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As new therapeutic areas in which genetic material is employed, i.e. gene therapy and DNA vaccination, are expanding, a substantial increase in the demand for gene vectors, e.g. plasmid DNA, is foreseen. Chromatography, being a high-resolution method, is considered essential for the purification of gene vectors when high purity is required. Plasmids are large molecules, which cannot penetrate the
On January 1st, 2006, the Swedish legislation on obtaining DNA reference samples from Suspects and the recording of DNA profiles in databases was changed. As a result the number of samples analysed at the Swedish National Laboratory of Forensic Science (SKL) increased from about 4500 in 2005 to more than 25,000 in 2006. To meet this challenge, SKL launched a flew analysis system to create an unbro
We present a new approach to the minimum-cost integral flow problem for small values of the flow. It reduces the problem to the tests of simple multivariate polynomials over a finite field of characteristic two for non-identity with zero. In effect, we show that a minimum-cost flow of value k in a network with n vertices, a sink and a source, integral edge capacities and positive integral edge cos
Understanding the interaction between surfaces and their surroundings is crucial in many materials-science fields, such as catalysis, corrosion, and thin-film electronics, but existing characterization methods have not been capable of fully determining the structure of surfaces during dynamic processes, such as catalytic reactions, in a reasonable time frame. We demonstrate an x-ray-diffraction-ba
During the last decade, identification of the genes involved in familial forms of Parkinson's disease (PD) has advanced our understanding of the mechanisms underlying the development of different aspects of PD. However the available animal models still remain as the main limiting factor for the development of neuroprotective therapies that can halt the progression of the disease, through which we
Optically controlled one-dimensional photonic crystal structures for the THz range are studied both theoretically and experimentally. A GaAs:Cr layer constitutes a defect in the photonic crystals studied; its photoexcitation by 800 nm optical femtosecond pulses leads to the modulation of the THz beam. Since the THz field can be localized in the photoexcited layer of the photonic crystal, the inter
Object segmentation is the first step towards more advanced robotic behaviors, as robots need to localize objects before attempting tasks such as grasping or manipulation. A robot vision system should be able to provide accurate object hypotheses in reasonably high frame rates, using images and possibly also depth data. This work proposes a fixation-based object segmentation algorithm able to cope
We present a new SAH guided approach to subdividing triangles as the scene is coarsely partitioned into smaller sets of spatiallycoherent triangles. Our triangle split approach is integrated into the partitioning stage of a fast BVH construction algorithm, butmay as well be used as a stand alone pre-split pass. Our algorithm significantly reduces the number of split triangles comparedto previous m
Multi-atlas segmentation has become a frequently used tool for medical image segmentation due to its outstanding performance. A computational bottleneck is that all atlas images need to be registered to a new target image. In this paper, we propose an intermediate representation of the whole atlas set – an überatlas – that can be used to speed up the registration process. The representation consis
In this paper we present a unified formulation for a large class of relative pose problems with radial distortion and varying calibration. For minimal cases, we show that one can eliminate the number of parameters down to one to three. The relative pose can then be expressed using varying calibration constraints on the fundamental matrix, with entries that are polynomial in the parameters. We can
Statistical shape models based on point distribution models are powerful tools for image segmentation or shape analysis. The most challenging part in the generation of point distribution models is the identification of corresponding landmarks among all training shapes. Since in general the true correspondences are unknown, correspondences are frequently established under the hypothesis that correc
A deep understanding of double-directional wireless channels is imperative for wireless system design. This necessitates the development of precise channel models through channel sounding. Given the dynamic nature of wireless channels, a short measurement time is highly desirable. In this paper, we present and validate a dual-polarized millimeter-wave channel sounder that uses a rotating mirror me
Popular Abstract in Swedish Kring familjeproblematiken och för behandlingen av familjekonflikter har det svenska samhället organiserat olika sociala verksamheter som traditionellt regleras av Socialtjänstlagen. Familjerådgivningen är en av dessa verksamheter och definieras som en psykoterapeutisk behandling, till vilken en eller båda parter vänder sig oftast på frivillig basis när de upplever att
