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Free choice of treatment content, support on demand and supervision in internet-delivered CBT for adults with depression : A randomized factorial design trial

Even if much is known regarding the effects of internet-delivered cognitive behaviour therapy (ICBT) for depression there are several topics that have not been studied. In this factorial design trial with 197 participants we investigated if clients in ICBT could select treatment modules themselves based on a selection of 15 tailored treatment modules developed for use in ICBT for depression. We co

The Audience Turn: Crafting Contributions for Impact in Marketing and Consumer Research

This paper introduces an addressability logic for crafting research contributions to advance scientific and societal impact in marketing and consumer research. For research to be meaningful we ask: for whom? Using rhetorical audience analysis, we examine 80 interpretivist articles in four journals over twenty years to identify their intended addressees. We identify four audience categories along aThis paper introduces an addressability logic for crafting research contributions to advance scientific and societal impact in marketing and consumer research. For research to be meaningful we ask: for whom? Using rhetorical audience analysis, we examine 80 interpretivist articles in four journals over twenty years to identify their intended addressees. We identify four audience categories along a

Fatigue trajectories during pediatric ALL therapy are associated with fatigue after treatment: a national longitudinal cohort study

Objective: Fatigue is one of the most prevalent and distressing symptoms reported by survivors of childhood cancer. There is currently a lack of longitudinal studies on cancer-related fatigue, and especially on the relationship between the course of fatigue during treatment and fatigue at follow-up. The purpose of the current study was therefore to investigate if the course of fatigue during treat

Neuropsychological and Neuroanatomical Features of Patients with Behavioral/Dysexecutive Variant Alzheimer's Disease (AD) : A Comparison to Behavioral Variant Frontotemporal Dementia and Amnestic AD Groups

Background: An understudied variant of Alzheimer's disease (AD), the behavioral/dysexecutive variant of AD (bvAD), is associated with progressive personality, behavior, and/or executive dysfunction and frontal atrophy. Objective: This study characterizes the neuropsychological and neuroanatomical features associated with bvAD by comparing it to behavioral variant frontotemporal dementia (bvFTD), a

Transmyringeal ventilation tube insertion for unilateral Menière’s disease : a protocol for a prospective, sham-controlled, double-blinded, randomized, clinical trial

Background: Menière’s disease is an idiopathic disorder characterized by recurrent episodes of vertigo lasting more than 20 min, unilateral sensorineural hearing loss, and tinnitus. If vertigo attacks occur frequently, the patient is usually severely incapacitated. Currently, there is no consensus on the treatment of Menière’s disease. The evidence regarding most treatment options is sparse due to

Whole-body cooling increases plasma endothelin-1 levels in women with primary Raynaud's phenomenon

To understand better the role of endothelin-1 (ET-1) in the pathogenesis of primary Raynaud's phenomenon (PRP), we investigated the basal ET-1 plasma levels and changes after whole-body cooling in healthy women and those with PRP. The study was performed as an open parallel-group comparison during the month of February. The Raynaud group included 21 female patients (mean age 45.3 years, range 21-5

A new dimension to Risk Assessment

Traditional risk assessment frameworks have been focused primarily on the factors of likelihood and impact, utilizing either a numerical (e.g. 1 to 5) or qualitative (e.g.low,medium, high) rating scale, resulting in the traditional two dimensional framework. The challenge of this model is that the focus is too narrow to eectively assess constantly changing risk environments and fails to dierentiat

Generation, Self-assembly, and Characterisation of Medium-entropy Fe0.10Ni0.40Co0.25Pt0.25 Nanoparticles

The ongoing pursuit of advanced multicomponent magnetic nanomaterials with tailored functionalities for applications in data storage, spintronics, and biomedicine necessitates novel synthesis approaches beyond conventional template-based methods. In response, this thesis investigates the generation, self-assembly, and characterisation of largely little-known Fe0.10Ni0.40Co0.25Pt0.25 medium-entropy

Exposure to dioxins and dibenzofurans through the consumption of fish

Background.In some regions, including the Baltic Sea, fatty fish such as salmon and herring contain high levels of polychlorinated dibenzodioxins and dibenzofurans. We investigated human exposure to these potentially toxic substances in relation to the consumption of fish from the Baltic Sea.Methods.Plasma levels of 10 different dibenzofurans and 7 dioxins were analyzed in three groups of Swedish

Ultrasound for the Detection of Gallbladder Malignancy in Primary Sclerosing Cholangitis

Background and Aims: In primary sclerosing cholangitis (PSC), the risk for gallbladder malignancy is increased. Surveillance imaging is used for early diagnosis. The study aims to assess the reliability of ultrasound and magnetic resonance imaging (MRI) for the detection of gallbladder polyps in people with PSC and to define a polyp size as a cut-off at which cholecystectomy is indicated due to th

Multidimensional response mechanism of sulfamethazine migration and antibiotic resistome spread in natural riverbed driven by vertical river water level fluctuations

In order to elucidate the multidimensional response mechanism for migration of antibiotics and spread of resistome in riverbed driven by river water level fluctuations, dynamic reactors were set up to simulate the variation of sulfamethazine vertical migration, biotransformation and resistance genes expression according to fluctuation direction and magnitude. The upward fluctuation of water level

Deposition and 14C-based source apportionment of black carbon in a small lake in southern Sweden since 1450 CE

Black carbon (BC) is produced by incomplete combustion of biomass and fossil fuels and is released as aerosols to the atmosphere with effects on the climate, environment, and human health. Current BC emissions are well monitored in many parts of the world. However, the geographical coverage is limited, and historical records of BC accumulation are still scarce. Here we present a quantification of

An empirical ignition delay correlation allowing cetane number rating in a production compression ignition engine

This work presents an alternative cetane rating method using a production compression ignition (CI) engine, offering an accessible approach for preliminary fuel evaluation without the need for specialized equipment. As part of this work, an empirical correlation was developed linking ignition delay (ID) to both the cetane number (CN) and intake oxygen concentration. The test method follows the pri

Captive bolt guns and suicides: a 15-year Swedish retrospective study

BackgroundThe captive bolt gun is a tool for stunning animals in the meat industry and is not considered a firearm under the Swedish firearm legislation. This study aimed to explore the involvement of such devices in human fatalities, with an emphasis on suicides. Epidemiological characteristics from a longitudinal perspective, as well as risk factors and injury patterns were analyzed.MethodSuicid

Nutritional outcomes and impact of malnutrition in a randomised comparison between standard and prolonged time to surgery after neoadjuvant chemoradiotherapy for oesophageal cancer

Background: Prolonged time to surgery (TTS) after neoadjuvant chemoradiotherapy (nCRT) may enable malnourished oesophageal cancer patients' nutritional status to recover better, possibly improving outcomes with fewer complications and better overall survival (OS) after oesophagectomy. Methods: This is a substudy within a multicentre randomised controlled trial comparing outcomes in patients with o

The order of completing MDP and D12 does not affect the breathlessness responses: A randomised controlled trial

BackgroundBreathlessness is a common and distressing symptom across a wide range of medical conditions. Different aspects (dimensions) of breathlessness can be assessed using the Multidimensional Dyspnoea Profile (MDP) and Dyspnoea-12 (D12) questionnaires. We aimed to examine whether the order of completing MDP and D12 affects the breathlessness responses in people with cardiorespiratory disease.M

Suppressing Halide Segregation Via Dual-Anchoring Strategy for 31.20% Perovskite/Silicon Tandem Solar Cells

The efficiency and stability of wide bandgap (WBG) perovskite solar cells (PSCs) are constrained by photo-induced halide segregation and severe non-radiative recombination, which significantly impedes the advancement of high-efficiency and stable perovskite/silicon tandem solar cells (PSTSCs). In this work, a potassium 4-sulfonic-1,8-naphthalic anhydride salt (4S-NAPS), featuring dual-anchoring si