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Minimal Contribution of Fasting Hyperglycemia to the Incidence of Type 2 Diabetes in Subjects With Normal 2-h Plasma Glucose

OBJECTIVE - To assess the relative contribution of increased fasting and postload plasma glucose concentrations to the incidence of type 2 diabetes in subjects with a normal 2-h plasma glucose concentration. RESEARCH DESIGN AND METHODS - A total of 3,450 subjects with 2-h plasma glucose concentration < 140 mg/dl at baseline were followed up in the San Antonio Heart Study (SAHS) and the Botnia Stud

Cerebral inflammation is an underlying mechanism of early death in Alzheimer's disease: a 13-year cause-specific multivariate mortality study.

Introduction: Although Alzheimer’s disease (AD) is associated with early death, its life expectancy differs greatly between patients. A better understanding of this heterogeneity may reveal important disease mechanisms underlying the malignancy of AD. The aim of this study was to examine the relation between AD pathologies and early death in AD caused by dementia. Methods: At a memory clinic, 247

Proactive identification of work and situational factors that can affect safety in air traffic control.

In an organization where the safety level is high and incidents and serious accidents are very rare, a steady erosion of safety awareness and protective measures can occur, especially when productive demands rise. Thus, it is important to continuously identify and monitor aspects in the organization that can affect work performance and safety. In an ongoing joint research project between the LFV G

Places of Dying and Rituals of Mourning

The purpose of this paper is to explore in what way the place becomes important for those who are affected by disasters or sudden death. According to human geography people have affective bonds to the concrete physical places where they are living and moving in their everyday live. Places are also constructed as meeting places where people create social relations. In the discotheque fire in Gothen

Sugar intake and cardiovascular disease risk: With an emphasis on genetic and metabolomic biomarkers of sugar intake

Introduction: Contrary to popular belief, there is limited research on sugar intake as a risk factor for cardiovascular disease. While the links between sugar-sweetened beverage intake and cardiovascular disease risk are well-established, little is known about the associations for overall added or free sugar intake and other dietary sources of added sugar. Objective markers of habitual sugar intak

Lactoferrin-derived peptide PXL01 impacts nerve regeneration after sciatic nerve reconstruction in healthy and diabetic rats

INTRODUCTION: Although advanced surgical techniques are available, satisfactory functional outcomes after peripheral nerve injuries are uncommon. Hence, immune-modulating factors such as PXL01, a lactoferrin-derived peptide that improves axonal outgrowth in injured human digital nerves, have gained attention. We previously reported a short-term immunosuppressive effect of PXL01 after the repair of

Prospective Assessment of Clinically Relevant Fluid Balance Thresholds Associated With Postoperative Complications in Advanced Ovarian Cancer

Background: Reliable data on optimal fluid management in the perioperative period for patients with advanced ovarian cancer undergoing cytoreductive surgery is limited. These patients often present with malignant ascites and are prone to significant fluid shifts perioperatively. For this reason, our objective was to define clinical targets for optimal fluid balance and determine whether initial as

The EAT-Lancet diet in relation nutrient intake among older adults : insights from the Gothenburg H70 birth cohort study

Background: The EAT-Lancet Commission has proposed a global reference diet aimed at promoting both human health and environmental sustainability. While adherence to this dietary pattern has been associated with reduced risks of chronic disease and lower environmental impact, concerns remain about its ability to meet nutritional requirements - particularly among older adults. The aim was to explore

Mini-review of the EAT-Lancet planetary health diet and its role in cardiometabolic disease prevention

Human diets play a crucial role in both human health and environmental sustainability. In 2019, the EAT-Lancet Commission on healthy diets from sustainable food systems introduced the EAT-Lancet planetary health diet, a universal reference diet designed to promote human health while minimizing environmental degradation. It is a predominantly plant-based dietary pattern, rich in whole grains, veget

Adherence to the EAT-Lancet reference diet and risk of type 2 diabetes, metabolic dysfunction-associated steatotic liver disease, and their co-occurrence

Background and aims: The EAT-Lancet Commission proposed a healthy dietary pattern to prevent diet-related diseases while promoting planetary sustainability, but little is known regarding its associations with type 2 diabetes (T2D) and metabolic dysfunction-associated steatotic liver disease (MASLD), both of which are highly prevalent and frequently co-exist. We aimed to assess association of this

Protection Against Pneumonia Induced by Vaccination with Fimbriae Subunits from Klebsiella pneumoniae

Background: Klebsiella pneumoniae infections pose a great burden worldwide, causing high morbidity and mortality, which are worsened by the increase in multidrug-resistant strains. New therapeutic/prophylactic strategies are urgently needed to overcome antibiotic resistance and reduce the health and economic impacts of diseases caused by this pathogen. Fimbriae are important virulence factors invo

Health surveillance for South African Para athletes: an 88-week prospective study in a resource-limited setting

Objectives Longitudinal health monitoring studies including Para athletes are lacking in low- and middle-income countries (LMICs). This study aimed to introduce a surveillance programme developed for Swedish Para athletes to high-level South African Para athletes and describe their self-reported health outcomes.Design Using a prospective cohort design, we distributed weekly electronic surveys to P

Associated factors, triggers and long-term outcome in Complex Regional Pain Syndrome (CRPS) in the upper limb - A descriptive cross-sectional study

The pathophysiology behind Complex Regional Pain Syndrome (CRPS) is not fully understood and associated factors and triggers for developing the condition are debated. We aimed to study such factors and long-term outcome in a descriptive cross-sectional study with a well-defined population with CRPS in the upper limb and related to sex and CRPS type. In retrospectively collected data from medical r

Solution and Interfacial Properties of Cyclic Containing Anionic Surfactants

The bulk micellar and surface adsorption behaviour of a bio-derived cyclic-containing anionic surfactant, sodium tetradecyl furan sulfonate (STFS), has been studied in this work. To determine its viability as an alternative to petrochemically derived surfactants in detergents, the self-assembly andadsorption properties were measured both alone and in binary and ternary mixtures with a common anion

Prognostic performance of preoperative cardiac troponin and perioperative changes in cardiac troponin for the prediction of major adverse cardiac events and mortality in noncardiac surgery : A systematic review and meta-analysis

Background Increased postoperative cardiac troponin (cTn) independently predicts short-term mortality. Previous studies suggest that preoperative cTn also predicts major adverse cardiovascular events (MACE) and mortality after noncardiac surgery. The value of preoperative and perioperative changes in cTn as a prognostic tool for adverse outcomes has been sparsely investigated. Methods and findings

Latent Space Score-based Diffusion Model for Probabilistic Multivariate Time Series Imputation

Accurate imputation is essential for the reliability and success of downstream tasks. Recently, diffusion models have attracted great attention in this field. However, these models neglect the latent distribution in a lower-dimensional space derived from the observed data, which limits the generative capacity of the diffusion model. Additionally, dealing with the original missing data without labe

Musik i rörelse - En intervjustudie om hur svensk folkmusik- och dans kan berika rytmikmetoden

I denna C-uppsats undersöker jag hur svensk folkmusik- och dans kan berika rytmikmetoden. Rytmikmetoden är mitt huvudämne och utgångspunkten för studien och uppsatsen innehåller därför en historisk översikt över rytmikmetodens utveckling från grundaren Jaques-Dalcroze till idag. Jag förklarar även grundläggande principer, metod och innehåll i rytmikmetoden för att göra jämförelsen med undervisningTitle: Music in motion- An interview study on how Swedish folk music and dance can enrich the method of Eurythmics. In this essay I examine how Swedish folk music and dance can enrich the Eurythmics method. Eurythmics is the starting point for the study and the paper contains a historical overview of Eurythmics, the development from the founder Jaques-Dalcroze to the teaching method of Eurytmics i