Search results

Popular Abstract in Swedish Kroppens immunförsvar brukar delas in i det medfödda och det adaptiva immunförsvaret. Det medfödda immunförsvaret reagerar snabbt på yttre hot såsom bakterier. Olika sorters vita blodkroppar är väldigt viktiga för detta snabba svar på infektion och i min avhandling har jag koncentrerat mig på en av dessa; neutrofilen. Neutrofilen är den vita blodkropp som först koNeutrophil elastase (NE) has important roles in innate immunity, killing pathogens and controlling the immune response; but how NE is targeted to developing granules is not understood. Therefore, the aim of this thesis was to investigate the sorting of NE. Transfection experiments in a leukemic cell line, which were confirmed in normal hematopoietic cells, showed that a population of proNE was ta

Prostacyclin is the major arachidonic acid metabolite of the vascular endothelium and is produced mainly via the cyclooxygenase-2 pathway. By acting on the prostacyclin (IP) receptor on platelets and vascular smooth muscle cells, prostacyclin exerts vasodilatory and antiaggregative/antiadhesive effects. Previous studies have shown that prostacyclin production increases after brain trauma, but the

Background. In SBRT of lung tumours no established relationship between dose-volume parameters and the incidence of lung toxicity is found. The aim of this study is to compare the LQ model and the universal survival curve (USC) to calculate biologically equivalent doses in SBRT to see if this will improve knowledge on this relationship. Material and methods. Toxicity data on radiation pneumonitis

Affärssystem ses som en organisations nervsystem då det integrerar verksamhetens alla avdelningar och processer. Att byta affärssystem är en komplex förändring vilket gör det relevant att ha vetskap om vilka drivkrafter som ligger till grund för systembytet. Syftet med studien är att bidra till ökad förståelse för på vilka grunder organisationer väljer att implementera nya affärssystem. Studiens f

The aim of this study was to examine and illuminate how people who are born deaf experience their encounters with administrative authorities. The study was based on qualitative interviews. Several themes were identified in the interviews: knowledge, deaf competence, accessibility, communication, interpreter usage, audism and discrimination. The analysis was based on the notions of accessibility, s

Invasive alien species are organisms that have been introduced to an area outside their natural distribution range and threatens animals, habitats or humans in the new area. The raccoon (Procyon lotor) is a mesopredator originating from North and Central America that has been introduced in Europe and Asia. Since the first European introductions of raccoons in Germany, natural dispersal and pet tra

The purpose of this research is to investigate Generation Y and Generation Z and their relation and approach to influence marketing and what challenges these generations’ preferences and behaviors could generate for managers within lifestyle brands. The research question this study is aiming to analyze is: What role do generational differences play in influence marketing and what are the potential

Hjärntumörer utgör cirka 2,5% av alla cancerdiagnoser i Sverige (2013) och femårsöverlevnaden är cirka 50%. Hjärntumörer diagnostiseras med bildtagningstekniker såsom datortomografi (CT), positronemissionstomografi (PET) och magnetkamera (MR). En MR-bild byggs upp av signaler från protoner i vatten, som är en av människokroppens vanligaste beståndsdelar. För att möjliggöra diagnostisering och klas

Sverigedemokraternas diskurs om HBTQ-rättigheter har länge varit omtalad. De har generellt setts som homofientliga i media och av andra politiker. 2019 verkar däremot en förändring ha skett då de presenterar nya, möjligtvis mer HBTQ-vänliga, förslag. I den här studien undersöks och analyseras Sverigedemokraternas diskurs i HBTQ-frågor från 1989 till 2019. Syftet med studien är att klargöra vad de

Radikalisering har i Sverige, liksom övriga världen, debatterats på olika politiska nivåer. För flertalet har idag begreppet blivit synonymt med IS-anhängare. Sverige står inför ett högaktuellt dilemma; när nu IS-områden tycks vara på väg mot en upplösning. Flertalet av de svenska anhängarna återvänder och hur ska då Sverigehantera situationen; såväl juridiskt som moraliskt. De mänskliga rättighet

It has been shown that the semi-arid environment of the Sahelian belt plays an important role in the global carbon uptake as the fluctuation of its primary productivity can be determinant for the global carbon uptake. The insect Schistocerca gregaria commonly known as the desert locust is a disturbance factor that can affect the vegetation productivity for consecutive seasons. In this study the de

The movement and distribution of ecologically important herbivores such as elephants are of great significance to conservation biologist seeking to understand the fundamental triggers that influence their mobility and the extent to which these parameters affect how they utilize their immediate and surrounding resources. The recent advancement in animal tracking technology coupled with the availabi

Population ageing affects most European countries, placing increasing pressure on publicly funded Long Term Care (LTC) systems. Informal care is often seen as a low-cost alternative to formal care services, yet it may induce unwelcome reductions in labour supply. This study presents evidence on the relationship of informal care provision, employment probability, and work hours of mature caregivers

Seasonal hydrological forecasts of future streamflow volumes can provide water resources managers with valuable information to improve long-term water resources planning and water use efficiency. The latest generation of coupled ocean-atmosphere general circulation models provides an opportunity for the prediction of hydroclimatic variables (e.g. precipitation, streamflow; soil moisture) at long l

The beneficial effects of HLA matching at the HLA-A, -B and -DR loci on recipient short- and long-term survival in heart transplants have been established in a number of studies. The objective of the present study was to evaluate the importance of individual HLA alleles at the HLA-A, -B and -DR loci as risk factors for recipient death within one year after transplant by using artificial neural net

Transgender persons experience a disproportionate representation in adverse mental health conditions globally. In Sweden there are tangible efforts to improving mental healthcare overall, but as a minority population, transgender persons still struggle with meeting their mental healthcare needs. While social factors such as stigma and discrimination act as catalysts for this burden, there is an ab

There are many actors included in the humanitarian system, such as NGOs, UN humanitarian agencies and governments. However, a gap in the humanitarian system can be identified where the traditional actors lack resources, which provides an opportunity for the private sector to be more involved, particularly in preparing for humanitarian operations. Therefore, in this research, a multiple-case study