Filetype
Context: Rapid growth has been suggested to promote islet autoimmunity and progression to type 1 diabetes (T1D). Childhood growth has not been analyzed separately from the infant growth period in most previous studies, but it may have distinct features due to differences between the stages of development. Objective: We aimed to analyze the association of childhood growth with development of islet
BACKGROUND: Lichens, which represent symbiotic associations of fungi and algae, are potential sources of numerous natural products. Physciosporin (PHY) is a potent secondary metabolite found in lichens and was recently reported to inhibit the motility of lung cancer cells via novel mechanisms.PURPOSE: The present study investigated the anticancer potential of PHY on colorectal cancer (CRC) cells.M
Harvesting whole-tree biomass for biofuel combustion intensifies removal of nutrients from the ecosystem. This can be partly abated by applying ash from the combustion back to the system, as the ash is rich in nutrients. Ash is very alkaline and ash application raises soil pH, which in turn can stimulate microbial activity and thus decomposition and mineralization. Our aim was to test if ash induc
Climate change and its associated challenges may have an impact on people and communities. Studies provide conceptual and empirical insight of the relationship between social capital and resilience. However, the social dimensions of resilience have received little attention in climate change research. This short article provides a rapid review of published studies that investigate the social dimen
The WHO/UNICEF Joint Monitoring Program (JMP) for Water Supply, Sanitation and Hygiene (WASH) produces global estimates of the real situation of access to water, sanitation and hygiene services, and sanitation and hygiene in households, educational institutes and health care facilities; however it is lacking data on schools in Kazakhstan. Thus, the aim of this research was to assess access to WASH
Aims The aim of this study was to investigate the incidence, risk factors, and outcome of venous thromboembolism (VTE) following anterior cruciate ligament (ACL) reconstruction in a nationwide cohort. Patients and Methods All ACL reconstructions, primary and revision, that were recorded in the Swedish Knee Ligament Register (SKLR) between 2006 and 2013 were linked with data from the Swedish Nation
Background and purpose: To determine the prevalence of vertebral hemangiomas (VHs), establish a new classification of VHs based on their MRI-signal pattern, and study their natural history. Methods: MRI of 1000 consecutive patients who underwent at least two MRI with an interval of at least 3 years. Growth rate and change of MRI-signal pattern during the follow-up period were the parameters includ
Hybridization can result in novel allelic combinations which can impact the hybrid phenotype through changes in gene expression. While misexpression in F1 hybrids is well documented, how gene expression evolves in stabilized hybrid taxa remains an open question. As gene expression evolves in a stabilizing manner, break-up of co-evolved cis- and trans-regulatory elements could lead to transgressive
Polypharmacy increases the risk of drug-drug interactions that may disturb treatment effects. The aim of this study was to investigate the frequency of codispensing of potentially interacting or contraindicated drugs related to PH-specific treatment in the Swedish pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) population. All prescribed drugs, on an
Background: An understudied variant of Alzheimer's disease (AD), the behavioral/dysexecutive variant of AD (bvAD), is associated with progressive personality, behavior, and/or executive dysfunction and frontal atrophy. Objective: This study characterizes the neuropsychological and neuroanatomical features associated with bvAD by comparing it to behavioral variant frontotemporal dementia (bvFTD), a
Objective: Fatigue is one of the most prevalent and distressing symptoms reported by survivors of childhood cancer. There is currently a lack of longitudinal studies on cancer-related fatigue, and especially on the relationship between the course of fatigue during treatment and fatigue at follow-up. The purpose of the current study was therefore to investigate if the course of fatigue during treat
An accurate estimation of evapotranspiration (ET) is vital for understanding the global hydrological cycle. However, large uncertainties in the present global ET products originate from the distinct model structures, assumptions, and inputs. The maximum entropy production (MEP) model provides a novel method for modeling ET based on parsimonious inputs and energy conservation. In this study, an R p
BACKGROUND: Global perceptions of barriers to women in orthopaedics have not been assessed. The purpose of this study was to determine the importance of international barriers to women entering and advancing within orthopaedic surgery.METHODS: An anonymous, online survey was distributed to women medical students, trainees, and practicing surgeons via Women in Orthopaedics Worldwide, the "Women in
BACKGROUND: [Corrected] Clinical assessment is not always sufficient to predict postoperative (PO) cardiac complications. B-type natriuretic peptide (BNP) has an important prognostic value in patients with heart failure. Its value as a predictor of events in orthopedic surgeries has not yet been tested.OBJECTIVE: To assess the value of BNP in predicting cardiac complications in the PO period of or
Conspiracies regarding vaccines are widely prevalent, with negative consequences on health-seeking behaviors. The current study aimed to investigate the possible association between the embrace of vaccine conspiracies and the attitude to booster COVID-19, seasonal influenza, and monkeypox (mpox) vaccinations as well as the perceived side effects following COVID-19 vaccination. The target populatio
Paleo-proxy data indicate that a “Green Sahara” thrived in northern Africa during the early- to mid-Holocene (MH; 11 000 to 5000 years before present), characterized by more vegetation cover and reduced dust emissions. Utilizing a state-of-the-art atmospheric chemical transport model, TM5-MP, we assessed the changes in biogenic volatile organic compound (BVOC) emissions, dust emissions and seconda
Wind-abraded cobbles (ventifacts) and aeolian sand are known from the sandy-gravelly coastal areas of south-western Sweden, especially in association with raised deltas. Ventifacts are recorded on at least two different stratigraphic levels, at some sites atop glaciofluvial sediment, at other sites atop littoral deposits, and in some places at both levels, while aeolian sand usually forms a surficWind-abraded cobbles (ventifacts) and aeolian sand are known from the sandy-gravelly coastal areas of south-western Sweden, especially in association with raised deltas. Ventifacts are recorded on at least two different stratigraphic levels, at some sites atop glaciofluvial sediment, at other sites atop littoral deposits, and in some places at both levels, while aeolian sand usually forms a surfic
BackgroundPrevious studies have suggested that Toxoplasma gondii (T. gondii) infection might be associated with fatty liver disease. However, the relationship between non-alcoholic fatty liver disease (NAFLD) and T. gondii infection has not been investigated in a large population. We aimed to study the relationship between those two diseases using a population-based dataset from the United States.
BACKGROUND: Blood loss and adult blood transfusions are common during the neonatal period in preterm infants. The objective of the study was to clarify if degree of loss of fetal haemoglobin (HbF) was associated with later retinopathy of prematurity (ROP).METHODS: Retrospective observational cohort study. In total, 452 infants born <30 gestational weeks at a tertiary level neonatal intensive care
Background The prognostic value of blood lactate as a predictor of adverse outcome in the acutely ill patient is unclear. The aim of this study was to investigate if a peripheral venous lactate measurement, taken at admission, is associated with in-hospital mortality in acutely ill patients with all diagnosis. Furthermore, we wanted to investigate if the test improves a triage model in terms of pr
