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In the present study, a simple and reliable antioxidant screening technique based on lactate dehydrogenase (LDH) oxidation by Cu2+-mediated Fenton's reaction has successfully been developed. Oxidation of LDH by hydroxyl radical consequently leads to enzymatic inactivation, while addition of antioxidants can protect and regain enzyme activity. This method demonstrated a high feasibility on detectin
Using classical design optimization methods for implant-bone studies does not completely guarantee a safety and satisfactory performance, due in part to the randomness of bone properties and loading. Here, the material properties of the different bone layers are considered as uncertain parameters. So their corresponding yield stress values will not be deterministic, that leads to integrate variabl
Drug repurposing or re-profiling has become an effective strategy to identify novel indications for already-approved drugs. In this study, peptidomimetic FDA-approved HIV/HCV inhibitors were explored for their potential to be repurposed for the inhibition of the replication of dengue (DENV) and chikungunya virus (CHIKV) by targeting the NS2B-NS3 and NSP2 protease, respectively. MM/GBSA-based bindi
The functional significance of fibrin deposits typically seen in inflammatory lesions, carcinomas and in healing wounds is not fully understood. In the present study, we demonstrate that fibrinogen/fibrin specifically bound to native Col I (collagen type I) and used the Col I fibre network as a base to provide a functional interface matrix that connects cells to the Col I fibres through alpha V be
Objectives: To investigate the safety of a novel percutaneous circulatory support device during high-risk percutaneous coronary intervention (PCI). Background: The Reitan catheter pump (RCP) consists of a catheter-mounted pump-head with a foldable propeller and surrounding cage. Positioned in the descending aorta the pump creates a pressure gradient, reducing afterload and enhancing organ perfusio
Background: Negative pressure wound therapy (NPWT) has remarkable effects on the healing of poststernotomy mediastinitis. Foam is presently the material of choice for NPWT in this indication. There is now increasing interest in using gauze, as this has proven successful in the treatment of peripheral wounds. It is important to determine the effects of NPWT using gauze on heart pumping function bef
Abstract Aim: The aim of the thesis was to evaluate the use of advanced MRI technology to improve results of epilepsy surgery, with focus on language and memory functions. Methods: In paper I, 25 patients with drug-resistant epilepsy were retrospectively included in the study for having been referred to high resolution 3T MRI with and without surface coils. The surface coils were placed over the s
Searches for pair-produced scalar leptoquarks are performed using 20 fb[Formula: see text] of proton-proton collision data provided by the LHC and recorded by the ATLAS detector at [Formula: see text] TeV. Events with two electrons (muons) and two or more jets in the final state are used to search for first (second)-generation leptoquarks. The results from two previously published ATLAS analyses a
This bachelor thesis investigates how investments in new sets of transportation infrastructures could affect regional development. By using central theories for transportation geography and regional development, empirical comparison and interviews with experts within the field and politicians, this paper answer four different research questions to discuss the purpose of the thesis. The questions a
Populationen av 65 år och äldre har ökat i Sverige, vilket kan resultera i ett växande behov av arbetsterapeutiska åtgärder. Syftet med studien är att undersöka pensionärers upplevelse av aktivitetsbalans och aktiviteters värde för hälsa och välmående; samt vilka hinder och förutsättningar som förekommer. En kvalitativ ansats valdes och åtta pensionärer från Skåne intervjuades genom semistrukturer
På grund av den snabba förändringen i det audiovisuella medielandskapet får konsumenterna och särskilt minderåriga alltmer tillgång till medieinnehåll via andra digitala plattformar än traditionella TV och video on demand tjänster. Av den anledningen är det idag mer lönsamt för företag att annonsera genom produktplacering och sponsring på plattformar för videodelning som inte regleras inom ramen fDue to the rapidly changing pace of the audiovisual media landscape, consumers and especially minors are increasingly accessing media content via other digital platforms than traditional television and on-demand services. For that reason, is it today more profitable for companies to advertise through product placement and sponsorship on video-sharing platforms which are not regulated within the sc
Världen står inför stora ekonomiska, sociala och miljömässiga utmaningar, vilket kräver en ökad innovationstakt och en acceleration av omställningen till en hållbar utveckling. Samhället förändras i en snabb takt och omställning kräver nya och starka samarbeten mellan industri och samhälle. För att arbeta mer effektivt och framgångsrikt med att uppnå FN:s 17 globala hållbarhetsmål har Sverige skap
Striving to contribute to research on child- and youth spirituality and African theology with a contextually grounded, non-western, qualitative youth perspective, the aim of this study is to seek an understanding of the spirituality of male youth that live on the streets in Nairobi. To fulfil this aim, the research task carried out is an analysis of the source material from six focus group intervi
The master thesis seeks to develop a control system for the Crazyflie 2.0 unmanned aerial vehicle to enable aggressive and autonomous flight. For this purpose, different rigid-body models are considered, differing primarily in their parametrisation of rotation. The property of differential flatness is explored and several means of parametrising trajectories in at output space are implemented. A ne
Titel: Blockkedjeteknologins relevans för svensk hälso- och sjukvård: En omfattande utvärdering av hur teknologins möjligheter och vårdens framtidsvision överlappar Författare: Svante Nyman och Mattias Wendler Handledare: Carl-Johan Asplund, Avdelningen för Produktionsekonomi, LTH & Sarah Lidé, Branschspecialist Hälso- och sjukvård, PwC Sverige Bakgrund: Idag är vården i Sverige i många Title: The Importance of Blockchain Technology for Swedish Healthcare: An Evaluation of the Opportunities of Blockchain and the Future of Healthcare Authors: Svante Nyman and Mattias Wendler Supervisors: Carl-Johan Asplund, Faculty of Engineering, Lund University & Sarah Lidé, Healthcare Industry Expert, PwC Sweden Background: Today, healthcare in Sweden is, in many cases, costly, but th
