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A university student in China today might find himself or herself taking a “golden course” that blends practical and academic training. The student earns degree credit while gaining direct exposure to industry. The course might even be sponsored by Alibaba, the online retail giant, or another large firm.
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Cyclin-dependent kinases (Cdks) control the eukaryotic cell cycle by phosphorylating serine and threonine residues in key regulatory proteins, but some Cdk family members may exert kinase-independent functions that cannot easily be assessed using gene knockout approaches. While Cdk2-deficient mice display near-normal mitotic cell proliferation due to the compensatory activities of Cdk1 and Cdk4, t
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Mitochondrial creatine kinase (Mi-CK) isoenzymes, in contrast to cytosolic CKs, form octameric molecules composed of four stable dimers. Octamers and dimers are interconvertible. Removal of the N-terminal pentapeptide of chicken cardiac Mi-CK (Mib-CK) by limited proteolysis drastically destabilized the octamer. The role of the charged amino acids within the N-terminal heptapeptide was studied in d
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Specialized epitope tags are widely used for detecting, manipulating or purifying proteins, but often their versatility is limited. Here, we introduce the ALFA-tag, a rationally designed epitope tag that serves a remarkably broad spectrum of applications in life sciences while outperforming established tags like the HA-, FLAG®- or myc-tag. The ALFA-tag forms a small and stable α-helix that is func
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Cerebral oedema develops after anoxic brain injury. In two models of asphyxial and asystolic cardiac arrest without resuscitation, we found that oedema develops shortly after anoxia secondary to terminal depolarizations and the abnormal entry of CSF. Oedema severity correlated with the availability of CSF with the age-dependent increase in CSF volume worsening the severity of oedema. Oedema was id
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Thioglycolate-elicited macrophages exhibit abundant conjugation of LC3 with PE (LC3-II). Among other autophagy-related (ATG) proteins, it is proposed that, like in yeast, both ATG5 and ATG7 are essential for LC3 conjugation. Using atg5-deficient (-/-) and atg7-/-macrophages, we provide evidence that loss of ATG5 but not of ATG7 resulted in LC3-II depletion. Accumulation of LC3-II in elicited atg7-
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Mitochondrial fusion and fission are dynamic processes regulated by the cellular microenvironment. Under nutrient starvation conditions, mitochondrial fusion is strengthened for energy conservation. We have previously shown that newborns of Ubl4A-deficient mice were more sensitive to starvation stress with a higher rate of mortality than their wild-type littermates. Ubl4A binds with the actin-rela
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Pancreatic Ductal Adenocarcinoma (PDAC) is a very aggressive disease, lacking effective therapeutic approaches and leaving PDAC patients with a poor prognosis. The life expectancy of PDAC patients has not experienced a significant change in the last few decades with a five-year survival rate of only 8%. To address this unmet need, novel pharmacological targets must be identified for clinical inter
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BACKGROUND: Scintigraphy using technetium-99m labelled dimercaptosuccinic acid ([99mTc]Tc-DMSA), taken up in the proximal tubules, is the standard in functional imaging of the renal cortex. Recent guidelines recommend performing [99mTc]Tc-DMSA scintigraphy with single photon emission computed tomography (SPECT). Prostate-specific membrane antigen (PSMA) targeted positron emission tomography (PET)
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We prove that polynomial calculus (and hence also Nullstellensatz) over any field requires linear degree to refute that sparse random regular graphs, as well as sparse Erdős-Rényi random graphs, are 3-colourable.
Mven03 planering ht18 180829
MILJÖVETENSKAP Preliminär planering/schema 180829 Kurs: MVEN03 - Miljövetenskap: Analys och metodik, 15 hp HT 2018 Kursansvarig: Nina Reistad NR nina.reistad@fysik.lth.se Lärare: Estelle Larsson EL estelle.larsson@med.lu.se Christian Lindh CL christian.lindh@med.lu.se Per Erik Isberg PEI per-erik.isberg@stat.lu.se Pål Axel Olsson PAO pal_axel.olsson@biol.lu.se Martijn van Praagh MVP martijn.van_pr
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/mven03_planering_ht18_180829.pdf - 2026-07-01
Mven03 planering ht18 180830
MILJÖVETENSKAP Preliminär planering/schema 180830 Kurs: MVEN03 - Miljövetenskap: Analys och metodik, 15 hp HT 2018 Kursansvarig: Nina Reistad NR nina.reistad@fysik.lth.se Lärare: Estelle Larsson EL estelle.larsson@med.lu.se Christian Lindh CL christian.lindh@med.lu.se Per Erik Isberg PEI per-erik.isberg@stat.lu.se Pål Axel Olsson PAO pal_axel.olsson@biol.lu.se Martijn van Praagh MVP martijn.van_pr
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/mven03_planering_ht18_180830.pdf - 2026-07-01
Mven03 planering ht18 180831
MILJÖVETENSKAP Planering/schema 180831 Kurs: MVEN03 - Miljövetenskap: Analys och metodik, 15 hp HT 2018 Kursansvarig: Nina Reistad NR nina.reistad@fysik.lth.se Lärare: Estelle Larsson EL estelle.larsson@med.lu.se Christian Lindh CL christian.lindh@med.lu.se Per Erik Isberg PEI per-erik.isberg@stat.lu.se Pål Axel Olsson PAO pal_axel.olsson@biol.lu.se Martijn van Praagh MVP martijn.van_praagh@mv.lu.
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/mven03_planering_ht18_180831.pdf - 2026-07-01
Äldre får inte tillräcklig smärtlindring – Vetenskap och Hälsa
Äldre får inte tillräcklig smärtlindring – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Äldre får inte tillräcklig smärtlindring 2016-05-31 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Bara hälften av de äldre män som lider av smärta
https://www.vetenskaphalsa.se/aldre-far-inte-tillracklig-smartlindring/ - 2026-06-29
Risk för blodpropp vid autoimmuna sjukdomar – Vetenskap och Hälsa
Risk för blodpropp vid autoimmuna sjukdomar – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Risk för blodpropp vid autoimmuna sjukdomar 2011-11-28 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Foto: Colourbox I en nationsövergripande
https://www.vetenskaphalsa.se/risk-for-blodpropp-vid-autoimmuna-sjukdomar/ - 2026-06-30
