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In patients admitted alive to hospital after cardiac arrest the most common mode of death is withdrawal of life sustaining therapy due to brain injury. This decicion is preceeed by multimodal neuroprognostication, which includes clinical examination, neurophysiological tests, imagning and serum markers of braininjury. The search for methods to ameliorate the brain injury after cardiac arrest is onIn patients admitted alive to hospital after cardiac arrest the most common mode of death is withdrawal of life sustaining therapy due to brain injury. This decicion is preceeed by multimodal neuroprognostication, which includes clinical examination, neurophysiological tests, imagning and serum markers of braininjury. The search for methods to ameliorate the brain injury after cardiac arrest is on

Eli F. Heckscher found that in 16'th century Sweden: 1) indirect barter was the most common exchange method and 2) monetary exchange was carried out with different coins, none a generally accepted medium of exchange. These findings refute models of the emergence of money, which builds on Jevons and Menger. Heckscher and later Wesley C. Mitchell thought the historical evolution of the exchange syst

Nudging has been discussed in the context of policy and public health, but not so much within healthcare. This scoping review aimed to assess the empirical evidence on how nudging techniques can be used to affect the behavior of healthcare professionals (HCPs) in clinical settings. A systematic database search was conducted for the period January 2010-December 2020 using the PRISMA extension for S

Colon cancer is common in both developed and developing countries, and is responsible for at least 600,000 deaths globally every year. It is therefore the second most common cause of cancer-related mortality. Extensive studies are being conducted worldwide to find more effective drugs that can be used in cancer treatment. In these studies, phytochemicals have proven to be good sources for drug dis

Abstract Background: Osteoarthritis (OA) is the most common joint disorder globally and a major cause of disabiltiy with the knee joint responsible for 80% of the disease burden. Progressive degenerative changes in cartilage tissue result in deterioration and loss of articular cartilage. Cartilage has poor capacity of healing and the detection of degeneration usually occurs at a stage of progressi

Telomeres are special DNA-protein structures that protect ends of chromosomes from being recognized as double-strand breaks. Telomeres consist of tandemly repeated units of TG-rich DNA and associate with telomere-specific proteins.When a cell replicates its chromosomes, a certain piece of DNA is lost from chromosomal ends due to the ´´ end replication problem´´. This progressive shortening of telo

Shale gas extraction commonly known as fracking had support from the UK government with their ‘all out for shale’ policy. Despite this industry has struggled to establish itself mainly due to strong opposition from communities concerned about environmental and health impacts. Most research into the impacts of fracking is concerned with either environmental degradation or physical health impacts wh

Cardiovascular diseases are among the most important causes of death in thedeveloped countries. These diseases are partly caused by too high cholesterolconcentrations in the blood. Avena sativa, oat, is the most common spieces of the genus Avena, and produced in huge amounts worldwide. Oats have been shown to have cholesterol-lowering properties since the 1960s. This property was originally attrib

Background: Botulinum toxin A (BTX-A) has been used to reduce spasticity in children with cerebral palsy (CP) for decades. The purpose of this study was to analyze to what extent BTX-A treatment was used to treat spasticity in a total population of children with CP. We investigated 1) the use of BTX-A in relation to age, sex, and Gross Motor Function Classification System (GMFCS) level, 2) the mos

Streptococcus pyogenes is one of the most common bacteria infecting humans. One of the factors contributing to the disease-causing properties is the secreted streptococcal cysteine proteinase, SpeB, which degrades several host proteins in connective tissue and circulation. SpeB activity depends on the transformation from an inactive precursor, zymogen, into a mature proteinase. We show that

Popular Abstract in English Living organisms are composed of mainly carbohydrate, protein and lipid molecules. Protein molecules are responsible for many biological functions in cells. In order to fulfill their various biological roles, these chain-like molecules must fold into precise three-dimensional shapes. The knowledge of accurate molecular structures is a prerequisite for rational drug desiProtein molecules are responsible for many biological functions in cells. In order to fulfill their various biological roles, these chain-like molecules must fold into precise three-dimensional shapes. The knowledge of accurate molecular structures is a prerequisite for rational drug design and for structure based functional studies. Getting structural information of proteins can be a very difficu

Popular Abstract in English In our current world, the exponential growth in demand for smaller and faster devices leads to the fact that we will eventually face the problem that traditional semiconductor technologies will reach their limitation in terms of size and speed. Humanity's consciousness to tackle the global ecological issues in the next decade, will demand the substitution of all non-reuThe work presented in this thesis addresses the investigation of the electronic, magnetic, and structural properties of late transition metal complexes supported on various surfaces. The research is aimed at studying the interaction between the molecules and the support, together with the intermolecular interaction. This knowledge is essential e.g. for the development of organic molecule-based dev

Forests form the backbone of the European terrestrial carbon sink (State Forest Service & Ministry of Environment, 2018). As the European Union (EU) strives to become climate neutral by 2050, forests are accounted for the natural carbon absorption mechanism (European Commission, n.d.). Currently, the European net land carbon sink is decreasing largely due to forest ageing (Pilli et al., 2022),

Incisional hernia is one of the most common complications (5–20%) after abdominal surgery. Surgery is the only option to cure a hernia. Symptoms of an incisional hernia depend on the size of the abdominal wall defect and the protruding tissue. About 30% of the patients with an incisional hernia will have an operation performed. Traditional surgical sutured techniques have very high recurrence rateIncisional hernia is one of the most common complications (5–20%) after abdominal surgery. Surgery is the only option to cure a hernia. Symptoms of an incisional hernia depend on the size of the abdominal wall defect and the protruding tissue. About 30% of the patients with an incisional hernia will have an operation performed. Traditional surgical sutured techniques have very high recurrence rate

NEW COURSE! Course name: SANN07, Social Anthropology: Engaging with Social Anthropological Theory (Swedish name: Socialantropologi: Fördjupning i socialantropologisk teori). Advanced level master course (Second Cycle). 15 credits. Spring semester. Language of instruction: English. This course is offered as a freestanding course and as a compulsory course within the Master's Programme in Social Ant

Our Solar System is not the only planetary system in the universe. Since the first detected planet orbiting a star other than the Sun, over 4000 exoplanets have been detected. These exoplanets live in systems with an incredible diversity. The systems can include single, giant planets orbiting very close to the star, or they can have multiple planets packed tightly together. What is causing these dThe detections of over 4000 exoplanets as of today has shown that they exist in a wide range of different configurations, otherwise known as architectures. Recently, studies have been made trying to link the environment of host stars to the architectures of their planetary systems and have found that the architectures of planetary systems may not necessarily be uniform in the Milky Way. Since effe

Popular Abstract in English Breast cancer is the most common cancer in women worldwide and the leading cause of cancer-related deaths. Although survival rates are low compared to other cancers, more than 500,000 women worldwide die of breast cancer every year. It is however not a single disease but rather a collection of different diseases with similar appearance but distinct molecular mechanisms.Background: Breast cancer is the most common female malignancy and the leading cause of cancer-related deaths worldwide. Targeted therapy against the main biomarkers estrogen receptor alpha (ER) and human epidermal growth factor receptor 2 (HER2/ERBB2) have greatly improved mortality rates, but ab initio or acquired therapy resistance is common. It is imperative to identify patients who will benef

Popular Abstract in English Wild fruits trees species are widely distributed throughout the African countries. Many of these trees species produce fruits, which are used by the local communities to greater or less degrees. The importance of wild fruits in the diet depends to a large extent on the availability of the fruits, since cultivated fruit trees are not particularly common in the dry regionAbstract Wild fruit trees have significant cultural and socio-economic value in rural areas of Mozambique. Most of the wild fruits are seasonal and are available mainly in the wet season. Generally they have a short shelf-life and are eaten fresh or after minimal processing; the most common method of preservation is sun-drying. The fruits of Adansonia digitata, Landolphia kirkii, Salacia kraussii,

Den första lyckade organtransplantationen var av en njure år 1954, och sedan dess har njurtransplantationer förbättrat livet för de idag över 100 000 patienter globalt som varje år får en ny njure. Mycket av framgångarna är tack vare mediciner som hämmar det adaptiva immunförsvaret, och förhindrar att kroppen attackerar det främmande organet. Den fortsatta utvecklingen av dessa mediciner har lett Kidney transplants are the most common type of organ transplant globally. While immunosuppressants targeting the adaptive immune systems have been successful in improving short-term outcomes, the role of the innate immune system is relatively less studied, and has come under attention as a potential driver of the inflammation causing poor long-term outcomes. In this thesis, sparse statistical meth

Background: Up-to-date estimates of stroke burden and attributable risks and their trends at global, regional, and national levels are essential for evidence-based health care, prevention, and resource allocation planning. We aimed to provide such estimates for the period 1990–2021. Methods: We estimated incidence, prevalence, death, and disability-adjusted life-year (DALY) counts and age-standard