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We aimed to estimate stratified absolute (cumulative) and relative (standardized incidence ratios; SIRs) risks of non-Hodgkin lymphoma (NHL) in relatives of NHL patients. A cohort of 169 830 first-degree relatives of 45 406 NHL patients who were diagnosed between 1955 and 2010 in five European countries was followed for cancer incidence. The lifetime (0-79 year) cumulative risk of NHL in siblings

AIMS/HYPOTHESIS: Type 2 diabetes is a chronic metabolic disorder associated with devastating microvascular complications. Genome-wide association studies have identified more than 60 genetic variants associated with type 2 diabetes and/or glucose and insulin traits, but their role in the progression of diabetes is not established. The aim of this study was to explore whether these variants were al

Purpose: To assess performance of a biomarker-based score that predicts the five-year risk of diabetes (Diabetes Risk Score, DRS) in an independent cohort that included 15-year follow-up. Method: DRS was developed on the Inter99 cohort, and validated on the Botnia cohort. Performance was benchmarked against other risk-assessment tools comparing calibration, time to event analysis, and net reclassi

BACKGROUND: Stroke is common in cancer patients, but risk estimates for different cancer sites/types have not been determined. The aim of this nationwide study was to examine whether there is an association between cancer and first hospitalisation for haemorrhagic or ischaemic stroke. METHODS: All 820,491 individuals in Sweden with a diagnosis of cancer between 1st January 1987 and 31st December 2

Moraxella catarrhalis is an emerging human respiratory pathogen in patients with chronic obstructive pulmonary disease (COPD) and in children with acute otitis media. The specific secretion machinery known as outer membrane vesicles (OMVs) is a mechanism by which Gram-negative pathogens interact with host cells during infection. We identified 57 proteins in M. catarrhalis OMVs using a proteomics a

This article presents a protocol for assessing team performance in terms of control based on cognitive systems engineering theory. The protocol changes the focus of team performance assessment from good and bad behaviours towards team activity. By using Hollnagel’s contextual control model (COCOM), a protocol is developed so that team activity can be described as four control modes. Data is collec

There are ethnic differences in the incidence of venous thromboembolism. This is the first nationwide study to examine whether there is an association between country of birth in first-generation immigrants and first hospitalisation for venous thrombosis (VT) and pulmonary embolism (PE), and to study whether a similar association exists in second-generation immigrants.

The incidences of both type 1 diabetes (T1D) and T2D are increasing worldwide. T2D is associated with many cancers. However, no data are available on cancer of unknown primary (CUP), a relatively common, fatal cancer for which tobacco smoking is the only known risk factor. At diagnosis, CUP metastases are found in various organs, which has implications for prognosis. We carried out a nationwide st

Reseavdraget – Motverkar det politiska spelet incitament som kan förbättra miljön? Reseavdraget, att vara berättigad till att dra av en del av kostnaderna som uppkommer till följd av resor till och från arbetsplatsen på skatten, har förundrat mig under flera år. Är reseavdraget rättvist utformat, belönar det ett samhällsekonomiskt olönsamt val eller kan det skapa incitament för arbetspendlare attIncome Tax-deduction for commuting expenses has been criticised and discussed for a long time without having reached any conclusions or reformations. Critical opinions in the debate are that a reformation would disfavour taxpayers living in the countryside with no options except car commuting and decreasing size of labour market regions. At the same time tax evasion is a huge problem because taxpa

Vägar slits konstant och kräver konstant förbättringar och ombyggnationer. För att möjliggöra detta krävs personer som befinner sig ute på vägarna. Tekniken har gått framåt inom området trafiksäkerhet men skulle behöva förbättras ytterligare om vägarbetare ska vara säkra på sin arbetsplats. Även trafiken har förändrats över åren. Idag finns fler fordon på vägarna än aldrig förr. Bilarna är säkrareRoads are constantly worn down and demands improvements and reconstructions. To make this possible there has to be road workers on the road. Road safety has been improved along the years but can still be improved more. Today there are more vehicles on the road than ever before. The cars are more safe and therefore is encouraging to higher speeds as they are driven together with all safety features

Inom marknadsföring är det en ständig kamp att framställa varumärken som det bästa där det är vanligt att locka med diverse gåvor och belöningar för att försöka få lojala kunder. Syftet med studien var att undersöka om en belöning (choklad) kunde påverka studenters attityd gentemot designen på olika reklambilder. Närmare bestämt om attityden kunde påverkas av belöningen men också om det skiljer siWithin marketing there is a constant struggle to promote brands as the best and it is common practice to promise various gifts and rewards in an attempt to attract loyal customers. The purpose of the study was to investigate whether a reward (chocolate) could influence students' attitudes towards different ads. Specifically, if the attitude could be influenced by the reward but also if it diff

This thesis is a discourse theoretical analysis of the European Unions foreign- and security policy. I use a discourse theoretical method inspired by Ernesto Laclau and Chantal Mouffe and use their concepts of nodal points, elements, moments and chains of equivalence. In my analysis I draw upon theories in relation to different kinds of power in international relations and especially in relation t

Det förekommer kommersiella standardavtal och konsumentstandardavtal. Införlivandet av standardvillkor saknar lagstiftning i både hänseenden. Högsta domstolens avgöranden är därför den primära rättskällan för utvecklingen. Konsumentavtal omfattas däremot av tvingande lagstiftning som har till syfte att skydda konsumenter från oskäliga avtalsvillkor. Standardavtalsrätten är central utgångspunkt förThere are commercial standard contracts and consumer standard agreements. The incorporation of standard terms lacks legislation in both respects. The ruling of the Supreme Court is therefore the primary source of law for development. Consumer contracts, on the other hand, are covered by mandatory legislation whose purpose is to protect consumers from unfair contract terms. The standard contract la

Video Sharing Websites constitute a rather peculiar situation. On one hand, they are considered as part of what the Commission perceives as online sharing economy: users are eligible to derive income from monetizing their audiovisual content. On the other hand, their business model is reminiscent of what is described as “free -economy”: access to the audiovisual content is prima facie provided wit

Gaming as a Service is not defined in existing research. The lack of a formal definition leads to an ambiguity between its function as a business model and the long-term strategy of the firm. The purpose and aim of this study is to investigate the definition of GaaS business model, distinguishing its function from the strategy. Furthermore, the key components of the model are established based on

Recent years has seen a growth of so-called ”Al-Qaeda franchises”, terrorist groups who formally ally with Al-Qaeda. This study investigates the phenomenon through how one such actor, the “Salafist Group for Preaching and Combat” (GSPC), has developed after its alliance with Al-Qaeda in 2006 and rebranding as ”Al-Qaeda in the Islamic Maghreb” (AQIM). By analyzing GSPC before and after the alliance

Sustainable development requires a change of values, norms, and capabilities within individuals and societies, and education is a crucial means to achieve these goals. However, transformation is not a simple task as dominant structures due to path-dependency and lock-in processes resist change, put pressure on innovative approaches, and hinder their potential for change. Thus the question is how s

So, what does a new life for the old fire station mean? It means that it is possible for a new generation to utilize the Gåsebäck landmark and historical building. The building should be attractive for the investors, for the city, and its inhabitants. The provided opportunities for the development of the building could be considered as a temporary solution for maintaining the history of the Gåsebä

In Swedish, adverbials mainly occur in two positions in the clause: postverbally (last in the clause) or medially (before the finite verb in subordinate clauses and after the finite verb but before e.g. infinite verbs in main clauses). VP adverbials are said to have their natural position postverbally, but they can also be placed medially. This thesis examines factors that influence the placement