEVI and SUSAN D. IVERSEN Department

https://www.wnc.lu.se/sites/wnc.lu.se/files/dunnett_et_al_part_i_brain_res_1981.pdf - 2026-06-12

Sveriges och Europas befolkning blir allt äldre samtidigt som färre föds. Med andra ord ska allt färre yngre människor försörja allt fler äldre. Den 15 december 2008 infördes nya svenska regler för arbetskraftsinvandring från tredjeland. Reformen innebar att det gamla systemet där ansökningar om arbetstillstånd först prövades mot behovet på den inhemska marknaden, den så kallade arbetsmarknadsprövThe Swedish and European population is aging and fewer are born. In other words, fewer young people have to provide for an increasing number of elderly people. On December 15 2008 new Swedish rules for labour migration from third countries were introduced. The old system where an application for work permit was first assessed according to the needs of the domestic market, the so-called ”arbetsmark

Summary: The fieldwork preceding this Master degree thesis took place in Jameson Land, East Greeniand, within the frame of the PONAM (Polar North Atlantic Margins; Late Cenozoic evolution) project. In central Jameson Land, a plateau area at approximately 500 m.a.s.l. forms a marked height in the area around the uppermost reaches of Jyllandselv. Ac. 2 km wide valley, where river ravines are cut dow

Sedan ratificerandet av Europakonventionen om mänskliga rättigheter (EKMR) måste svenska domstolar respektera rätten till domstol vid privata rättsförhållanden och en fair trial enligt artikel 6.1 EKMR, också vid prövningar av ansökningar om civilprocessuella säkerhetsåtgärder. Det huvudsakliga syftet med de civilprocessuella säkerhetsåtgärderna i svensk civilprocessrätt är vidare att de ska komplSince the enactment of the European Convention on Human Rights (ECHR) national courts must consider the right to court in private legal relationships and a fair trial in article 6.1 ECHR, also at hearings of applications for interlocutory injunctions. The object of interlocutory injunctions in Swedish Civil Procedure Law is furthermore to supplement and facilitate the practical litigation, not to

PFAS (per- and polyfluoroalkyl substances) is a large group of pollutants that, over the last decade have been of great academic concern since it has been found all around the globe. PFAS is ubiquitous in our environment and frequently found in low background concentrations in soil and water; recent research has also found that PFAS occur in biotic samples, such as fish and plants. This literature