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High grade serous ovarian cancer (HGSOC) is accompanied by an immune-rich but heterogenous tumor microenvironment. Although tumor associated tertiary lymphoid structures (TLS) are linked to favourable antitumor immunity, B cells may also adopt spatial distribution patterns favourable for immune suppression. This study evaluated whether the abundance and spatial distribution patterns of CD20+ B cel

Background/aims: During the last decade, improved neonatal care has resulted in increased survival of the most immature infants and improved health of more mature infants. We hypothesise that this has affected incidence and treatment of retinopathy of prematurity (ROP), enabling guidelines for screening to be modified. Methods: In Sweden, all infants with gestational age (GA) at birth ≤30 weeks ar

Objective: Steady state insulin-like growth factor-1 (IGF-1) levels vary significantly during continuous intravenous infusion of recombinant human insulin-like growth factor-1/recombinant human insulin-like growth factor binding protein-3 (rhIGF-1/rhIGFBP-3) in the first weeks of life in extremely preterm infants. We evaluated interleukin-6 (IL-6) and insulin-like growth factor binding protein-1 (

Aim: Clinical seizures are common after cardiac arrest and predictive of a poor neurological outcome. Seizures may be myoclonic, tonic-clonic or a combination of seizure types. This study reports the incidence and prognostic significance of clinical seizures in the target temperature management (TTM) after cardiac arrest trial. Our hypotheses were that seizures are associated with a poor prognosis

This article analyses the history of the Swedish welfare state, with a special emphasis on the development of Swedish family policy between 1930 and 1975. It is argued that a coalition between state officials and state-appointed experts was active in the shaping and legitimising of the concept of family as well of family politics. The underlying assumption of the paper is that the concepts of the

The now Swedish province of Scania has had a long history of violence and unrest, with several wars being fought on Scanian soil. Such tumultuous times must have impacted the common people and their living conditions, yet bioarchaeological research is lacking for post-medieval Scania and much of Sweden. By analysing a skeletal material from a 16-18th century semi-urban cemetery in Ängelholm, for w

The aim of this study was to elicit reference data representative of normal findings at transvaginal gray-scale and Doppler ultrasound examination of the uterus and ovaries in postmenopausal women. A total of 144 asymptomatic postmenopausal women with normal findings at clinical gynecological examination were included in the study. They underwent transvaginal sonography including Doppler measureme

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BACKGROUND: Anal sphincter rupture is a serious complication of vaginal delivery and almost half the affected women have persistent defecatory symptoms despite adequate primary repair. During the past decade, the incidence of anal sphincter ruptures has been increasing in Sweden and is currently estimated to occur in 2.5% of vaginal deliveries. The aim of the study was to report the frequency of a

I denna artikel diskuteras betydelsen av kroppen som en uppmärksam och aktiv aktör i rituell praktik, förankrad i en specifik social och historisk kontext, de kanadensiska mi’kmaqindianernas livsvärld. Mi’kmaqs möjlighet att arbeta om den kulturella kropp det dominerande samhället har implementerat i dem, öppnar nya vägar att göra sig av med destruktiva mönster som de medvetet eller omedvetet har

The aim of the present study was to find clinical parameters affecting incidence and progression of nephropathy in type 2 diabetic patients. A prospective study for 10 years was performed in 385 type 2 diabetic patients (diabetes diagnosis > or =30 years) attending a hospital-based outpatient clinic. Medical risk indicators like diabetes duration, HbA(1c), and blood pressure were related to the de