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Acute leukemia, myelodysplastic syndromes (MDS), myeloproliferative neoplasms and lymphomas are the most prevalent diagnoses in adults presenting with new onset cytopenia. Here, we describe two 10-color panels of surface markers (screening and comprehensive panel) applied at the Flow Cytometry Laboratory, University Health Network, Toronto, ON, Canada. A 10-color flow cytometry is applied using th

A total of 45 subfossil reindeer (Rangifer tarandus) antlers and bones - artefacts excluded - have been found over the years in the Baltic countries of Estonia, Latvia and Lithuania. The relatively high number of specimens suggests a stable residence of the species in the eastern Baltic region. For the first time, 12 of these finds were radiocarbon-dated. The ages of the samples range between 1208

PURPOSE: The aim of the present study was to examine changes in the expression of intracellular signal-transduction pathways, specifically mitogen-activated protein kinases, following retinal ischemia-reperfusion. METHODS: Retinal ischemia was induced by elevating the intraocular pressure in porcine eyes, followed by 5, 12, or 20 h of reperfusion. The results were compared to those of the sham- op

Lake Poopó is a terminal lake of the Bolivian Altiplano, with high salinity and heavy anthropogenic pollution from centuries of extensive mining activity. This study aims to describe how the water quality of groundwater and surface water system in different subwater-sheds of the Lake Poopó varies with geology and hydrology. Measurements of total dissolved solids (TDS) in wells show groundwater bec

There are considerable biomass resources in the European Union and mature conversion technologies to exploit the potentials of bioenergy. A challenge confronting the European Union and Member States is how to accelerate the implementation of bioenergy systems and related supply chains. This chapter contributes to the identification, analysis, and discussion of constraints for bioenergy in the Euro

The present study is a philosophical reflection on Martin Buber´s concept, Existential Guilt. To be able to atone existential guilt you must, according to Buber, acknowledge, identify and confess your guilt, if possible, in front of the one you have harmed. The study highlights an area that Buber does not discuss; the area between the existential guilt process and the liberating experiences that B

Aim: To evaluate three types of ventilation systems for operating rooms with respect to air cleanliness [in colony-forming units (cfu/m3)], energy consumption and comfort of working environment (noise and draught) as reported by surgical team members. Methods: Two commonly used ventilation systems, vertical laminar airflow (LAF) and turbulent mixed airflow (TMA), were compared with a newly develop

A search for heavy neutral Higgs bosons and Z′ bosons is performed using a data sample corresponding to an integrated luminosity of 36.1 fb−1 from proton-proton collisions at s=13 TeV recorded by the ATLAS detector at the LHC during 2015 and 2016. The heavy resonance is assumed to decay to τ+τ− with at least one tau lepton decaying to final states with hadrons and a neutrino. The search is perform

Genomic allergen rapid detection (GARD) is an in vitro assay for the prediction of skin sensitizing capacity of chemicals. The GARD assay monitors changes in the expression of 196 genes, termed the GARD prediction signature. In short, MUTZ-3 cells, representing a well-characterized in vitro model of human dendritic cells (DCs), are exposed to the test substances for 24 h. After RNA extraction and