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Gaussian Mixture Model (GMM)-based vector quantization of Line Spectral Frequencies (LSFs) has gained wide acceptance in speech coding. In predictive coding of LSFs, the GMM approach utilizing Kalman filtering principles to account for quantization noise has been shown to perform better than a baseline GMM Recursive Coder approaches for both clean and packet loss conditions at roughly the same com

In this study, a fully three-dimensional calculation method has been further developed to simulate and analyze various processes in a thick anode duct. The composite duct consists of a porous layer, the flow duct and solid current connector. The analysis takes the electrochemical reactions into account. Momentum and heat transport together with gas species equations have been solved by coupled sou

E-business is becoming more and more common today. The predictions of future growth give clear indications that companies will use e-business more and more. However in the growth of e-business it has been identified that there is a common lack of understanding in customer needs and logistics. In order to reduce some of this non-understanding this thesis seeks answers to the following question: - H

Popular Abstract in Swedish Allt eftersom fler och fler organismers totala uppsättning gener, genomet, sekvenseras ökar fokus på att kartlägga de genprodukter, proteiner, som uttrycks. Att kunna studera de proteiner som uttrycks mer eller mindre vid olika tidpunkter eller cellulära tillstånd utgör en viktig del i sökandet efter kunskap om biologiska och medicinska processer. Studier av den totala The study of the protein complement of a genome is called proteomics. Proteomics can be defined as identification, quantification and characterization of a total set of proteins expressed at different time-points or under different cellular states to provide global information about biological processes. The study of membrane proteins is a challenging area in the development of proteomic research.

In this paper, we compare two approaches to numerically approximate the solution of second-order Gurtin–Pipkin type of integro-differential equations. Both methods are based on a high-order Discontinous Galerkin approximation in space and the numerical inverse Laplace transform. In the first approach, we use functional calculus and the inverse Laplace transform to represent the solution. The spect

This paper is concerned with the estimation of macroscopic properties such as the permittivity or the thermal conductivity of a composite material from the microstructure. A new method of estimating the microstructural parameters, such as the volume fraction of anisotropic two-phase composite material, is derived. The parameters are estimated using information from measurements of the random mater

One great advantage of optical hyperspectral remote sensing from unmanned aerial systems (UAS) compared to satellite missions is the possibility to fly and collect data below clouds. The most typical scenario is flying below intermittent clouds and under turbulent conditions, which causes tilting of the platform. This study aims to advance hyperspectral imaging from UAS in most weather conditions

A theatre performance with and about 4 war veterans with PTSD. In an autobiographical tur de force they take us back to their life changing moments and try to recreate the lives they had before they got crashed by war. Produced by Fix&Foxy together with Betty Nansen Teatret.TURNÉFORESTILLING.

Risk scores play an important role in clinical medicine. With advances in information technology and availability of electronic healthcare record, scoring systems of less commonly seen diseases and population can be developed. The aim of the article is to provide a tutorial on how to develop and validate risk scores based on a virtual dataset by using R software. The dataset we generated including

The ionizable-lipid component of RNA-containing nanoparticles controls the pH-dependent behavior necessary for an efficient delivery of the cargo - the so-called endosomal escape. However, it is still an empirical exercise to identify optimally performing lipids. Here, we study two well-known ionizable lipids, DLin-MC3-DMA and DLin-DMA using a combination of experiments, multiscale computer simula

Open science aims to improve research accessibility, replicability, and consequently its quality. Empirical software engineering entails both data and artifacts, which may be shared more or less openly, to support transparency. However, the trade-offs involved in balancing the openness against integrity and secrecy concerns need methodological guidance. Aim. We aim to derive such advice, based on

Osteoarthritis (OA) is a degenerative disease that affects the synovial joints, especially the knee joint, diminishing the ability of patients to perform daily physical activities. Unfortunately, there is no cure for this nearly irreversible musculoskeletal disorder. Nowadays, many researchers aim for in silico‐based methods to simulate personalized risks for the onset and progression of OA and ev

Crater-forming events are generally followed by the development of hydrothermal systems due to the rapid heating of the target rock. Such hydrothermal systems are a feature of nearly all large terrestrial impact structures. For the Siljan impact structure in Sweden, there is evidence for such a fossil hydrothermal system, possibly triggered by the impact event ca. 380 Ma. To investigate the therma

Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To determine the effects of higher versus standard doses of caffeine on mortality and major neurodevelopmental disability in preterm infants with (or at risk of) apnea, and preterm infants peri-extubation. To determine the effects of early versus late discontinuation of caffeine administration on m

Background: The 2017 Alzheimer’s disease (AD) Strategic Biomarker Roadmap (SBR) structured the validation of AD diagnostic biomarkers into 5 phases, systematically assessing analytical validity (Phases 1–2), clinical validity (Phases 3–4), and clinical utility (Phase 5) through primary and secondary Aims. This framework allows to map knowledge gaps and research priorities, accelerating the route t

Background: To reduce local recurrence risk, rectal washout (RW) is integrated in the total mesorectal excision (TME) technique when performing anterior resection (AR) for rectal cancer. Although RW is considered a safe practice, data on the complication risk are scarce. Our aim was to examine the association between RW and 30-day postoperative complications after AR for rectal cancer. Methods: Pa