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We investigated return of spontaneous circulation and of cerebral oxygenation after asphyxia-induced cardiac arrest, using ventilation with air, throughout, or with 100% oxygen for a shorter or longer period. Arterial pressure, heart rate, regional cerebral oxygen saturation (CrSO2) and brain tissue oxygen tension (PbtO2) were measured in one day old piglets that were hypoventilated with air and l

Forskargruppen för systemisk skleros, Lund

Systemisk skleros, SSc, är en ovanlig reumatologisk sjukdom där immunologisk aktivering leder till kärlskada och fibros i hud och inre organ. Hälften av patienterna avlider av komplikationer från hjärta eller lungor, ofta fibros i lungor eller pulmonell arteriell hypertension (PAH). Projekten rör kartläggning av tidiga mekanismer kring patogenes och biomarkörer för tidig diagnos och monitorering aSystemic sclerosis, SSc, is a rare rheumatologic disease where immun activation leads to vascular damage and fibrosis in skin and internal organs. Half of the population will die from complications from heart or lungs, mostly lung fibrosis or pulmonary arterial hypertension (PAH). Our projects aim at early pathogenic mechanisms and biomarkers for early diagnosis and to monitor the disease and the

Translationell Sepsisforskning

Sepsis (när en infektion blir livshotande) är en bortglömd folksjukdom som drabbar lika många som cancer och har högre dödlighet än hjärtinfarkt och är mycket dyrt. Sepsis är ett komplext syndrom och borde precis som cancer inte klassas som en sjukdom utan många olika beroende på vilken bakterie som orsakar infektionen, vilket organ infektionen först drabbar och kanske viktigast av allt i vilket iSepsis (when an infection becomes life threatening) is a neglected public health problem affecting as many as cancer, with a higher mortality rate than myocardial infarction and is very expensive. Sepsis is a complex syndrome, akin cancer and should not be classified as a single disease, rather many different depending on 1. the bacteria causing the infection, 2. Organ focus of the infection, and

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Background and purpose — Fast-track protocols have been introduced worldwide to improve the recovery after total hip arthroplasty (THA). These protocols have reduced the length of hospital stay (LOS), and THA in an outpatient setting is also feasible. However, less is known regarding the first weeks after THA with fast track. We examined patients’ experiences of the first 6 weeks after hospital di