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Study Design. Observational cohort study. Objective. To evaluate by MRI whether a vertebral fracture during childhood is a risk factor for degeneration of adjacent discs. Summary of Background Data. Several studies infer that trauma is a major cause of disc degeneration. Only 1 study has by magnetic resonance imaging (MRI) evaluated disc degeneration in children with a former thoracic or lumbar ve

Polyamines (putrescine, spermidine, and spermine) are essential for growth and survival of all cells. When polyamine biosynthesis is inhibited, there is up-regulation of import. The mammalian polyamine transport system is unknown. We have previously shown that the heparan sulfate (HS) side chains of recycling glypican-1 (Gpc-1) can sequester spermine, that intracellular polyamine depletion increas

Nonsense-mediated mRNA decay (NMD) is a post-transcriptional surveillance process that eliminates mRNAs containing premature termination codons (PTCs). NMD has been hypothesized to impact on several aspects of cellular function; however, its importance in the context of a mammalian organism has not been addressed in detail. Here we use mouse genetics to demonstrate that hematopoietic-specific dele

Background: Galectins are a group of carbohydrate-binding proteins that are involved in neoplastic development and progression. In a previous mass spectrometry-based study, we identified galectin 4 as a down-regulated protein in short-term survivors of pancreatic cancer. This study was performed to validate the prognostic value of galectin 4 in a larger cohort of pancreatic cancer patients undergo

The bone morphogenetic protein (BMP) and Notch signaling pathways are crucial for cellular differentiation. In many cases, the two pathways act similarly; for example, to inhibit myogenic differentiation. It is not known whether this inhibition is caused by distinct mechanisms or by an interplay between Notch and BMP signaling. Here we demonstrate that functional Notch signaling is required for BM

BACKGROUND: Health-promoting interventions tailored to support older persons to remain in their homes, so-called "ageing in place" is important for supporting or improving their health. The health-promoting programme "Elderly Persons in the Risk Zone," (EPRZ) was set up for this purpose and has shown positive results for maintaining independence in activities of daily living for older persons 80 y

PRELIMINÄRT_MVEN15_schema_ht18.xlsx Prel.Schema MVEN015 - Klimatförändringen - vetenskap och samhälle Höstterminen 2018 OBS Alla starttider med kvart utom tentamen! Kurstid: - Kurschef: Niklas Vareman Lärare: GZ Giuliana Zanchi MLL Maj-Lena Linderson JS Johannes Stripple NV Niklas Vareman JAO Johanna Alkan Olsson DHa Dan Hammarlund DH David Harnesk Salar: Litteratur: - Houghton, J. T. 2015: Global

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/preliminart_mven15_schema_ht18.pdf - 2026-06-29

https://www.vetenskaphalsa.se/100-000-bebisar-screenade-for-hog-risk-for-typ-1-diabetes/ - 2026-06-28