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Digital PCR techniques are ideally suited for accurately quantifying trace amounts of target DNA sequences, such as tumor-derived mutant DNA that is present in the blood circulation of patients with cancer. Here, we describe an approach marrying low-coverage whole-genome sequencing of tumor tissues, to enumerate chromosomal rearrangement breakpoints, together with droplet digital PCR (ddPCR)-based

“Commensuration” as an analytic framework for studying the expanding measuring culture in social work Teres Hjärpe, PhD, Lund University, School of Social Work, teres.hjarpe@soch.lu.se. My PhD-project in social work deals with measurements and statistics as knowledge base and source for governance of social work activities. Social workers are currently experiencing the measuring and ranking of the

The compactness of mobile terminals complicates the design of multiple antennas, since coupling among the antennas increases when they are placed in proximity of one another. While it is possible to mitigate coupling between closely spaced antennas, a tradeoff in bandwidth is required. In this paper, we highlight ground plane excitation as an additional dimension to consider in the design of multi

Functional monomers play a key role in preparing molecularly imprinted polymers (MIPs) by forming complex with templates to create recognition sites in the polymers. In this paper, a new strategy was proposed to design functional monomers for efficient MIPs synthesis. This strategy dated from the investigations on previously developed MIPs. In propranolol imprinting process, methacrylic acid has a

The polymerase chain reaction (PCR) is the backbone of contemporary DNA/RNA analysis, ideally enabling detection of one or just a few target molecules. However, when analysing food or forensic samples the analytical procedure is often challenged by low amounts of poor quality template molecules and complex matrices. Applying optimised and validated methods in all steps of the analysis workflow, i.

During the last few years, a more liberal use of premedication in children scheduled for Ürinary tract examinations was noted. In this retrospective study, the influence of the institution of psychological means for preparation as supplement or alternative to premedication on the incidence of cases receiving premedication was investigated. During the period from 1978 to 1982, this was followed in

The main goal with this thesis is to develop a method to maximize the fuel efficiency [ton/l] in construction machines, while fulfilling the desired productivity [ton/h]. This is achieved by focusing on two of the main influencers; the machine concept evaluation and the development of operator assist systems. To be able to perform a concept evaluation that is unbiased from control engineering expe

The focus of this work is detecting pedestrians, captured in a surveillance setting, and locating them in world coordinates. Commonly adopted search strategies operate in the image plane to address the object detection problem with machine learning, for example using scale-space pyramid with the sliding windows methodology or object proposals. In contrast, here a new search space is presented, whi

In this work, we synthesized a series of nanoparticle-supported boronic acid polymer brushes for affinity separation of glycoproteins. Polymer brushes were prepared by surface-initiated atom transfer radical polymerization of glycidyl methacrylate and N-isopropylacrylamide, followed by stepwise modification of the pendant as well as the end functional groups to introduce boronic acid moieties thro

BACKGROUND: There is a lack of published, validated questionnaires for evaluating psychosocial morbidity in patients with breast hypertrophy undergoing breast reduction surgery.AIM: To validate the breast evaluation questionnaire (BEQ), originally developed for the assessment of breast augmentation patients, for the assessment of psychosocial morbidity in patients with breast hypertrophy undergoin

From an environmental perspective, a separate collection and recycling system for post-consumer discards could contribute to improved environmental protection as well as economic benefits. This paper investigates the environmental potential of a business model proposed in Sweden in order to improve the utilization of plastic shopping bags. The business model aims to reduce the consumption of plast

The article engages in a critical discussion of the related variety/regional branching argument and foregrounds a more differentiated perspective on regional industrial path development. It contributes by (i) sharpening the definition of key concepts, namely specialisation and diversity, related and unrelated variety; (ii) discussing their relevance in local and nonlocal spaces; (iii) scrutinizing

We report on the design and performance of a velocity map imaging (VMI) spectrometer optimized for experiments using high-intensity extreme ultraviolet (XUV) sources such as laser-driven high-order harmonic generation (HHG) sources and free-electron lasers (FELs). Typically exhibiting low repetition rates and high single-shot count rates, such experiments do not easily lend themselves to coinciden

We demonstrate a velocimetric technique based on femtosecond laser-induced cyano (CN) chemiluminescence (FLICC). High intensity emission originated from CN(B-X) fluorescence was observed in filaments generated by focusing a femtosecond laser in methane-seeded nitrogen gas flows. The emission is strong and can last for hundreds of microseconds with a proper methane concentration. FLICC was adopted

Domain decomposition based time integrators allow the usage of parallel and distributed hardware, making them well-suited for the temporal discretization of parabolic systems. In this study, a rigours convergence analysis is given for such integrators without assuming any restrictive regularity on the solutions or the domains. The analysis is conducted by first deriving a new variational framework

Aromatic polymers functionalised with cycloaliphatic quaternary ammonium (QA) cations are currently emerging as base stable anion exchange membranes (AEMs) for use in alkaline fuel cells and water electrolyzers. In the present work we have first prepared poly(biphenyl piperidine)s in superacid-mediated polycondensations, and then introduced different N-spirocyclic QA cations via cyclo-quaternisati

In this article, I outline the foundations of a consistent and systematic approach to conceptualizing communities in action-oriented sustainability research. More specifically, I develop a conceptual heuristic based on key questions related to ontology, epistemology, methodology and motivation that should be useful for researchers regarding the process of initiating, clarifying and reporting on re