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Introduction: Complicated perianal disease (cPD) may be the sole presentation of Crohn’s disease (CD). The role of small-bowel capsule endoscopy (SBCE) in the diagnostic algorithm of cPD is unclear. We aimed to evaluate the role of SBCE as a diagnostic tool, in patients with cPD, after a negative standard workup for CD. Methods: A multicenter, retrospective, cross-sectional study, in patients with

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Many retail chains believe that the personal service encounter is the solution to declining sales figures. Via a large-scale study of Swedish fashion consumers, we demonstrate, that this may not necessarily be the case. We argue that retailers can potentially save money and convert more customers by providing a more automated journey, which includes self-service technologies, for some customers, a

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IMPORTANCE: Atrial fibrillation (AF), the most prevalent sustained arrhythmia, portends higher risk of cardiovascular morbidity and mortality, and is associated with quantifiable impairment in quality of life. While physical activity is widely recognized for its cardiovascular benefits, recent evidence challenges its role in the development of AF. OBSERVATIONS: Emerging data suggest a U-shaped rel

Andfåddhet och kronisk andningssvikt

Gruppen driver forskning kring mätning och behandling av svår kronisk andnöd (dyspné) samt behandling av kronisk andningssvikt. Gruppen har nära samarbete med ledande forskare nationellt och ett internationellt forskningsnätverk kring klinisk dyspnéforskning. Studier inkluderar epidemiologiska analyser, Cochrane meta-analyser, kliniska kohortstudier samt randomiserade kontrollerade behandlingsstudThe research group focuses on the mechanisms, measurement and treatment of severe chronic breathlessness (dyspnea) and management of chronic respiratory failure. The research is conducted in close collaboration with leading researchers nationally and an international research network. Studies include epidemiological analyses, Cochrane meta-analyses, clinical cohorts and randomized controlled trial

Psykiatrisk epidemiologi och folkhälsa

Enheten för psykiatrisk epidemiologi och folkhälsa studerar ämnesområden som exempelvis psykossjukdomar, suicidologi, beroendetillstånd och neuropsykiatriska tillstånd med klassiska och moderna epidemiologiska metoder. Dessa frågor belyses dels utifrån ett kliniskt perspektiv med traditionella frågeställningar gällande riskfaktorer, utfall, överlevnad och farmakoepidemiologi, dels utifrån ett folkThe Unit for Psychiatric Epidemiology and Public Health studies subject areas such as psychotic disorders, suicidology, substance use disorders, and neuropsychiatric conditions using classical and modern epidemiological methods. These issues are examined both from a clinical perspective, with traditional research questions regarding risk factors, outcomes, survival, and pharmacoepidemiology, and f

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Intracellular delivery of mRNA, DNA, and other large macromolecules into cells plays an essential role in an array of biological research and clinical therapies. However, currentmethods yield a wide variation in the amount of material delivered, as well as limitations on the cell types and cargoes possible. Here, we demonstrate quantitatively controlled delivery into a range of primary cells and c

LU-ATMP: Lunds universitets centrum för avancerade terapier

Sweden's ATMP ecosystem is rapidly expanding, solidifying its place as a key player in Europe. Currently ranking among the top three countries among the EU9 for identified therapeutic ATMP companies, Sweden's strategic investments are further reinforcing its leadership (MSC 2020). This includes ongoing initiatives to establish industrial-scale ATMP manufacturing capabilities, enhancing the country

Människan i rörelse: hälsa och rehabilitering

Forskargruppen bedriver forskning kring förutsättningar och rehabilitering för ett hälsosamt liv där rörelse och aktivitet är i fokus. Forskning som bedrivs i gruppen syftar också till att förbättra förståelsen för påverkan på människans strukturer, funktioner, aktiviteter och delaktighet i omgivande Iiv. Forskagruppens arbete omfattar hela kedjan från hälsopromotion till rehabilitering, genom heResearch within the group concerns conditions and rehabilitation for a healthy life, with a focus on movement and activity. Research within the group also aims to improve understanding of effects on human structure, functions, activities, and participation in society. Research within the group includes the line from health promotion to rehabilitation, throughout the lifespan. Other areas are work-

Psykisk hälsa, aktivitet och delaktighet

Med vår forskning vill vi förstå och främja människors psykiska hälsa, aktivitet och delaktighet och bidra till att människor kan leva ett så meningsfullt liv som möjligt och delta i samhället trots psykisk ohälsa. Att utveckla, utvärdera och implementera återhämtningsinriktade insatser som ger stöd i olika livssituationer och miljöer är därför centralt. Vi vänder oss till olika målgrupper såsomWith our research, we want to understand and promote persons’ mental health, activity and participation and as a result help them to live as meaningful lives as possible and participate in society despite mental ill health. Developing, evaluating and implementing recovery-oriented interventions that help in different life situations and in different environments is therefore critical. We address